Navigation Links
Spherix Drug Candidate SPX-106 Shows Statistically Significant Reductions in Serum Triglycerides in Preclinical Testing
Date:6/2/2011

BETHESDA, Md., June 2, 2011 /PRNewswire/ -- Spherix Incorporated (NASDAQ: SPEXD) -- an innovator in biotechnology for therapy in diabetes, metabolic syndrome and atherosclerosis, and providers of technical and regulatory consulting services to food, supplement, biotechnology and pharmaceutical companies -- today announced that its drug candidate, SPX-106, achieved statistically significant reductions in triglycerides and cholesterol when administered in combination with D-tagatose for nine weeks to genetically engineered mice prone to dyslipidemia.

SPX-106 is one of five small molecules licensed by Spherix last year.  In early 2011, Spherix initiated the preclinical development of SPX-106 and D-tagatose as a treatment for hypertriglyceridemia.  In the recently completed study, treatment of animals using combination therapy with twice-daily oral dosing significantly reduced triglycerides by 43 mg/dl compared with control animals with a mean triglyceride level of 118 mg/dl (p=0.01).  The same therapy significantly reduced total cholesterol by 73 mg/dl from a mean level of 378 mg/dl compared with control animals (p=0.01).

SPX-106 is in preclinical development in combination with other agents, including D-tagatose, for the prevention and treatment of atherosclerosis, hypertriglyceridemia and related dyslipidemias.  The Company has initiated development of SPX-106 and D-tagatose as a treatment for hypertriglyceridemia, and plans to start an initial human efficacy study in the fourth quarter of 2011 or the first quarter of 2012.

"Spherix has toxicology, preclinical, clinical and other studies underway, and the findings of this preclinical study advance our understanding of the effects of SPX-106 and D-tagatose on triglycerides and cholesterol," said Dr. Claire Kruger, Chief Executive Officer of Spherix. "The market for triglyceride-lowering drugs exceeds $3 billion annually in the U.S. alone, and we believe that, should our stud
'/>"/>

