Perfexion is an ideal system to treat metastases – particularly for patients with multiple lesions, as the system's advanced collimator facilitates rapid isocenter changes. At Hospital Ruber Internacional, 80 percent of mets patients have more than one lesion, Dr. Martinez notes.
"The mean number of mets nowadays is four mets per patient," he says. "Referred patients will come to us with a diagnosis of one to two mets. However, we will perform an MRI with a double dose of contrast for mets patients, and we have found that in 70 percent of these cases, the number of mets is actually larger."
Patients with metastases represent about 20 percent of Ruber's Gamma Knife radiosurgery volume. Meningiomas and other benign tumors make up 40 percent, while 25 percent of radiosurgery cases are for vascular malformations. Although functional disorders, such as trigeminal neuralgia amount to just eight percent of Ruber's Gamma Knife cases now, they are a growing indication.
"Since 1998, we have treated 500 functional cases, mostly trigeminal neuralgia, but the trend is for more of these cases. We hope that in the near future that up to 12 percent of our indications are for functional disorders," Dr. Martinez says.
Installed in 48 countries, more than 300 Gamma Knife systems are currently in clinical use, with more than 700,000 patients treated worldwide.
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