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Soligenix Demonstrates Positive Proof of Concept with its Proprietary Vaccine Thermostabilization Technology
Date:2/6/2012

xin, as well as its DNI rPA anthrax subunit vaccine. The underlying technology has been developed by Drs. Amber Clausi, John Carpenter and Theodore Randolph at the University of Colorado.

The World Health Organization (WHO) reports that 50% of all global vaccine doses are wasted because vaccines are not kept within required temperature ranges. Aluminum-adjuvanted vaccines usually need to be maintained between 2-8 degrees C and often times even brief excursions from this temperature range (especially those which result in freezing) necessitates the destruction of the product or the initiation of costly long-term stability programs. The savings realized from the elimination of cold chain costs and related product losses would significantly increase the profitability of vaccine products.  Elimination of the cold chain would also enhance the utility of these vaccines for emerging markets and for other applications requiring but lacking reliable cold chain capabilities. For vaccines that are intended for long term stockpiling, such as for use in biodefense or in pandemic situations, the utilization of Soligenix's thermostability technology has the potential to facilitate storage and distribution of strategic national stockpile vaccines in emergency settings.  It may also enable preparation of otherwise difficult multivalent (protective against multiple pathogens) formulations. 

About Soligenix, Inc.

Soligenix is a development stage biopharmaceutical company developing products to treat life-threatening side effects of cancer treatments and serious gastrointestinal diseases, and vaccines for certain bioterrorism agents. Soligenix's lead product, orBec® (oral beclomethasone dipropionate), is a potent, locally acting corticosteroid that has been initially developed for the treatment of acute gastrointestinal Graft-versus-Host disease (GI GVHD), a common and potentially life-threatening complication of hematopoietic
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SOURCE Soligenix, Inc.
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Related medicine technology :

1. Soligenix Announces Publication of Positive Stability Results with RiVax(TM), its Vaccine Against Ricin Toxin
2. Soligenix Announces Publication of Positive Pre-Clinical Results with RiVax(TM), Its Vaccine Against Ricin Toxin
3. Soligenix Announces Initiation of a Phase 1/2 Clinical Trial of SGX201 for the Prevention of Acute Radiation Enteritis
4. Soligenix Forms Consortium to Develop Thermostable Technology to Advance RiVax(TM) and Other Rapidly Acting Vaccines
5. Soligenix Announces Issuance of Hong Kong Patent for its LPM(TM) Oral Drug Delivery Technology
6. Soligenix Announces Publication of Positive Data Describing Protection from Mucosal and Systemic Ricin Intoxication by Intradermal RiVax™ Administration
7. Soligenix to Present at the OneMedForum Conference on Wednesday, June 30 at 2PM EDT
8. Soligenix Announces Award of $1.2 Million FDA Orphan Products Development Grant
9. Soligenix to Present at the Rodman & Renshaw Healthcare Conference on September 15, 2010 at 10AM EDT
10. Soligenix Announces Preliminary Results of its Phase 2 Clinical Trial of orBec® in the Prevention of Acute GVHD
11. Soligenix Announces Positive Preliminary Results of SGX202 in Radiation Injury
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