Navigation Links
St. Jude Study Finds Treatment With New Drug Might Make Tumor Cells More Sensitive to Therapy
Date:9/16/2008

ls lacking ATM, the team reported. The researchers also showed that CP466722 sensitized mouse cells to irradiation, an important finding since the team plans to study this effect in those models.

Finally, the team showed that exposure of HeLa cells to CP466722 for only four hours inhibits ATM sufficiently to enhance the cell's sensitivity to irradiation, and that after the compound's removal, the inhibition was rapidly and completely reversed. This suggested that a drug based on CP466722 might enable clinicians to treat patients with minimal doses for brief periods to achieve the maximum therapeutic effect.

Other authors of this report include Maura Charlton and Robert V. Stanton (Pfizer Research Technology Center, Pfizer Global Research and Development, Cambridge, Mass.).

This work was supported by Pfizer, the National Institutes of Health and ALSAC.

St. Jude Children's Research Hospital

St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tenn., St. Jude freely shares its discoveries with scientific and medical communities around the world. No family ever pays for treatments not covered by insurance, and families without insurance are never asked to pay. St. Jude is financially supported by ALSAC, its fundraising organization. For more information, please visit http://www.stjude.org.


'/>"/>
SOURCE St. Jude Children's Research Hospital
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. Eularis Releases First-Ever Study on ROI of Pre-Launch Named Patient Programmes
2. New Bisphenol A Study Has Limited Capability to Assess Human Health Effects
3. Symposium Highlights Yale Study Indicating Role of AHCC(R) for Immune System Enhancement and as a Promising Cancer Preventative
4. MannKind Reports Positive Data from a Phase 3 Clinical Study of Technosphere Insulin in Type 1 Diabetes
5. Latest RAD001 Study Results Show Further Increase in Time Without Tumor Growth in Patients With Advanced Kidney Cancer
6. AstraZeneca and Targacept Announce Top-Line Results from Phase IIb Study of AZD3480 in Alzheimers Disease
7. Most Cancer Treatment Studies Arent Published, Study Finds
8. Enanta Initiates Phase 1 Study on EDP-322, an Oral Antibiotic With Activity Against Hospital- and Community-Acquired MRSA
9. NicOx Announces Second Naproxcinod Pivotal Phase 3 Study (302) Meets Efficacy Primary Endpoints and Supports Non-Detrimental Blood Pressure Effect
10. Screening for Ischemia in Asymptomatic Patients With Type 2 Diabetes: Five- Year Outcomes in the DIAD Study
11. What is the Optimal Method of Ischemia Evaluation in WomeN: Preliminary Data from the WOMEN Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/17/2013)... , May 17, 2013 The power ... most important ways in which mankind depends on the ... Botanical Garden,s multifaceted exhibition Wild Medicine: ... Garden, on view from May 18 through September ... The featured exhibition,s many attractions include a ...
(Date:5/17/2013)...  Sorrento Therapeutics, Inc. (OTCBB: SRNE; or STI) ... Business Technology Transfer Research (STTR) grant (#1R42AI098182-02) from ... (NIAID), a division of the National Institutes of ... antibody therapeutics to combat Staphylococcus aureus ... methicillin-resistant S. aureus (MRSA), was renewed ...
(Date:5/17/2013)... 2013   Shareholder rights attorneys  at Robbins Arroyo ... (NASDAQGS: AVEO) securities has filed a complaint in the ... Massachusetts .  The complaint alleges that Aveo and ... of 1934 (the "Exchange Act") between January 3, 2012 ... (Logo: http://photos.prnewswire.com/prnh/20130103/MM36754LOGO ) Aveo ...
Breaking Medicine Technology:Wild Medicine On View at The New York Botanical Garden Through Sept. 8 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 2Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 3Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases 4Aveo Pharmaceuticals, Inc. Sued by Investor 2Aveo Pharmaceuticals, Inc. Sued by Investor 3
...  Millennium Laboratories announced today the Clinical Laboratory Responsibility ... responsible and ethical business practices in the medication ... which Millennium adheres and to which the company ... industry to adopt. (Logo: ...
... Inc., a critical care company focused on developing and commercializing ... Center for Devices and Radiological Health ... Administration (FDA) has granted 510(k) clearance for compatibility of its ... INOMAX DS and the INOMAX DSIR have now been validated ...
Cached Medicine Technology:Millennium Laboratories Announces Laboratory Responsibility Pledge 2Millennium Laboratories Announces Laboratory Responsibility Pledge 3FDA Clears Expanded Compatibility for INOMAX® Drug-Delivery Systems 2FDA Clears Expanded Compatibility for INOMAX® Drug-Delivery Systems 3
(Date:5/19/2013)... -- Although spring arrived late this year in parts ... still be strong, according to a sinus expert at ... Waguespack, clinical professor in the university,s division of otolaryngology, ... summer allergy season. However, some simple strategies can help ... he added. "Tree pollen has been bad for ...
(Date:5/19/2013)... Omaha, Nebraska is a city of diversity, economic ... of the lowest unemployment rates in the country. Forbes Magazine ... for Business and Careers and it consistently scores high on ... located in the nation and is a strong business leader ... of Editions TV are pleased to announce air ...
(Date:5/19/2013)... Park City, Utah (PRWEB) May 19, 2013 ... new information on small business health insurance ... alternatives to traditional employer sponsored health benefits, is ... contribution and health reimbursement arrangements . ... businesses, start-ups, and the self-employed intrinsically know the ...
(Date:5/19/2013)... 19, 2013 The report “Feed Additives ... & Forecasts up to 2017” published by MarketsandMarkets, defines ... analysis and forecasting of the global volume and revenue ... driving and restraining factors for the global market with ... challenges. The market is segmented and revenue is forecasted ...
(Date:5/19/2013)... (PRWEB) May 19, 2013 Dr. Keith Chertok ... help fight their unhealthy gums and increase the chance of ... Laser Assisted New Attachment Procedure (LANAP) not only removes diseased ... and strengthens the jaw bone for dental implants. ... diseased gum tissue. It can also help stimulate the healthy ...
Breaking Medicine News(10 mins):Health News:Managing Seasonal Allergies 2Health News:Editions TV Announces May Air Dates for Omaha, Nebraska 2Health News:Zane Benefits Publishes New Information on Small Business Health Insurance 2Health News:Zane Benefits Publishes New Information on Small Business Health Insurance 3Health News:Feed Additives Market to Reach $19.5 Billion by 2017 at a CAGR of 3.8% - New Report by MarketandMarkets 2Health News:Feed Additives Market to Reach $19.5 Billion by 2017 at a CAGR of 3.8% - New Report by MarketandMarkets 3Health News:Berkeley, CA Periodontist, Dr. Keith Chertok Now Treats Gum Disease Patients With Laser Gum Surgery Prior to Placing Dental Implants 2
... have not noticed a restriction in their access to ... Improvement and Modernization Act of 2003 (MMA), despite the ... to a new study led by researchers in the ... MMA often said that it would reduce patients access ...
... BEND, Ind., Oct. 7 OCS, Inc. and,Press ... into a,partnership, whereby the companies have combined their ... of products for the home,health care industry. The ... analysis of interrelated performance metrics integrating,patient satisfaction, patient ...
... They help ward off osteoarthritis, study suggests , TUESDAY, ... health may also help keep knee cartilage healthy and ... studies on the issue have produced conflicting findings, the ... knee osteoarthritis, while other studies found that exercise may ...
... Several medical groups,affiliated and aligned with Sutter ... the independent and highly respected health care leadership,group, ... part,of the IHA,s annual Pay for Performance (P4P) ... top performance are,Solano Regional Medical Group of the ...
... Following its recent,merger with Echo Therapeutics, Inc., ... platform-enabled transdermal specialty,therapeutics and diagnostics company, today announced ... Therapeutics, Inc., effective Monday, October 8,2007. In addition, ... Board,ticker symbol will change to "ECTE" and its ...
... and audio web cast on October 9, 2007 --, BELLEVILLE, ON, Oct. 5 /PRNewswire-FirstCall/ - ... Agriculture,(USDA) comment on a field trial for its E. coli O157:H7 cattle vaccine,during a: ... Conference Call & Audio Web Cast ... Tuesday, October 9, 2007 ...
Cached Medicine News:Health News:Medicare modernization act did not change chemotherapy as feared 2Health News:OCS and Press Ganey Partner to Create Joint Analysis of Outcomes and Satisfaction 2Health News:Heart-Healthy Workouts Help Knees, Too 2Health News:Sutter Health Medical Groups Among the Best for Health Care Quality 2Health News:Sontra Medical Corporation Changes Name to Echo Therapeutics, Inc. 2
... smoke evacuator is the ... smoke evacuation system when ... smoke evacuation attachment, Valleylab's ... either the Force FX™ ...
Simple, stable knee positioning triangles for lower extremity surgery. The triangles are radiolucent, autoclavable, and use latex-free, sterile, disposable pads....
Turnstile casting stand for easy and safe casting. The compact system sets up quickly and stores conveniently, and the non-stick coating prevents fiberglass or plaster from adhering to surface....
... optimal leg position for the seated patient and ... the foot/ankle at 90 degrees to the leg. ... the stand. Stockinette is pulled over the foot ... in a routine fashion. The cast stand is ...
Medicine Products: