Navigation Links
Sorbent Therapeutics' CLP1001 Improves Heart Failure Symptoms In Phase 2 Clinical Study
Date:5/22/2012

Officer.  "CLP1001 could ultimately be used alongside standard medications to improve the physical functionality and overall quality of life of these heart failure patients."

About the Phase 2a Study
The double-blind, randomized, parallel, placebo-controlled study examined the effect of CLP1001 over eight weeks in 111 heart failure patients with chronic kidney disease (CKD). 

CLP1001-treated patients achieved significantly greater weight loss – an accepted measurement of fluid retention – as compared to placebo over the first two weeks of treatment.  This trend continued through the end of the study.  After eight weeks of treatment, a greater number of patients experienced marked or moderately improved breathing in the CLP1001 group and the average distance walked in the 6-Minute Walk Test was larger in patients receiving CLP1001 versus the placebo population.  CLP1001 improved functional heart capacity as assessed by the New York Heart Association (NYHA) classification by at least one class compared to the placebo group (48.8% vs. 17.4%; p=0.002).  Similar results favoring the CLP1001 group were seen when examining quality of life.

These data were presented by Dr. Costanzo during the Late-Breaking Trials 2 Special Session at the ESC Heart Failure Congress in a talk titled "A Double-Blind, Randomized, Parallel, Placebo Controlled Study Examining the Effect of Cross-linked Polyelectrolyte (CLP) in Heart Failure Patients with Chronic Kidney Disease – Sorbent  CTST-21." 

About Heart Failure
Heart failure is a progressive condition in which the heart muscle becomes weakened after it is injured, most commonly from heart attack or high blood pressure, and gradually loses its ability to pump enough blood to supply the body's needs.  Many people are not aware they have heart failure because the symptoms are often mistaken for signs of getting older.  Hea
'/>"/>

SOURCE Sorbent Therapeutics
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Allied Healthcare Announces Litholyme(TM) -- New CO2 Absorbent Used in Anesthesia
2. Reportlinker Adds US Enzyme-Linked Immunosorbent Assay (ELISA) Industry
3. Sorbent Therapeutics Completes $36 Million Series B Financing for Net of $53 Million
4. CytoSorbents Corporation to Exhibit at the Advanced Technology Applications for Combat Casualty Care Conference
5. Vicus Therapeutics to Present at the 234th American Chemical Society National Meeting in Boston, MA
6. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
7. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
8. TorreyPines Therapeutics Completes Patient Enrollment in Phase IIb Clinical Trial of Tezampanel for the Treatment of Acute Migraine Headache
9. CV Therapeutics Announces Eight Abstracts Accepted for Presentation at the European Society of Cardiology Congress 2007
10. Pharmacopeia Assists the World Health Organization in the Discovery of Novel Therapeutics for the Treatment of Malaria
11. Protalix BioTherapeutics Treats First Patient in Phase III Clinical Trial of prGCD
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... LONDON , December 24, 2014 /PRNewswire/ ... expected to grow at an average rate of 8.1%. ... and volume. Hip, knee and spine surgeries are the ... emerging economies they have a lower penetration. Increased number ... use of composites. Non-metallic orthopedic devices have gained popularity ...
(Date:12/24/2014)... Dec. 23, 2014  Advanced Medical Isotope Corporation ... primarily in the development of brachytherapy devices and ... announced that it has filed a de ... Administration ("FDA") for marketing clearance for its patented ... the U.S. Food, Drug and Cosmetic Act (the ...
(Date:12/24/2014)... , Dec. 23, 2014   Synageva BioPharma ... biopharmaceutical company developing therapeutic products for rare disorders, ... (EMA) of the Marketing Authorization Application (MAA) for ... granted the company,s request for accelerated assessment, which ... review time.   The MAA, and ...
Breaking Medicine Technology:Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 2Use of Composites in Orthopedic Industry to Reach $596 Million by 2020 3Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 2Advanced Medical Isotope Corporation Files a "de novo" Submission for Y-90 RadioGel(TM) Device 3Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3
... Pharmaceutical Care Management Association (PCMA) President and CEO ... Pentagon,s new budget proposal which includes a provision encouraging ... to save money: "The Pentagon,s budget proposal ... of generics and mail-service pharmacies reduces costs and enhances ...
... 15, 2011 Boston Scientific Corporation (NYSE: ... technologies to treat peripheral chronic total occlusions (CTOs).  These ... portfolio of devices for lower extremity peripheral artery disease. ... in November 2010 from S.I. Therapies, Ltd., based in ...
Cached Medicine Technology:Boston Scientific Acquires Two Novel Technologies to Treat Peripheral Chronic Total Occlusions 2Boston Scientific Acquires Two Novel Technologies to Treat Peripheral Chronic Total Occlusions 3Boston Scientific Acquires Two Novel Technologies to Treat Peripheral Chronic Total Occlusions 4
(Date:12/25/2014)... The report “Nintedanib (Colorectal Cancer) – ... the current treatment landscape, unmet needs, current pipeline ... Stivarga is a drug which is used in ... Ingelheim is developing nintedanib (BIBF-1120), an orally available ... in the US, Europe, and Japan. The drug ...
(Date:12/25/2014)... Dylan Queen, a famous online company supplying women’s special ... prom dresses, most of which are priced under $200. ... the promotion is valid until Jan. 22, 2015; the ... market. , The prom dresses in this new collection ... strapless, empire strapless chiffon, one shoulder, floor-length, V-neck beading, ...
(Date:12/25/2014)... FL (PRWEB) December 25, 2014 When head ... find themselves in a frenzy to get rid of it ... But families in Coral Gables now have the solution right ... second salon clinic location, Lice Troopers provides full spectrum head ... the Coral Gable area, including Sunset, Key Biscayne, Brickell, Coconut ...
(Date:12/25/2014)... -- Among early stage breast cancer patients who undergo ... percent will eventually develop leukemia as a result of ... comes from a review of more than 20,000 breast ... suggests that the risk for developing treatment-related leukemia, though ... "The frequency of bone marrow cancers such as ...
(Date:12/25/2014)... 25, 2014 Plugin creators from Pixel ... A fully customizable business presentation tool made specifically for ... ProFire 5k business tool, users can now display their ... of Pixel Film Studios. “ProFire 5k gives users a ... add professionalism to a presentation” , Pixel Film Studios ...
Breaking Medicine News(10 mins):Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 2Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 3Health News:Nintedanib Colorectal Cancer Market Analysis and Forecast to 2023 Report at RnRMarketReserach.com 4Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Coral Gables Florida Gets Ready to Be Lice-Free with Lice Troopers 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 2Health News:Breast Cancer Chemo Tied to Small But Significant Leukemia Risk 3Health News:Announcing a new ProFire 5k plugin from Pixel Film Studios for Final Cut Pro X Professionals 2
... of biology in the School of Science at Indiana ... eye and vision research organization in the world for ... blindness caused by macular degeneration, retinitis pigmentosa and other ... Research in Vision and Ophthalmology (ARVO) will present Meyer ...
... researchers have shown for the first time how peppermint ... to 20% of the population. In a paper ... , researchers from the University,s Nerve-Gut Research Laboratory explain ... soothing inflammatory pain in the gastrointestinal tract. Dr ...
... shows how inflammation can help cause cancer. Chronic inflammation ... inflammatory bowel disease is associated with up to 25 ... the Ohio State University Comprehensive Cancer Center Arthur ... Institute (OSUCCC James) found that inflammation stimulates a ...
... more effective than cutting calories for individuals who want to ... UT Southwestern Medical Center researchers. "What this study tells ... to reduce the amount of fat in your liver, you ... assistant professor of internal medicine at UT Southwestern and the ...
... , MONDAY, April 18 (HealthDay News) -- Patients with do-not-resuscitate ... after surgery, even after non-emergency procedures, a new study finds. ... used to revive someone who is clinically unresponsive and lacks ... and in the August print issue of the journal ...
... , MONDAY, April 18 (HealthDay News) -- Infection ... of many college students -- and little exposure to sunlight ... sclerosis, a new study suggests. "MS is more common ... lead researcher, Dr. George C. Ebers, of the University of ...
Cached Medicine News:Health News:IUPUI faculty member to receive national innovative vision research award 2Health News:Peppermint earns respect in mainstream medicine 2Health News:Study shows how inflammation can lead to cancer 2Health News:Limiting carbs, not calories, reduces liver fat faster, UT Southwestern researchers find 2Health News:People With DNR Orders More Apt to Die After Any Surgery 2Health News:Can Common Virus, Lack of Sunlight Boost MS Risk? 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: