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Sosei and NeuroSolutions Present Further Data on NSL-043/SD118 at the Society for Neuroscience 38th Annual Meeting
Date:11/18/2008

LONDON, November 19 /PRNewswire-FirstCall/ -- NeuroDiscovery Ltd (ASX: NDL), a specialty neuroscience service provider and drug development Company, and Sosei Group Corporation ("Sosei"; TSE Mothers Index: 4565), a leading international biopharmaceutical company, today announce that NeuroSolutions is presenting further pivotal pre-clinical efficacy data for NSL-043/SD118. This investigational drug is a potential therapy for neuropathic pain and has successfully completed Phase I clinical studies and is now ready for Phase II studies.

The data presented demonstrate that NSL-043/SD-118 reverses static allodynia and inhibits spontaneous ectopic discharge in the streptozotocin-induced diabetic neuropathy and chronic constriction injury models of neuropathic hypersensitivity and suggest that this compound may be effective in treating neuropathic pain in man.

NSL-043/SD118 is being jointly developed by NeuroDiscovery and its wholly owned subsidiary NeuroSolutions Ltd under a collaboration agreement with Sosei concluded in June 2006. NSL-043/SD118 was previously under clinical investigation in Japan for a different indication and demonstrated a potential new use as an oral therapy in neuropathic pain through a re-profiling collaboration.

Dr Chris Moyses, Group Chief Executive of NeuroDiscovery, commented: "We are delighted to announce these important observations which represent a valuable endorsement of the Company's approach to discovering first-in-class compounds that are clearly differentiated from existing therapeutics used in the management of neuropathic and inflammatory pain."

Mr Shinichi Tamura, CEO Sosei Group added: "We are pleased to have collaborated with NeuroDiscovery on this project and to have generated a clinical asset in an area of significant unmet medical need."

Neuroscience 2008, the Society for Neuroscience's 38th annual meeting, is scheduled for Nov. 15 t
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SOURCE Sosei Group Corporation
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