St. Jude Identifies Genomic Causes of a Certain Type of Leukem... (lapse pathways will lead to understandin...)

St. Jude Identifies Genomic Causes of a Certain Type of Leukemia Relapse

Date:11/27/2008

lapse pathways will lead to understanding of the biological machinery of relapse, and ultimately to drugs that target that machinery. Such studies of the relapse machinery are now underway at St. Jude.

In other further studies, the researchers are also looking for other relapse-related genetic alterations besides copy number abnormalities. They are also applying their findings to adult ALL, in which relapse is a more significant problem than in the childhood disease.

Other authors of this paper include Letha Phillips, Xiaoping Su, Jing Ma, Christopher Miller and Sheila Shurtleff.

The research was supported in part by the National Health and Medical Research Council of Australia and ALSAC.

St. Jude Children's ResearchHospital

St. Jude Children's Research Hospital is internationally recognized for its pioneering work in finding cures and saving children with cancer and other catastrophic diseases. Founded by late entertainer Danny Thomas and based in Memphis, Tenn., St. Jude freely shares its discoveries with scientific and medical communities around the world. No family ever pays for treatments not covered by insurance, and families without insurance are never asked to pay. St. Jude is financially supported by ALSAC, its fundraising organization. For more information, please visit www.stjude.org.

SOURCE St. Jude Children's Research Hospital
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St. Jude Identifies Genomic Causes of a Certain Type of Leukem...(lapse pathways will lead to understandin...),Health