Navigation Links
Soligenix Receives IND Clearance from FDA to Initiate Clinical Program to Evaluate SGX942 for the Treatment of Oral Mucositis
Date:3/27/2013

ltaneous anti-inflammatory and anti-infective activity. IDRs have no direct antibiotic activity but modulate host responses, increasing survival after infections with a broad range of bacterial Gram-negative and Gram-positive pathogens, as well as accelerating resolution of tissue damage following exposure to a variety of agents including bacterial pathogens, trauma and chemo- and/or radiation-therapy.  SGX942 has demonstrated safety in a Phase 1 clinical study in healthy human volunteers and efficacy in numerous animal disease models including mucositis, colitis, skin infection and other bacterial infections.  SGX942 was developed pursuant to discoveries made by Professors B. Brett Finlay , PhD and Robert Hancock , PhD of the University of British Columbia, Canada and approximately $40 million has been put towards its development inclusive of government grants. 

About Oral Mucositis

Mucositis is the clinical term for damage done to the mucosa by anticancer therapies (e.g., radiation or chemotherapy).  It can occur in any mucosal region, but is most commonly associated with the mouth, followed by the small intestine. Mucositis affects approximately 500,000 people in the US per year and occurs in 40% of patients receiving chemotherapy. Mucositis can be severely debilitating and can lead to infection, sepsis, the need for parenteral nutrition and narcotic analgesia. The gastrointestinal damage causes severe diarrhea. These symptoms can limit the doses and duration of cancer treatment, leading to sub-optimal treatment outcomes.  The mechanisms of mucositis have been extensively studied and have been recently linked to the interaction of chemotherapy and/or radiation therapy with the innate defense system. Bacterial infection of the ulcerative lesions is now regarded as a secondary consequence of dysregulated local inflammation triggered by therapy-induced cell death, ra
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
2. Soligenix Reports First Quarter 2012 Financial Results and Highlights Recent Accomplishments
3. Soligenix Reports Second Quarter 2012 Financial Results and Highlights Recent Accomplishments
4. Soligenix Announces Issuance of US Patent for Topically Active Steroids to Treat Inflammatory Gastrointestinal Disorders
5. FDA Grants Soligenix Fast Track Designation for SGX203 for the Treatment of Pediatric Crohns Disease
6. Soligenix Reports Third Quarter 2012 Financial Results and Highlights Recent Accomplishments
7. FDA Grants Soligenix Fast Track Designation for OrbeShield(TM) for the Reduction of Mortality Associated with Gastrointestinal Acute Radiation Syndrome (GI ARS)
8. Soligenix Announces Formation of Oral Mucositis Medical Advisory Board
9. Soligenix to Present at 15th Annual BIO CEO & Investor Conference
10. PAREXEL Chief Operating Officer Dr. Mark A. Goldberg Receives Special Recognition Award
11. Leica Biosystems Receives FDA Approval for the Fully Automated Bond Oracle™ HER2 IHC System on the Leica BOND-MAX
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/20/2014)... LAKE CITY , Aug. 20, 2014 ... revolutionary mobile diagnostic platform during a special event at ... Utah , on September 5, 2014. The event, ... LiveStreamed on the ApolloDx website, www.apollodx.com .    ... transform diagnostic testing," said Jared Bauer , Co-Founder ...
(Date:8/20/2014)... LAKE WORTH, Fla. , Aug. 20, 2014  Glades ... Florida , is proud to announce its expansion into ... , which will feature an 8,000-square-foot office space and ... is currently accepting applications for 100 open positions for the ... located at 4560 Lantana Road will serve as the chain,s ...
(Date:8/20/2014)... Aug. 20, 2014   Easy Breathe , the fastest growing ... " Easy Blog " - has received more than 4.5 million ... "We are thrilled that so many people are finding our ... of Easy Breathe. "We,re committed to making sleep apnea more widely ... stay informed about sleep apnea news , troubleshooting advice ...
Breaking Medicine Technology:Glades Drugs Moves to New Corporate Headquarters, 100 Open Positions 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 2Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 3Easy Breathe Blog Emerges as the Go-To Resource for Sleep Apnea Sufferers 4
... Virtual Radiologic (vRad), a technology-enabled national radiology ... Illinois-based radiology practice serving Champaign/Urbana, Effingham, Danville ... a strategic alliance, merging Lakeland with an ... will be called Lakeland Radiology Alliance, and ...
... electromagnetic applications in the healthcare industry, HFSS™ software from ... now provide proof that a biomedical device transmitter design ... that will enable medical device developers to cut development ... (Logo: http://photos.prnewswire.com/prnh/20110127/MM38081LOGO) The FCC ruled in February ...
Cached Medicine Technology:Virtual Radiologic and Lakeland Radiologists Partner to Create Lakeland Radiology Alliance 2Virtual Radiologic and Lakeland Radiologists Partner to Create Lakeland Radiology Alliance 3FCC Approval of Finite Element Method for Biomedical Transmitters Puts ANSYS Software in the Spotlight 2FCC Approval of Finite Element Method for Biomedical Transmitters Puts ANSYS Software in the Spotlight 3FCC Approval of Finite Element Method for Biomedical Transmitters Puts ANSYS Software in the Spotlight 4
(Date:8/20/2014)... 2014 Fancyflyingfox.com, the popular online supplier ... has unveiled a new collection of 2014 military ... launched a promotion for these trendy and elegant products. ... launches the special offer to show its appreciation to ... released military ball outfits are provided with deeply discounted ...
(Date:8/20/2014)... PAINWeek, the National Conference on ... Nadelmann, JD, PhD, will deliver the Keynote Address ... and executive director of the Drug Policy Alliance, ... alternatives to the war on drugs. As a ... and internationally, he has played a pivotal role ...
(Date:8/20/2014)... Recently, UWDress.com, the distinguished wedding dress ... birthday party dresses for girls . According to ... and exquisitely handmade by experienced specialists. Now, they are ... , The company’s new items come in various styles: ... length frocks, long elegant backless gowns and so on. ...
(Date:8/20/2014)... An Elle Magazine online report dated August 13, ... Young at Every Age,” offers a set of recommendations to ... These recommendations are offered as a preventative skincare plan. ... and beyond. The first group of recommendations can be universally ... using sunscreen religiously, getting sufficient exercise and sleep, and eating ...
(Date:8/20/2014)... 2014 Today, Zane Benefits, the ... of a new eBook, Affordable Care Act 101. ... owners feel uncertain about how the ACA impacts ... bottom line. , The new eBook outlines key ... navigate their upcoming health insurance decisions. , Read ...
Breaking Medicine News(10 mins):Health News:2014 Military Ball Gowns Offered At Popular Online Store Fancyflyingfox.com 2Health News:PAINWeek Welcomes Ethan Nadelmann, JD, PhD, as Keynote Speaker at 2014 Conference 2Health News:Cheap Birthday Party Dresses for Girls Now Available at UWDress.com 2Health News:Simon Ourian, Kim Kardashian’s Doctor, On Healthy Skin Suggestions for Every Age 2
... study at Duke Univ. has shown that the surgical outcome ... as in non-diabetics. The results were published Aug. 15, 2005, ... In the largest analysis of its kind, Duke University Medical ... surgery for ankle fractures have significantly higher rates of complications ...
... research report presented in the latest BMJ said that ... motivational interviewing by midwives to help pregnant smokers quit ... the smoking habits of the mothers//. ,A third ... they should be offered intensive support to help them ...
... Aug 15. The best single predictor of happiness is ... status only follow health as per a recent study//. ... graduate student Laura Tach from Harvard University measured the ... using analysis from the 1972-2002 General Social Survey. ...
... be on constant rise, though the floodwaters seem to be receding ... Mumbai and Thane district and now the death toll stands ... the Maharashtra Directorate of Health services sources on Monday. ... persons were admitted to various hospitals in Mumbai with complaints of ...
... Bath, UK has found that Cannabinoids derived from Cannabis ... inflammatory bowel diseases like Crohn’s disease and //ulcerative colitis.,"The ... present and functioning in the lining of the gut," ... Bath, explained to Reuters Health. "There is an increased ...
... and the American Academy of Pediatrics (AAP) had recommended ... sports activity in order to prevent //mouth injuries. ... under are injured while playing sports or participating in ... and the AAP annual back-to-school health promotion, when some ...
Cached Medicine News:Health News:Ankle Fracture Surgery – Diabetics fare worse than non-diabetics 2Health News:Ankle Fracture Surgery – Diabetics fare worse than non-diabetics 3Health News:Trained Counselors Counseling Pregnant Smokers To Quit May Not Work 2Health News:Rich are happier then Poor 2Health News:233 Dead in Mumbai and Thane due to Water Borne Diseases 2Health News:Dentists Recommend Kids Use Mouthguard To Protect Them When Doing Sports 2
... is the most common cause ... 5% of pediatric visits and ... under 5 years. ImmunoSTAT! Rotatvirus ... rule in or rule out ...
The CdTOX A OIA gets the results you need without specimen extraction or instrumentation. Results are available in minutes vs hours or days for EIA or other methods. The combination of performance, ...
... and nerve block procedures, Cadwells disposable ... a precisely machined Trocar (beveled) tip ... 61-cm (24-in) lead wire. Needle is ... use only. A starter kit includes ...
... Back Relief Apron has standard ... the weight from the shoulders ... aid of a 6" wide ... strap keeps apron snug. Belts ...
Medicine Products: