Navigation Links
Soligenix Announces Results From Its Phase 1/2 Clinical Trial of SGX201 for the Prevention of Acute Radiation Enteritis
Date:2/10/2012

ear to be consistent with the potential for SGX201 having efficacy for this disorder for which there is currently no available therapy."

"Radiation enteritis is a serious complication for colorectal cancer patients receiving radiation therapy that impacts their quality of life and can require treatment modification," stated William Small, Jr., MD, FACRO, FACR, FASTRO Professor and Vice Chairman, Department of Radiation Oncology, Associate Medical Director, Robert H. Lurie Comprehensive Cancer Center of Northwestern University Feinberg School of Medicine, and a Principal Investigator for the Phase 1/2 clinical study. "Based on oral BDP's proven pharmacology in treating severe gastrointestinal inflammation, SGX201 represents a potential prophylactic option that would enable physicians/patients to maintain planned treatment regimens to battle the underlying malignancy. I find these exploratory data encouraging and I look forward to continuing to work with Soligenix on the continued development of SGX201 in this area of great unmet medical need."

About Acute Radiation Enteritis

Acute radiation enteritis is caused by radiation-induced death of cells in the lining of the bowel. As bowel cells die and are not replaced, gastrointestinal toxicity develops due to an inflammatory response to dead cells and bacteria, with diarrhea, nausea, vomiting and pain prominent symptoms. The addition of chemotherapy may exacerbate the intestinal symptoms and itself cause significant toxicity. This treatment-related enteritis can result in delay or interruption of the cancer treatment. There are over 100,000 patients annually in the United States who receive abdominal or pelvic external beam radiation treatment for cancer, and these patients are at risk of developing radiation enteritis.

About SGX201

SGX201 is a time-release, oral formulation of BDP, a highly potent, topically active corticosteroid that has a local effect on inflamed
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Soligenix Announces Publication of Positive Stability Results with RiVax(TM), its Vaccine Against Ricin Toxin
2. Soligenix Announces Publication of Positive Pre-Clinical Results with RiVax(TM), Its Vaccine Against Ricin Toxin
3. Soligenix Announces Initiation of a Phase 1/2 Clinical Trial of SGX201 for the Prevention of Acute Radiation Enteritis
4. Soligenix Forms Consortium to Develop Thermostable Technology to Advance RiVax(TM) and Other Rapidly Acting Vaccines
5. Soligenix Announces Issuance of Hong Kong Patent for its LPM(TM) Oral Drug Delivery Technology
6. Soligenix Announces Publication of Positive Data Describing Protection from Mucosal and Systemic Ricin Intoxication by Intradermal RiVax™ Administration
7. Soligenix to Present at the OneMedForum Conference on Wednesday, June 30 at 2PM EDT
8. Soligenix Announces Award of $1.2 Million FDA Orphan Products Development Grant
9. Soligenix to Present at the Rodman & Renshaw Healthcare Conference on September 15, 2010 at 10AM EDT
10. Soligenix Announces Preliminary Results of its Phase 2 Clinical Trial of orBec® in the Prevention of Acute GVHD
11. Soligenix Announces Positive Preliminary Results of SGX202 in Radiation Injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... LONDON , July 11, 2014 ... ended at 4,396.20, down 0.52%, the Dow Jones Industrial Average ... 500 closed at 1,964.68, down 0.41%. The losses were broad ... in negative. The S&P 500 Health Care Sector Index ended ... advanced 2.75% in the last one month. Investor-Edge has initiated ...
(Date:7/11/2014)... 11, 2014 Show ... & Health Expo 2014 were a brand ... London , plus a ...          (Logo: http://photos.prnewswire.com/prnh/20130723/629764-a) ... )      (Photo: http://photos.prnewswire.com/prnh/20140711/696892-b ...
(Date:7/10/2014)... CLEVELAND , July 10, 2014  The U.S. ... a three-year grant to University Hospitals (UH) Case Medical ... a new national model aimed at improving care for ... Oncology Care," the project will test a unique model ... patients with late-stage disease, significant comorbidities, or demonstrated need ...
Breaking Medicine Technology:Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 2UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 3UK's Flagship Health & Safety Event Has Successful Inaugural Year in London 4University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4
... indicate early non-responders unlikely to subsequently,respond, have ... earlier change in treatment strategy, COLORADO SPRINGS, ... presented at the 2007 International Congress on,Schizophrenia ... assessed earlier than is presently thought, and,challenge ...
... Time Reduced By an Average of More ... PARK, N.C., April 02, 2007 /PRNewswire/ --,Adding ... XL 24-Hour(TM) Extended-Release Tablets to,Parkinson's patients' existing ... patients to continue,their daily activities for a ...
Cached Medicine Technology:New Data Show Early Non-Response to Antipsychotic Treatment May Be,Strong Predictor of Subsequent Non-Response for People with,Schizophrenia 2New Data Show Early Non-Response to Antipsychotic Treatment May Be,Strong Predictor of Subsequent Non-Response for People with,Schizophrenia 3New Data Show Early Non-Response to Antipsychotic Treatment May Be,Strong Predictor of Subsequent Non-Response for People with,Schizophrenia 4New Data Show Early Non-Response to Antipsychotic Treatment May Be,Strong Predictor of Subsequent Non-Response for People with,Schizophrenia 5New Data Show Early Non-Response to Antipsychotic Treatment May Be,Strong Predictor of Subsequent Non-Response for People with,Schizophrenia 6Once Daily, Extended-Release Ropinirole Improves Parkinson's,Symptoms in Patients not Optimally Controlled With Levodopa 2Once Daily, Extended-Release Ropinirole Improves Parkinson's,Symptoms in Patients not Optimally Controlled With Levodopa 3Once Daily, Extended-Release Ropinirole Improves Parkinson's,Symptoms in Patients not Optimally Controlled With Levodopa 4Once Daily, Extended-Release Ropinirole Improves Parkinson's,Symptoms in Patients not Optimally Controlled With Levodopa 5
(Date:7/11/2014)... screened positive for a history of hazardous or binge ... percent after receiving mobile phone text messages following a ... published online yesterday in Annals of Emergency Medicine ... Adult Emergency Department Patients: A Randomized Clinical Trial "). ... adults ages 18 to 24 visit ERs and up ...
(Date:7/11/2014)... 11, 2014 With the arrival of ... seeking cosmetic surgery and hair transplant procedures, up 80 ... expansive range of medical tourism destinations, the company is ... costs and achieve the look they have always ... the top name in the medical tourism industry, VisitandCare.com ...
(Date:7/11/2014)... By Steven Reinberg ... -- Stress, hostility and depression may increase the risk for ... depression seemed to raise the risk of a stroke or ... also found that stress apparently raised stroke or TIA risk ... said. A TIA is a mini-stroke caused by a temporary ...
(Date:7/11/2014)... July 11, 2014 Fadhits.com, the distinguished ... elegant assortment of lace holiday dresses . To ... are now offered at discounted prices, up to 65% ... can enjoy this special offer. , Fadhits.com is ... special occasion dresses for the global clients. All its ...
(Date:7/11/2014)... UC San Francisco shows that an "expressive therapy" ... women living with HIV disclose their health status ... safety and quality of their relationships., "Medication alone ... Edward L. Machtinger, MD, director of the Women,s ... our patients are on effective antiretroviral therapy but ...
Breaking Medicine News(10 mins):Health News:Text message medicine: Texts from the ER can reduce binge drinking 2Health News:VisitandCare.com Reports Increase in Cosmetic and Hair Transplant Procedures for Men 2Health News:VisitandCare.com Reports Increase in Cosmetic and Hair Transplant Procedures for Men 3Health News:Stress, Depression May Boost Stroke Risk, Study Finds 2Health News:Stress, Depression May Boost Stroke Risk, Study Finds 3Health News:Elegant Lace Holiday Dresses Released by Fadhits.com 2Health News:'Expressive therapy" intervention assists women living with HIV 2
... ... their products stocked in more than 10,000 retail outlets nationwide working closely with major ... ... brand Intellicig has signed an exclusive deal which will see their products stocked in ...
... , , , BEIJING , ... SVA),("Sinovac" or the "Company"), a leading China -based vaccine ... was,closed on February 2, 2010 . Sinovac received net ... and commissions and,estimated offering expenses payable by the Company, which ...
... , NASHVILLE, Tenn. , Feb. 2 ... its common stock cash dividend for the quarter ended December ... per share, is payable on March 4, 2010 ... , Healthcare Realty Trust is a real estate investment trust that ...
... PHILADELPHIA - For the first time, researchers from the ... three different degenerative brain disorders are linked by a ... Elk-1, was found in clumps of misshaped proteins that ... Huntington,s disease. "These results suggest a molecular ...
... ... accreditation to the Oakland University William Beaumont School of Medicine. , ... (Vocus) February 2, 2010 -- The Liaison ... Beaumont School of Medicine ., , , , ,The LCME is the national accrediting authority ...
... one scan is usually enough, but editorial begs to differ ... a paper in a medical journal to be accompanied by ... might be "overly simple and consequently not clinically useful." , ... 3 issue of the Journal of the American Medical ...
Cached Medicine News:Health News:Intellicig Clinches Exclusive Deal with Retail Distribution-Giant to Distribute Their Industry Leading Electronic Cigarettes 2Health News:Intellicig Clinches Exclusive Deal with Retail Distribution-Giant to Distribute Their Industry Leading Electronic Cigarettes 3Health News:Sinovac Announces Closing of Common Share Offering 2Health News:Sinovac Announces Closing of Common Share Offering 3Health News:Healthcare Realty Trust Announces Fourth Quarter Dividend 2Health News:3 brain diseases linked by toxic form of same neural protein 2Health News:Oakland University William Beaumont School of Medicine Reaches Development Milestone 2Health News:Analysis Examines Ultrasound Use for Blood Clots 2Health News:Analysis Examines Ultrasound Use for Blood Clots 3
... Bird and Cronin, ... manufacturer of Patient Footwear, ... Patient Care Products. Our ... highest quality and available ...
Perfect for use in the E.R. Stabilizes collateral ligament strains in seconds and allows hand and finger function. Made from 1/8" AliPlast™ PXE. Can be scissor trimmed....
... Slip on, warm with a ... to fit. Splint hardens as ... and reposition. Unique fiberglass knit ... polymer Straps included. Tape, 1" ...
... The Blue Line ThumStay offers thumb and ... with soft, breathable foam. Lightweight stays provide ... and can easily be contoured for proper ... with deQuervain's tenosynovitis, tendinitis, CMC joint arthritis, ...
Medicine Products: