Navigation Links
Soligenix Initiates Phase 1 Clinical Study with SGX203 for the Treatment of Pediatric Crohn's Disease
Date:5/15/2013

PRINCETON, N.J., May 15, 2013 /PRNewswire/ -- Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), a clinical stage biopharmaceutical company focused on developing products to treat inflammatory diseases and biodefense countermeasures where there remains an unmet medical need, announced today that it has initiated the first clinical study for development of SGX203 (oral beclomethasone 17,21-dipropionate or oral BDP) for the treatment of pediatric Crohn's disease.  The program has previously received Fast Track and Orphan Drug designations from the U.S. Food and Drug Administration (FDA) for oral BDP as a treatment for pediatric Crohn's Disease.

The objective of Study BDP-PCD-01, entitled "A Phase 1 Pharmacokinetic/Pharmacodynamic Study of Oral Beclomethasone 17,21-Dipropionate (BDP) in Healthy Adolescents and Young Adults", is to determine the pharmacokinetic (PK) and pharmacodynamic (PD) profile of oral BDP in healthy young male and female adolescents and adults. This study will enroll 24 subjects, with assessments to be completed in June 2013.

The program has been designed in collaboration with an expert in PK modeling and simulation, Jeffrey S. Barrett , PhD, FCP.  Dr. Barrett is Director of both the Laboratory for Applied PK/PD and also the Pediatric Pharmacology Research Unit at The Children's Hospital of Philadelphia. He is also Professor of Pediatrics at the University of Pennsylvania Medical School.

"There are currently no FDA approved corticosteroid therapies for pediatric Crohn's disease and we believe that SGX203 has the potential to meet an important medical need in children with this serious illness," stated Kevin J. Horgan , MD, Senior Vice President & Chief Medical Officer of Soligenix. "Data from this study will be used to refine the PK model we have established with Dr. Barrett.  The PK
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Soligenix Reports First Quarter 2013 Financial Results and Highlights Recent Accomplishments
2. Soligenix and Intrexon Pursue Melioidosis Therapy Through Worldwide Exclusive Collaboration
3. Soligenix to Present at World Vaccine Congress & Expo
4. Soligenix Receives IND Clearance from FDA to Initiate Clinical Program to Evaluate SGX942 for the Treatment of Oral Mucositis
5. Soligenix to Present at 15th Annual BIO CEO & Investor Conference
6. Soligenix Announces Formation of Oral Mucositis Medical Advisory Board
7. FDA Grants Soligenix Fast Track Designation for OrbeShield(TM) for the Reduction of Mortality Associated with Gastrointestinal Acute Radiation Syndrome (GI ARS)
8. Soligenix Reports Third Quarter 2012 Financial Results and Highlights Recent Accomplishments
9. FDA Grants Soligenix Fast Track Designation for SGX203 for the Treatment of Pediatric Crohns Disease
10. Soligenix Announces Issuance of US Patent for Topically Active Steroids to Treat Inflammatory Gastrointestinal Disorders
11. Soligenix Reports Second Quarter 2012 Financial Results and Highlights Recent Accomplishments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... , Jan. 22, 2015  ViewRay™, a privately held ... into an exclusive distributor agreement with ITOCHU Corporation (Tokyo ... therapy system for the treatment of cancer in ... system, is the world,s first and only MRI-guided radiation ...
(Date:1/22/2015)... /PRNewswire/ - Pivotal Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" or the "Company"), ... for cardiovascular disease and overall health is pleased to provide ... and its outlook for 2015 from the CEO, Mr. ... We would like to take this opportunity to share with ...
(Date:1/22/2015)... PARK, Calif. , Jan. 22, 2015 Increasing ... the continued consolidation of localization purchasing in 2015, says ... According to a recent study by market research ... chose a single-source solution for their translation and localization ...
Breaking Medicine Technology:ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7Moravia Sees Single-Sourcing as Key Localization Trend in 2015 2
(Date:1/22/2015)... La Jolla, Calif. (PRWEB) January 22, 2015 ... and Assemblymembers Susan Bonilla (D-Concord) and Kristin Olsen ... (CHI) for their leadership in advancing biotechnology, biomedical ... Mitchell, Bonilla and Olsen each received the “2014 ...
(Date:1/22/2015)... Four years since the release of their debut recording ... marriage of Avasa & Matthew Love – the duo are pleased ... release through White Swan Records on February 24, 2015. , THE ... path available to all of us to walk out of the ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 As interest in ... health care gains momentum worldwide, Rev. Eric J. Hall ... Chaplaincy Network (HCCN), will be the keynote speaker on ... in Israel’s public health system. , The conference, “Hope and ...
(Date:1/22/2015)... a new blog post explaining the importance of keeping a first ... an auto insurance policy . , Clients who driver safer ... vehicle insurance policies. The safety a vehicle offers from its driver ... this, drivers should always carry a first aid kit in their ...
(Date:12/26/2014)... 26, 2014 The US represents the largest ... In 2013, GlobalData’s forecast estimates that sales of branded therapies ... due to the high incidence of the disease, high drug ... Japan, and China. Increased sales of CRC therapies over the ...
Breaking Medicine News(10 mins):Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 2Health News:California Biomedical Community Honors Senator Holly Mitchell, Assemblymembers Susan Bonilla & Kristin Olsen 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 2Health News:HealthCare Chaplaincy CEO to Keynote Spiritual Care Summit in Israel 3Health News:Driving Safe And Other Factors That Make Auto Insurance Affordable! 2Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 2Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 3Health News:US Colorectal Cancer Drug Market Analysis and Forecast to 2023 Report Available at ReportsnReports.com 4
... After superman having enthralled the audience world over it is the ... of nutrients are ruling the roost these days.// ,Tesco has ... ,The catch is that they are a little expensive if you ... ,Likewise there are many other foods which are touted as good ...
... are wrong. In fact, they are at increased risk of ... from Britain's Mental Health Foundation (MHF) studied over 1,000 people ... feelings of stress, anxiety and depression, reported the online edition ... know that they are putting themselves at increased risk of ...
... a common assumption that the elderly patients who are ... intervention programs, till such time they come out of ... being excluded from such intervention modules. Infact, Researchers have ... in elderly patients with diabetes and the extent to ...
... of insulin that could revolutionize diabetic treatment has been rejected ... drug can be inhaled and provides an ideal alternative to ... ,Patients with both Type 1 and Type 2 diabetes ... associated with this form of insulin has been projected to ...
... patient died after a serious burn injury that occurred instantly ... treated with a flammable gel for a skin problem. Apparently, ... the fire escape. ,All other patients have expressed ... adherence to correct procedures, and are treating this incident as ...
... announced that on Tuesday tests carried out by Sudanese authorities ... flu, but the announcement did not state if the virus ... chickens were found at two farms in Sudan's Khartoum and ... Salih said, that the samples would be sent abroad for ...
Cached Medicine News:Health News:Superfoods make super healthy humans?? 2Health News:High Cost Forces NHS To Reject Inhaled Insulin 2
Less traumatic jaws offer a firm grasp while a self-retaining spring maintains hold on the needle. Use for grasping, applying endoloops, and driving needles during extracorporeal suturing....
The Optima III 45 cm line of laparoscopic hand instruments is ideal for operative laparoscopic/endoscopic procedures or when a longer instrument is needed....
The Optima III 45 cm line of laparoscopic hand instruments is ideal for operative laparoscopic/endoscopic procedures or when a longer instrument is needed....
The Optima III line of laparoscopic hand instruments provides a well-crafted set of instruments designed for strength and durability....
Medicine Products: