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Sorrento Therapeutics, Inc. announces its approach to developing human antibody therapeutics against MRSA receives continued support from the National Institute of Allergy and Infectious Diseases
Date:5/17/2013

n , Ph.D., the Principal Investigator on the grant and a director of research at STI. More comprehensive data analyses will be presented in future conferences or scientific publications.

"We believe that targeting quorum sensing signal molecules using our proprietary technology is an innovative and promising strategy for the prevention and possibly treatment of serious S. aureus infections, including those caused by antibiotic-resistant MRSA strains, as we expect that our antibodies may not be affected by existing drug resistances. We look forward to continue working with our colleagues at Montana State University in developing the novel human antibody therapeutics against MRSA" said Dr. Gunnar F. Kaufmann , the Senior Director of Research and Development at STI and co-inventor of the quorum quenching technology.

For 2005, the Centers for Disease Control and Prevention (CDC) estimated that 94,000 serious invasive MRSA infections occurred in the U.S. and more than 19,000 Americans died from these infections - more than from HIV/AIDS. A 2009 study from Duke University Medical Center looking at MRSA infections associated with surgery found a 35-fold increased risk of hospital readmission, a 7-fold increased risk of death, and more than $60,000 of additional charges per infected patient compared to uninfected patients. While the number of life-threatening invasive MRSA infections has begun to decline according to the CDC, a recent report from the Alliance of Prudent Use of Antibiotics (APUA; www.apua.org) indicated that antibiotic-resistant infections overall cost the US healthcare system more than $20 billion each year.

About Sorrento Therapeutics, Inc.

Sorrento Therapeutics, Inc. is a publicly-traded, development-stage biopharmaceutical company focused on the discovery, development and commercialization of novel and proprietary biotherapeutics for the treatment
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