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Stallergenes S.A.: Positive Results From a Phase IIb/III Clinical Trial on the House Dust Mite Desensitization Tablet
Date:4/29/2009

's population may be affected by at least one allergy according to the ISAAC study. For nearly 15 to 20% of patients currently suffering from severe allergic rhinitis and rhinoconjunctivitis, their condition is not adequately controlled and has an adverse effect on their quality of life.

Sublingual desensitization therapy is fully recognized and coded by international consensus (ARIA), under the aegis of WHO. Supported by a high level of evidence, this consensus recommends the use of desensitization therapy when the patient's allergy is not adequately controlled by symptomatic treatments, which act on the symptoms of the condition without addressing its cause.

To date, desensitization therapy is the only treatment option that treats the immunological causes of allergies and modifies the natural course of the disease, preventing it from worsening.

Since 2003, Stallergenes has been running the Stalair(R) program, which aims to address the immunological cause of respiratory allergies with EBM-documented, registered allergen tablets. This program consists in the development of tablets for five of the main allergens triggering more than 80% of allergies: grass pollens, house dust mites, birch pollen, ragweed pollen, Japanese cedar pollen. The entire program is in the clinical development stage and is proceeding according to schedule.

The first tablet from the program, Oralair(R) (a desensitization tablet for grass pollens) is available in Germany for adults and children. This tablet is currently being evaluated in other European countries, with a view to bringing it to market in 2010.

About Stallergenes

Stallergenes is a European biopharmaceutical company dedicated to desensitization therapies for the prevention and treatment of allergy-related respiratory diseases, such as rhinoconjunctivitis, rhinitis and allergic asthma. A pioneer and leader in sublingual desensi
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