SOURCE Spherix Incorporated
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Spherix Announces Registered Direct Offering of $2.77 Million
2. Spherix Announces Post-Hoc Analysis of Phase 3 Trial With D-Tagatose in Diabetes
3. Spherix Announces Third Quarter 2010 Financial Results
4. Spherix Awarded Grant from U.S. Government Under the Patient Protection and Affordable Care Act
5. Spherix Announces Institutional Investors Purchase $5.25 Million of Convertible Preferred Stock and Warrants
6. Spherix Completes Enrollment in NEET, a Phase 3 Clinical Trial Evaluating an Oral Drug for Type 2 Diabetes
7. Spherix to Present at Annual OneMedPlace Finance Forum and at EBD Biotech Showcase in San Francisco
8. Spherix Reports Third Quarter 2009 Earnings
9. Spherix Announces Positive Phase 2 Study Results
10. Spherix Reports First Quarter 2009 Earnings
11. Spherix Elects New Independent Director, and Elects Chairman of the Board
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... Jan. 23, 2015 Research and Markets ( ... "Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters ... Analysis, Size, Share, Growth, Trends and Forecast 2014 - ... At present, the global market for urinary catheters ...
(Date:1/23/2015)... 23, 2015  A new analysis of Centers for Medicare ... data shows that 81 percent of seniors chose lower-cost ... discounts at certain pharmacies. The findings were released by ... are now the foundation of Medicare Part D," said ...
(Date:1/23/2015)... 2015  MedScope ( www.medscope.org ), the leading provider of ... Connected World magazine Connected World Award for ... can be used anywhere, anytime. The nomination was made ... In nominating MedScope, Landon Garner , Director of ...
Breaking Medicine Technology:Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 2Urinary Catheters Market (Indwelling or Foley Catheters, Intermittent Catheters and Male External or Condom Catheters) - Global Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 - 2020 3New Analysis: 81 Percent of Medicare Part D Seniors Choose "Preferred Pharmacy" Plans in 2015 2MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2
... Inc. (NYSE: WPI ), a leading specialty ... and Chief Executive Officer, will provide an overview and ... Sachs 32nd Annual Global Healthcare Conference on Wednesday, June ... Resort in Rancho Palos Verdes, California. The presentation will ...
... BEDFORD, Mass., June 1, 2011 Hologic, Inc. ... ), a leading developer, manufacturer and supplier of premium ... serving the healthcare needs of women, today announced it ... of medical products in China, including Hologic,s ThinPrep Pap ...
Cached Medicine Technology:Hologic Acquires TCT International Co. Ltd., a Leading Distributor of Medical Products in China 2Hologic Acquires TCT International Co. Ltd., a Leading Distributor of Medical Products in China 3Hologic Acquires TCT International Co. Ltd., a Leading Distributor of Medical Products in China 4Hologic Acquires TCT International Co. Ltd., a Leading Distributor of Medical Products in China 5
(Date:1/22/2015)... January 22, 2015 The Incredible Bulk is ... Pakulski to increase lean muscle by up to 30lbs in ... the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative review. ... is a step-by-step, scientific diet formula that allows the body ...
(Date:1/22/2015)... York (PRWEB) January 22, 2015 The federal ... in the U.S. District Court, Southern District of West Virginia ... Inc. in that proceeding’s first bellwether trial. In an Order ... a new trial after finding that C.R. Bard had not ...
(Date:1/22/2015)... Autocarinsurancebest.com has released a new blog post explaining ... policy . , Auto insurance quotes help many drivers ... longer necessary to call an agent or visit an agency ... a single website: http://autocarinsurancebest.com/ . , Every business who ...
(Date:1/22/2015)... New York, NY (PRWEB) January 22, 2015 ... American College of Sports Medicine flagship journal Medicine ... supplementation with L-Citrulline before exercise may help reduce ... strenuous exercise. 1 , Participants in the ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Four years since the ... – which coincided with the marriage of Avasa & Matthew Love ... ROAD, which is scheduled for release through White Swan Records on ... that there is a sacred path available to all of us ...
Breaking Medicine News(10 mins):Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... Personal Protective Equipment Conference 2009 (PPE 2009), which ... in Fort Lauderdale, FL, November 17 - 19, 2009, ... networking resource for firefighters, law enforcement officers, military personnel, ... technicians, veterinary specialists, rescue team members, and other first ...
... , MetLife Foundation and Partnership for a ... Resources to Help Parents Talk to their Teens , ... MetLife Foundation will begin the next phase of its award-winning parenting ... for a Drug-Free America(R) on radio stations in 14 markets nationwide ...
... , LONDON, Sept. 14 The 2009 Frost ... is presented to Kemin Health. , , ... Health,s Slendesta is the only appetite suppressant in the weight ... dietary staple. The protein-based Slendesta is distinct from fibre-based equivalents; ...
... , , Collaboration will ... care , , BOSTON, Sept. 14 ... enable patients who are seen at Children,s ambulatory programs and in ... to aggregate health data from both sites of care into a ...
... , MARKHAM, ON, Sept. 14 /PRNewswire-FirstCall/ - AlphaRx Inc. ... Renshaw Healthcare Conference in New York City, ... focusing on the Company,s product pipeline, nano drug delivery ... 12 months. In Summary, AlphaRx will have 3-4 products ...
... /PRNewswire-FirstCall/ - SXC Health Solutions Corp. ("SXC" or the ... announced it has entered into a strategic relationship with ... electronic prescribing (e-prescribing) options available to SXC,s healthcare benefits ... - health plans, employers, government agencies, pharmacy benefit managers ...
Cached Medicine News:Health News:Personal Protective Equipment Conference Set for November 17 - 19 in Fort Lauderdale 2Health News:Award-Winning Drug Awareness Campaign Enters Next Phase 2Health News:Award-Winning Drug Awareness Campaign Enters Next Phase 3Health News:Award-Winning Drug Awareness Campaign Enters Next Phase 4Health News:Frost & Sullivan Honours Kemin Health With Global Weight Management Ingredients New Product Innovation Award 2Health News:Frost & Sullivan Honours Kemin Health With Global Weight Management Ingredients New Product Innovation Award 3Health News:Frost & Sullivan Honours Kemin Health With Global Weight Management Ingredients New Product Innovation Award 4Health News:Children's Hospital Boston, eClinicalWorks Team to Push Clinical Information Into Patients' Personally Controlled Health Records 2Health News:Children's Hospital Boston, eClinicalWorks Team to Push Clinical Information Into Patients' Personally Controlled Health Records 3Health News:Children's Hospital Boston, eClinicalWorks Team to Push Clinical Information Into Patients' Personally Controlled Health Records 4Health News:Children's Hospital Boston, eClinicalWorks Team to Push Clinical Information Into Patients' Personally Controlled Health Records 5Health News:AlphaRx Presents Company Overview and New Product Candidates at the Rodman Renshaw Healthcare Conference 2Health News:SXC Health Solutions teams with Allscripts to deliver critical prescription information to physicians at the point-of-care 2Health News:SXC Health Solutions teams with Allscripts to deliver critical prescription information to physicians at the point-of-care 3Health News:SXC Health Solutions teams with Allscripts to deliver critical prescription information to physicians at the point-of-care 4Health News:SXC Health Solutions teams with Allscripts to deliver critical prescription information to physicians at the point-of-care 5
Measles IgM ELISA test is an enzyme linked immunosorbent assay (ELISA) for the detection of IgG class antibodies to Measles (Rubeola) in human serum or plasma....
Measles IgM ELISA test is an enzyme linked immunosorbent assay (ELISA) for the detection of IgG class antibodies to Measles (Rubeola) in human serum or plasma....
... over 30 years, Digisonics has set ... with the first review station, the ... and the best multi-modality reporting., ,DigiView ... image review workstations, professional reporting choices, ...
... osmolality at room temperature with the sample ... are cryoscopic artifacts due to high viscosity, ... with freezing point determinations. The superbly accurate ... osmometer has a much broader range of ...
Medicine Products: