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Sorrento Therapeutics Awarded NIH Grant for MRSA Program
Date:5/21/2010

ey also cited the high quality of the investigational team and the impressive preliminary data supporting the program to date. In January, the Company obtained an exclusive license to The Scripps Research Institute's quorum quenching technology, which lays the scientific foundation for this program.

"We believe that the use of quorum sensing signal molecules as targets for the development of vaccines and antibody therapeutics using our proprietary technology platform is a novel and promising approach to combat a serious public health issue. We look forward to working with our colleagues at The Scripps Research Institute and Montana State University in developing novel antibody therapeutics and vaccines against MRSA," said Charlie Rodi, Ph.D., Vice President of Research and Development at Sorrento Therapeutics and the Principal Investigator on the grant.

For 2005, the Centers for Disease Control and Prevention estimated that 94,000 serious invasive MRSA infections occurred in the U.S. and more than 19,000 Americans died from these infections - more than from HIV/AIDS. A recent (2009) study from Duke University Medical Center looking at MRSA infections associated with surgery found a 35-fold increased risk of hospital readmission, a 7-fold increased risk of death, and more than $60,000 of additional charges per patient compared to uninfected controls. IMS Health reported that U.S. sales of antibiotics to treat MRSA exceeded $1 billion in 2007. Although a report from the Government Accounting Office indicates that no federal agency adequately monitors antibiotic resistance or evaluates its social and financial costs, various estimates place the annual cost to the healthcare system as high as

SOURCE Sorrento Therapeutics, Inc.
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