Navigation Links
Soligenix Submits NIAID Contract Proposal for Development of a Thermostable Ricin Vaccine
Date:10/31/2013

formulations using adjuvants, protein immunogens, and other components that ordinarily would not withstand long temperature variations exceeding customary refrigerated storage conditions. These studies were conducted with our aluminum-adjuvanted ricin toxin vaccine, RiVax™, made under precise lyophilization conditions using excipients that aid in maintaining native protein structure of the ricin A chain, the immunogenic compound of the vaccine. When RiVax™ was kept at 40 degrees Celsius for six months, all of the animals vaccinated with the lyophilized RiVax™ vaccine developed potent and high titer neutralizing antibodies. Confirmatory results have extended the stability to six months when the vaccine is kept at 40 degrees Celsius. In contrast, animals that were vaccinated with the liquid RiVax™ vaccine kept at 40 degrees Celsius did not develop neutralizing antibodies and were not protected against ricin exposure. The ricin A chain is extremely sensitive to temperature and rapidly loses the ability to induce neutralizing antibodies when exposed to temperatures higher than 8 degrees Celsius.

The underlying lyophilization technology was discovered by Drs. John Carpenter and Theodore Randolph at the University of Colorado, the inventors of the technology underlying the ThermoVaxTM products. 

About Ricin Toxin

The Centers for Disease Control has classified ricin toxin as a Category B biological agent. Currently, there are no FDA approved therapeutics or vaccines that can be used to protect against ricin exposure or to reverse its effects once exposed. Ricin toxin is a protein that consists of an A and B subunit that can be extracted from the beans of the castor plant, Ricinus communis. The potential use of ricin toxin as a biological weapon of mass destruction has been highlighted in an FBI Bioterror report released in November 2007, entitled
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
2. Soligenix Reports First Quarter 2012 Financial Results and Highlights Recent Accomplishments
3. Soligenix Reports Second Quarter 2012 Financial Results and Highlights Recent Accomplishments
4. Soligenix Announces Issuance of US Patent for Topically Active Steroids to Treat Inflammatory Gastrointestinal Disorders
5. FDA Grants Soligenix Fast Track Designation for SGX203 for the Treatment of Pediatric Crohns Disease
6. Soligenix Reports Third Quarter 2012 Financial Results and Highlights Recent Accomplishments
7. FDA Grants Soligenix Fast Track Designation for OrbeShield(TM) for the Reduction of Mortality Associated with Gastrointestinal Acute Radiation Syndrome (GI ARS)
8. Soligenix Announces Formation of Oral Mucositis Medical Advisory Board
9. Soligenix to Present at 15th Annual BIO CEO & Investor Conference
10. Soligenix Receives IND Clearance from FDA to Initiate Clinical Program to Evaluate SGX942 for the Treatment of Oral Mucositis
11. Soligenix to Present at World Vaccine Congress & Expo
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/2/2015)... Mass. , July 2, 2015   ... and European retinal specialists identify less frequent dosing ... edema (DME), due to the burden on both ... anti-vascular endothelial growth factor (VEGF) injections, which are ... Allergan/Molecular Partners, abicipar pegol, which is in development ...
(Date:7/2/2015)... , July 2, 2015 ... (Homofermentative & Heterofermentative), Species (Lactobacillus, Pediococcus & Enterococcus), Enzymes ... and Forecast to 2020", Silage Inoculants & Enzymes Market ... a CAGR of 4.0% from 2015 to 2020. ... igures spread through 194 P ...
(Date:7/2/2015)...  Konica Minolta, Inc. (Konica Minolta) ( Tokyo ... Sawae Technologica Ltda., an X-ray system equipment manufacturer based ... its Brazilian healthcare sales company, Konica Minolta Healthcare do ... Brazil market investment and growth With ... million, significant healthcare technical advancements and efficiencies are required. ...
Breaking Medicine Technology:Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 2Retinal Specialists Indicate Strong Desire for DME Therapies Which Induce Greater Vision Gains or are Administered Less Frequently Than Currently Approved Anti-VEGF Therapies 3Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 2Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 3Silage Inoculants & Enzymes Market Worth $489.05 Million by 2020 4Konica Minolta Acquires Sawae, Enhancing Digital X-ray Diagnostic Imaging Systems in Brazil 2Konica Minolta Acquires Sawae, Enhancing Digital X-ray Diagnostic Imaging Systems in Brazil 3
... 2011 Assured Pharmacy, Inc. (Other OTC: APHY.PK), a ... than 3,000 sufferers of chronic pain, announced that it ... its fifth pharmacy location.  Subject to regulatory approval, the ... Fourth Quarter of 2011.  It will join the Company,s ...
... 27, 2011 Reportlinker.com announces that a ... its catalogue: India Cardiac ... 2016 http://www.reportlinker.com/p0575381/India-Cardiac-Catheters-and-Guidewires---Market-Trends-Till-2016.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Surgical_Equipment ... This market report provides vital market ...
Cached Medicine Technology:Assured Pharmacy Signs Lease in Kansas City, Kansas for its Fifth Pharmacy Location 2Assured Pharmacy Signs Lease in Kansas City, Kansas for its Fifth Pharmacy Location 3India Cardiac Catheters and Guidewires - Market Trends Till 2016 2India Cardiac Catheters and Guidewires - Market Trends Till 2016 3
(Date:7/4/2015)... ... ... Dating a real millionaire online can be more difficult. Millionairematchapp.com is ... remove the worries from meeting partners. Recently, the site announced they're publishing of ... readers have responded with excitement. , “There's quite a few millionaire dating apps ...
(Date:7/4/2015)... New York, NY (PRWEB) , ... July 04, 2015 , ... ... suggest that 15% of chronic pain sufferers have pain located in the neck. Another ... referred from the neck. Chiropractic literature suggests that 45% of American workers ...
(Date:7/4/2015)... ... 04, 2015 , ... Tyler Boden, Project Developer of Sullivan ... from the North American Board of Certified Energy Practitioners (NABCEP®), and is now ... and well established national certification organization for renewable energy professionals. Designation as a ...
(Date:7/3/2015)... ... July 03, 2015 , ... Brendon Burchard's new High ... of media attention. In an effort to spread the news, a comprehensive review ... days many people are feeling overwhelmed by stress and fatigue," reports Hendricks. "Many ...
(Date:7/3/2015)... SC (PRWEB) , ... July ... ... has announced the sessions and speaker lineup for its 2015 Annual ... taking place August 6-8, 2015 at the Renaissance Orlando at SeaWorld in ...
Breaking Medicine News(10 mins):Health News:MillionaireMatchapp.com Publishes the Best Millionaire Dating App and Official Dating Site Reviews 2015 2Health News:New Advancement in Treatment of Chronic Neck Pain 2Health News:New Advancement in Treatment of Chronic Neck Pain 3Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 2Health News:Local Solar Professional Earns Industry's Most Prestigious Certification 3Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 2Health News:High Performance Academy - Review Of Brendon Burchard's New High Performance Training Program Released 3Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3
... a heart must stop beating before death is certain, , , ... current guidelines on how long after cardiac death doctors must ... , There,s no question that organ donation saves lives, and ... to save everyone on the transplant list. However, deciding who ...
... Embraces Cutting-Edge Patient Safety ... ... a,partnership with Kahala Nui, a Life Care Retirement Community in Honolulu,Hawai,i, ... Hi,olani Care Center. Kahala Nui joins a list of,progressive healthcare facilities ...
... update expected imminently - Successfully completed ... AMEX appeal continuing TORONTO, Aug. 13 /PRNewswire-FirstCall/ - Predictive ... financial,results for the second quarter fiscal 2008 ended June 30, ... to be one of tremendous focus and,dedication in resolving some ...
... 13 Assurant, Inc. ("Assurant"),(NYSE: AIZ ), ... and services, announced today that Jane Meyer,has been ... Walker,has been appointed senior vice president, organizational development ... Both Ms. Meyer and Mr. Walker will ...
... reproductive health care services remains flat, survey finds , , ... are availing themselves of contraceptives services, such as birth ... , From 1995 to 2002, the percentage of ... from 36 percent to 41 percent, according to Jennifer ...
... BEIJING, Aug. 13 /Xinhua-PRNewswire-FirstCall/ -- Lotus,Pharmaceuticals, Inc. (OTC ... company in the People,s Republic of China,("PRC"), today ... at 10:00,a.m. Eastern Time on Monday, August 18, ... 30, 2008., Joining Dr. Zhongyi Liu, Chairman ...
Cached Medicine News:Health News:Infant Heart Transplant Controversy Continues 2Health News:Infant Heart Transplant Controversy Continues 3Health News:Infant Heart Transplant Controversy Continues 4Health News:Hoana Medical, Inc. Partners With Kahala Nui to Improve Patient Safety 2Health News:Hoana Medical, Inc. Partners With Kahala Nui to Improve Patient Safety 3Health News:Hoana Medical, Inc. Partners With Kahala Nui to Improve Patient Safety 4Health News:PreMD Reports Second Quarter Results 2Health News:PreMD Reports Second Quarter Results 3Health News:PreMD Reports Second Quarter Results 4Health News:PreMD Reports Second Quarter Results 5Health News:PreMD Reports Second Quarter Results 6Health News:PreMD Reports Second Quarter Results 7Health News:PreMD Reports Second Quarter Results 8Health News:PreMD Reports Second Quarter Results 9Health News:PreMD Reports Second Quarter Results 10Health News:PreMD Reports Second Quarter Results 11Health News:PreMD Reports Second Quarter Results 12Health News:PreMD Reports Second Quarter Results 13Health News:Assurant Announces Two Executive Appointments 2Health News:More U.S. Women Getting Birth Control Services 2Health News:Lotus Pharmaceuticals Announces Conference Call to Discuss Second Quarter 2008 Results 2
Antibiotics (Gentamicin) loaded, low viscosity bone cement for syringe use with an average setting time of approx. 7-9 Min., 41.6g of powder and 16.4g of liquid....
Antibiotics (Gentamicin) loaded, high viscosity bone cement for digital use with an average setting time of approx. 6-8 Min., 41.6g of powder and 14.4g of liquid....
... provide superior image quality and light ... camera head with a C-mount thread. ... light at the operative site while ... clarity and reliability.,The Videoscopes have completely ...
... Solitaire represents the latest in green laser technology, ... in both the operating room and clinic. Designed ... the premium 532nm photocoagulator. , ,The Solitaire is ... the flexibility to deliver up to 2.0 W ...
Medicine Products: