Navigation Links
Sosei and Vectura Announce Start of Phase III Clinical Study With NVA237
Date:6/28/2009

CHIPPENHAM, England and TOKYO, June 29 /PRNewswire/ --

- Study Triggers $7.5m Milestones for Both Companies

Sosei Group Corporation ("Sosei"; TSE Mothers Index: 4565) and Vectura Group plc ("Vectura"; LSE: VEC) announce the commencement of a Phase III clinical study by Novartis, with NVA237, a once-daily, long-acting muscarinic antagonist (LAMA) for the treatment of chronic obstructive pulmonary disease (COPD). NVA237 is a dry powder formulation for oral inhalation of glycopyrronium bromide, a LAMA with a rapid onset of activity. The study has now appeared on clinicaltrials.gov and will be recruiting in the next few weeks when the first patient first visit will trigger a $7.5 million milestone payment to both Sosei and Vectura.

The trial is a randomised, double-blind, placebo-controlled, parallel-group design, including an open-label tiotropium bromide arm, and will assess efficacy, safety and tolerability of NVA237 in patients with COPD. It will include approximately 1000 patients with moderate to severe COPD from study centres across the USA, Europe and other territories. Each patient will be randomised to receive a once-daily dose of placebo, tiotropium bromide or 50microg of NVA237 for a 52-week period. The primary endpoint of the study will be the change from baseline in FEV1 (forced expiratory volume in one second) over 12 weeks of treatment. A number of secondary endpoints will also be evaluated.

NVA237 was licensed to Novartis in April 2005 by Sosei and its co-development partner Vectura. Novartis intends to launch NVA237 as a once-daily monotherapy for COPD and also in combination with Novartis' investigational once-daily, long-acting beta2-agonist (LABA) indacaterol (QAB149), which was filed for approval with the regulatory authorities as a monotherapy treatment for COPD at the end of 2008. The combination of NVA237 and indacaterol is known as QVA149. NDA submissions
'/>"/>

SOURCE Sosei Group
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Sosei Announces Completion of Phase III Trial for NorLevo(R)
2. Sosei and NeuroSolutions Present Further Data on NSL-043/SD118 at the Society for Neuroscience 38th Annual Meeting
3. Sosei Confirms the Safety of SD118 in Two Phase I Trials
4. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
5. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
6. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
7. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
8. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
9. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
10. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
11. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/25/2014)... According to a new market ... Insulin Market (Rapid-Acting, Short-Acting, Intermediate-Acting, Long-Acting, Premixed, Modern and ... and Forecast (Value and Volume), 2013 - 2019", the ... in 2012 and is expected to grow at a ... USD 32.24 billion in 2019. Browse the ...
(Date:7/25/2014)... DUBLIN , July 25, 2014 ... the "Global Ophthalmic Diagnostic Devices Market 2014-2018" ... http://photos.prnewswire.com/prnh/20130307/600769 About Ophthalmic Diagnostic Device ... device used to identify a defect or deficiency in ... patients with ophthalmic disorders such as presbyopia, cataracts, glaucoma, ...
(Date:7/25/2014)... Pa. , July 25, 2014  AMETEK, Inc. ... of Kurtis L. Goos as Vice President ... Materials, Interconnects and Packaging (EMIP) Division. "I ... extensive general management and business development experience, especially in ... make important contributions to the continued growth and success ...
Breaking Medicine Technology:Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 2Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 3Global Insulin Market Expected to Reach USD 32.24 Billion Globally in 2019: Transparency Market Research 4Global Ophthalmic Diagnostic Devices Market 2014-2018: Key Vendors are Alcon, Carl Zeiss, Haag-Streit and Topcon 2AMETEK Names Kurtis L. Goos, Vice President & General Manager, Engineered Medical Components 2
... Study Success in Using Virus Enzyme to Treat Mouse ... Be Used to,Prevent Both Ear Infection and Pneumonia in ... -- Parents might one,day give their children a weekly ... them from getting a severe middle ear,infection, based on ...
... the Drug Improves Memory, SARASOTA, Fla., March 22, ... it has received positive,preliminary results in its major ... application for the treatment of Alzheimer's,disease. The clinical ... first human clinical study conducted by a,Florida-based research ...
Cached Medicine Technology:Viral Enzyme Recruited in Fight Against Ear Infection 2Viral Enzyme Recruited in Fight Against Ear Infection 3Sarasota's Roskamp Institute Announces Positive Safety Data in,Human Clinical Study for Alzheimer's Disease 2
(Date:7/27/2014)... The North American security and surveillance ... million in 2014, and it is expected to reach ... The report incorporates the factors that influence a country’s ... rates and projected total expenditure. The report also throws ... Apart from the general overview of the companies, it ...
(Date:7/27/2014)... (PRWEB) July 27, 2014 The report, ... (Passenger Cars, LCVs & HCVs), Market Type (OE & ... & Diesel) & Geography - Industry Trends & Forecast ... and fuel filters market with analysis and forecasting of ... oil filters is estimated to reach a revenue of ...
(Date:7/27/2014)... 27, 2014 The European Agricultural Adjuvants ... Europe with analysis and forecast of revenue. The agricultural ... around $509.4 million in 2013 to $657.1 million by ... 2018. , Browse through the TOC of the European ... the in-depth analysis provided. It also provides a glimpse ...
(Date:7/27/2014)... 27, 2014 The report provides ... Aviation - Market Analysis (Commercial Aviation And Defense ... Hydraulic, Mechanical) - Forecasts 2014 - 2019." The ... expected to shape the market during the study ... technology trends that are currently prevailing in the ...
(Date:7/27/2014)... 2014 Metachromatic leukodystrophy (MLD, also ... disease which is commonly listed in the family ... as it affects the metabolism of sphingolipids. Leukodystrophies ... fatty covering which acts as an insulator around ... systems. MLD involves cerebroside sulfate accumulation. Metachromatic leukodystrophy, ...
Breaking Medicine News(10 mins):Health News:North America Security and Surveillance Radar Market is Expected to Reach $2030 million in 2019 - New Report by MicroMarket Monitor 2Health News:North America Security and Surveillance Radar Market is Expected to Reach $2030 million in 2019 - New Report by MicroMarket Monitor 3Health News:North America Security and Surveillance Radar Market is Expected to Reach $2030 million in 2019 - New Report by MicroMarket Monitor 4Health News:North America Security and Surveillance Radar Market is Expected to Reach $2030 million in 2019 - New Report by MicroMarket Monitor 5Health News:Oil Filter & Fuel Filter Market Worth $18.6 Billion by 2018 - Report by MarketsandMarkets 2Health News:Oil Filter & Fuel Filter Market Worth $18.6 Billion by 2018 - Report by MarketsandMarkets 3Health News:Oil Filter & Fuel Filter Market Worth $18.6 Billion by 2018 - Report by MarketsandMarkets 4Health News:Oil Filter & Fuel Filter Market Worth $18.6 Billion by 2018 - Report by MarketsandMarkets 5Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 2Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 3Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 4Health News:Europe Agricultural Adjuvants Market is Expected to Reach $657.1 million in 2018 - New Report by MicroMarket Monitor 5Health News:Actuator Systems Market in Aviation Estimated to Reach $3,839.74 Million by 2019 - New Report by MarketsandMarkets 2Health News:Actuator Systems Market in Aviation Estimated to Reach $3,839.74 Million by 2019 - New Report by MarketsandMarkets 3Health News:Actuator Systems Market in Aviation Estimated to Reach $3,839.74 Million by 2019 - New Report by MarketsandMarkets 4Health News:Metachromatic Leukodystrophy Therapeutics Clinical Trials Market Review H2 2014 Report Available at LifeScienceIndustryResearch.com 2Health News:Metachromatic Leukodystrophy Therapeutics Clinical Trials Market Review H2 2014 Report Available at LifeScienceIndustryResearch.com 3Health News:Metachromatic Leukodystrophy Therapeutics Clinical Trials Market Review H2 2014 Report Available at LifeScienceIndustryResearch.com 4Health News:Metachromatic Leukodystrophy Therapeutics Clinical Trials Market Review H2 2014 Report Available at LifeScienceIndustryResearch.com 5
... developed a thirst sensor designed to alert the elderly when ... ,The device evaluates the relationship between bodily fat, water ... too little water. ,Four tiny contact strips are ... to a pocketbook-sized apparatus carried next to the body. ...
... might have finally cracked the mystery of the deaths ... Top End.// ,Eye and throat disease had killed ... End's five crocodile farms in recent past weeks. ... suggests the unusually cold dry season and exposure of ...
... are not getting enough sun, and as a result, ... a comeback, experts have revealed in the latest Medical ... rickets are again emerging as major paediatric health issues ... paediatric endocrinologist at the Children’s Hospital at Westmead, Sydney. ...
... ,Egypt is bracing itself for an outbreak of the deadly ... and Sohaj governorates.// ,The first of these cases was ... some 490 kilometers or 305 miles south of Cairo. ... slaughtered and tests are underway to check that none of ...
... women of childbearing age, who would indeed be wise to ... a child with birth defects. // , ,The ... of vitamins and minerals, the risk of many severe birth ... include neural-tube defects such as spina bifida, brain-damaging hydrocephalus, heart ...
... skilled prescribing, warn doctors in this week’s BMJ.Evidence of ... Aronson and colleagues.// Effective treatments are often underprescribed and ... work in hospitals. ,The reasons for ... to system failures, while another fundamental problem is that ...
Cached Medicine News:Health News:More Sunshine for At-Risk Kids 2Health News:Many Medical Students Unprepared for Skilled Prescribing 2
Capable of producing up to 500 volts and 500 milliamps, this power supply is ideal for PAGE, SDS-PAGE, DNA or RNA submarine gels as well as all types of small format transfer apparatus....
... IEF to DNA sequencing, Thermo Series 90 ... routine electrophoretic applications. These power supplies ... or constant power operating modes, with automatic ... power of the Series 90 power supplies, ...
... for horizontal and vertical gel electrophoresis applications. ... In this power supply model, output is ... constant voltage. Four sets of output terminals ... This power supply's light, compact and stackable ...
The Programmable MP-3500P-F Power Supply can be applied for any Microfluidic application....
Medicine Products: