Navigation Links
Soligenix Announces Publication of Positive Data Describing Protection from Mucosal and Systemic Ricin Intoxication by Intradermal RiVax™ Administration
Date:6/25/2010

PRINCETON, N.J., June 25 /PRNewswire-FirstCall/ -- Soligenix, Inc. (OTC Bulletin Board: SNGX) (Soligenix or the Company), a late-stage biopharmaceutical company, announced today the publication of an article in the June 2010 edition of Vaccine, which describes protection from mucosal and systemic ricin intoxication by intradermal administration of RiVax™, the Company's vaccine against ricin toxin. The article was authored by the Company's collaborators at the University of Texas Southwestern Medical Center at Dallas (UT Southwestern) where the vaccine originated. RiVax™ is currently being evaluated in Phase 1 human safety and immunogenicity trials, as well as non-human primate trials for efficacy.

The purpose of this study was to determine whether RiVax™ administered by intradermal (ID) injection would be more immunogenic and protective at lower doses. ID vaccination has several practical advantages in protecting humans due to the ease of administration, especially when using an ID gun, thereby eliminating the need for needles and subsequent needle disposal. In this publication, a comparison of ID and intramuscular (IM) vaccination with or without an aluminum salt adjuvant at several dose levels was investigated. The levels of anti-RiVax™ antibodies generated in serum as well as the ability of the vaccine to protect mice against ricin intoxication following systemic, gastric gavage or aerosol challenges were determined.

The major findings to emerge from this study are as follows:

  1. ID vs. IM administration of RiVax™ without adjuvant conferred equal protection;
  2. RiVax™ adsorbed to aluminum adjuvant was significantly better than RiVax™ alone in eliciting speci
    '/>"/>

SOURCE Soligenix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Soligenix Announces Publication of Positive Stability Results with RiVax(TM), its Vaccine Against Ricin Toxin
2. Soligenix Announces Publication of Positive Pre-Clinical Results with RiVax(TM), Its Vaccine Against Ricin Toxin
3. Soligenix Announces Initiation of a Phase 1/2 Clinical Trial of SGX201 for the Prevention of Acute Radiation Enteritis
4. Soligenix Forms Consortium to Develop Thermostable Technology to Advance RiVax(TM) and Other Rapidly Acting Vaccines
5. Soligenix Announces Issuance of Hong Kong Patent for its LPM(TM) Oral Drug Delivery Technology
6. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
7. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
8. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
9. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
10. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
11. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... 2015  Now available for sale, The Armor1 Ankle Roll ... ankle sprains by cushioning the ankle from an inversion ... the outside of any shoe type and allows the ... offering protection against sprains. With customers in physical therapy, ...
(Date:1/23/2015)... 2015 Cord Blood America, Inc. ( www.cordblood-america.com ) (OTC ...  filed a Preliminary Proxy Statement, Schedule 14A, with the U.S. ... an update for shareholders detailing why a "YES" vote to ... Dear Shareholders, As we reflect upon the 2014 ...
(Date:1/23/2015)... , Jan. 23, 2015  Mallinckrodt plc (NYSE: ... has approved a share repurchase program. The open-ended authorization ... of Mallinckrodt plc ordinary shares. "Funding ... top priorities as we continue to pursue a range ...
Breaking Medicine Technology:The Armor1 Ankle Roll Guard is the New Breakthrough Solution for Ankle Sprain Prevention! 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4
... June 28 Tolerx, Inc., a biopharmaceutical company ... by modulating T cell activity, today announced the initiation ... evaluate otelixizumab in autoimmune new-onset type 1 diabetes. The ... Therapy Evaluation For Early or New-Onset Type 1 Diabetes) ...
... 2010 , , , ... 3D Images Provide New Approach to Monitoring Bone Changes , ... Interim data from a prospective Investigator Initiated Trial (IIT),presented ... demonstrates that EVISTA(R) (raloxifene 60mg;,once-daily, distributed in 34 countries by DAIICHI SANKYO), indicated for ...
Cached Medicine Technology:Tolerx Initiates Confirmatory Phase 3 Clinical Trial, DEFEND-2, with Otelixizumab for Type 1 Diabetes 2Tolerx Initiates Confirmatory Phase 3 Clinical Trial, DEFEND-2, with Otelixizumab for Type 1 Diabetes 3Tolerx Initiates Confirmatory Phase 3 Clinical Trial, DEFEND-2, with Otelixizumab for Type 1 Diabetes 4New High-Resolution Computer Tomography Data Demonstrates EVISTA(R)'s Effect on Bone Quality in Osteoporotic Patients 2New High-Resolution Computer Tomography Data Demonstrates EVISTA(R)'s Effect on Bone Quality in Osteoporotic Patients 3New High-Resolution Computer Tomography Data Demonstrates EVISTA(R)'s Effect on Bone Quality in Osteoporotic Patients 4New High-Resolution Computer Tomography Data Demonstrates EVISTA(R)'s Effect on Bone Quality in Osteoporotic Patients 5
(Date:1/22/2015)... 22, 2015 Deer Path of Huntley ... Valentine’s Day Happy Hour from 3 p.m. to 4 p.m. on ... Parkway in Huntley, Illinois, serves adults with physical disabilities between the ... include Valentine's Day treats, games and sweetheart-themed karaoke. , For more ...
(Date:1/22/2015)... 22, 2015 Liberty University has received accreditation ... program from the Council for Accreditation of Counseling & ... Liberty’s Center for Counseling & Family Studies , is ... the university’s new School of Behavioral Sciences. Prior to the ...
(Date:1/22/2015)... The City of West Hollywood hosted a news conference on ... anniversary of the Supreme Court decision Roe v. Wade, which legalized ... the Roe vs. Wade decision and the fight to protect a ... City of West Hollywood Councilmember Abbe Land. “We need to continue ...
(Date:1/22/2015)... January 22, 2015 Gabe’s Chemo Duck Program is ... the first app ever created for kids with cancer. The Chemo ... and devices, is filled with enjoyable games to help children of ... The free app helps to keep kids entertained, educated and at ...
(Date:1/22/2015)... (PRWEB) January 23, 2015 VogueQueen is a ... affordable prices and many designers are thrilled to have it ... business announces its new collection of prom dresses for the ... to drive the strategic vision and he focuses on continuing ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2
... products. Same flavors. Fewer caloriesFORT WORTH, Texas, ... the Hispanic baking industry by becoming the ... line of 100 Calorie products. Building on ... the 100 Calorie line offers the perfect ...
... new study suggests , , MONDAY, Feb. 16 (HealthDay News) -- ... sleep it off, but they run the risk of developing ... cycle of headaches, a new study shows. , "Going to ... treat their headaches, and they rated it a very effective ...
... LLC, the nation,s leading provider of telemedicine health ... offshore medical service that connects remote workers with ... combines advanced telemedicine technology and medical services to ... Offshore rig and remote workers gain access to ...
... ARLINGTON, Texas, Feb. 16 Across the nation, countless ... executives at one North Texas healthcare company took some ... from being another victim to the economic crisis.2009 looks ... now in its 7th year. One year ago ten ...
... their electroplating, anodizing, and electropolishing plant. , ... Toccoa, ... completion of their new 16, long, 27 station aluminum anodizing line. ... works for some time now and even though the economy is ...
... screening, they say , , MONDAY, Feb. 16 ... screening and diagnostic for breast cancer, not serve as ... guidelines. , The guidelines, published Monday in the ... give needed direction for using breast MRI, a relatively ...
Cached Medicine News:Health News:Marinela USA(R) Launches 100 Calorie Product Line 2Health News:Using Sleep to Manage Headaches May Cause Insomnia 2Health News:Using Sleep to Manage Headaches May Cause Insomnia 3Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 2Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 3Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 4Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 5Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 6Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 7Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 8Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 9Health News:InPlace Medical Solutions Announces Advanced Medical Services for Offshore and Remote Locations 10Health News:Staying Healthy in 2009 2Health News:Experts Release Guidelines on Use of Breast MRI 2
... Ulti-Mist™ HME product line has the right ... to adults and from intubated patients to ... humidification for both anesthesia and critical care ... provide maximum protection for patients and staff ...
... HME product line has the right product ... adults and from intubated patients to patients ... for both anesthesia and critical care applications., ... maximum protection for patients and staff members. ...
... (HCH) capture the patient`s exhaled heat and ... gas. Small and compact, they are specially ... Depending on the tidal volume requirements, select ... ,The adult HCH is ideal for patient ...
... capture the patient`s exhaled heat and moisture ... Small and compact, they are specially treated ... on the tidal volume requirements, select either ... adult HCH is ideal for patient tidal ...
Medicine Products: