Navigation Links
Soligenix Announces Preliminary Results of its Phase 2 Clinical Trial of orBec® in the Prevention of Acute GVHD
Date:10/25/2010

py tailored to treat the GI manifestation of acute GVHD, the organ system where GVHD is most frequently encountered and highly problematic.  orBec® is intended to reduce the need for systemic immunosuppressive drugs to treat GI GVHD.  orBec® is formulated for oral administration in GVHD patients as a single product consisting of two tablets; one tablet is intended to release BDP in the proximal portions of the GI tract, and the other tablet is intended to release BDP in the distal portions of the GI tract.  Oral BDP may also have application in treating other GI disorders characterized by severe inflammation.  

In addition to issued patents and pending worldwide patent applications, orBec® benefits from orphan drug designations in the US and in Europe for the treatment of GI GVHD, as well as an orphan drug designation in the US for the prevention of acute GVHD and the treatment of chronic GI GVHD.  Orphan drug designations provide for 7 and 10 years of market exclusivity upon approval in the US and Europe, respectively.  orBec® has also received Fast Track designation from the FDA for the treatment of GI GVHD.

About GVHD

GVHD is a debilitating and painful disease.  It is a common disorder among immunocompromised cancer patients after receiving allogeneic stem cell or bone marrow transplants.  Unlike organ transplants where the patient's body may reject the organ, in GVHD it is the donor cells that begin to attack the patient's body – most frequently the gut, liver and skin.  Patients with mild-to-moderate GI GVHD typically develop symptoms of anorexia, nausea, vomiting and diarrhea.  If left untreated, GI GVHD can progress to ulcerations in the lining of the GI tract, and in its most severe form, can be fatal.

Systemic immunosuppressive agents such as prednisone, which are the current standard treatments for GVHD, are associated with high mortality rates
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Soligenix Announces Publication of Positive Stability Results with RiVax(TM), its Vaccine Against Ricin Toxin
2. Soligenix Announces Publication of Positive Pre-Clinical Results with RiVax(TM), Its Vaccine Against Ricin Toxin
3. Soligenix Announces Initiation of a Phase 1/2 Clinical Trial of SGX201 for the Prevention of Acute Radiation Enteritis
4. Soligenix Forms Consortium to Develop Thermostable Technology to Advance RiVax(TM) and Other Rapidly Acting Vaccines
5. Soligenix Announces Issuance of Hong Kong Patent for its LPM(TM) Oral Drug Delivery Technology
6. Soligenix Announces Publication of Positive Data Describing Protection from Mucosal and Systemic Ricin Intoxication by Intradermal RiVax™ Administration
7. Soligenix to Present at the OneMedForum Conference on Wednesday, June 30 at 2PM EDT
8. Soligenix Announces Award of $1.2 Million FDA Orphan Products Development Grant
9. Soligenix to Present at the Rodman & Renshaw Healthcare Conference on September 15, 2010 at 10AM EDT
10. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
11. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/22/2014)... , Sept. 22, 2014 ... the U.S. commercial launch of its foot plating system ... Paragon 28.  The GORILLA TM R3CON PLATING SYSTEM ... the Monster TM & Mini-Monster TM Screw ... Comprised of 10 interchangeable subsystems, the GORILLA TM ...
(Date:9/22/2014)... Sept. 22, 2014 The western European ... It is largely a replacement market with fewer ... mergers, acquisitions and partnerships are redefining competitive landscape ... research service provides details about revenue forecasts, unit ... trends across the country. The changing landscape makes ...
(Date:9/22/2014)... 2014 ... the addition of the  "Global Freeze Drying ... Market - Forecast to 2019"  report to ... ,The global freeze drying market was valued ... expected to reach at $2,655.9 million by ...
Breaking Medicine Technology:Paragon 28, Inc. Launches the GORILLA(TM) R3CON PLATING SYSTEM 2Automated Endoscope Reprocessor Market Trends in Western Europe 2Automated Endoscope Reprocessor Market Trends in Western Europe 3Global Freeze Drying / Lyophilization Equipment (Lab, Pilot, & Industrial) Market - Forecast to 2019 2Global Freeze Drying / Lyophilization Equipment (Lab, Pilot, & Industrial) Market - Forecast to 2019 3
... 4, 2011 Reportlinker.com announces that a new market ... Personalized Medicine - scientific & commercial aspects ... aim of personalized medicine or individualized treatment is to ... in some cases, even to design the appropriate treatment ...
... a proposed Settlement in a class action lawsuit involving ... treat a variety of medical conditions including: cancer, HIV, ... blood issues, and many other conditions.  These drugs are ... This lawsuit is not about whether these drugs ...
Cached Medicine Technology:Reportlinker Adds Personalized Medicine - Scientific & Commercial Aspects 2Reportlinker Adds Personalized Medicine - Scientific & Commercial Aspects 3Reportlinker Adds Personalized Medicine - Scientific & Commercial Aspects 4Medicare Part B Subscribers Who Made a Percentage Co-Payment for Certain Drugs May Be Able To Get a Refund from a Class Action Settlement 2
(Date:9/22/2014)... ARBOR, Mich. A surprising new study pulls back ... in health care: differences in payment and income between ... who don,t. , Contrary to perception, the research ... to favor surgeons and other procedure-performing doctors. , The ... simple difference in pay per minute explains why doctors ...
(Date:9/22/2014)... HealthDay Reporter MONDAY, Sept. ... parents are aware of online physician-rating sites, and more than ... children, according to a new national study. The findings ... further suggest that negative online ratings may dissuade parents from ... by a neighbor. Conversely, a positive online rating may ...
(Date:9/22/2014)... (September 22, 2014) South Asians living in Canada ... the rate of diabetes compared with while people, McMaster ... today in the Canadian Medical Association Journal (CMAJ ... , One of the fastest-growing ethnic groups in ... Asian people living in Canada, comprising about three percent ...
(Date:9/22/2014)... September 22, 2014. Kessler researchers have published a ... psychoeducational wellness program in people with multiple sclerosis ... mental health, perceived stress, and pain. "Development ... individuals living with MS: Description and outcomes" was ... the International Journal of MS Care ...
(Date:9/22/2014)... Two new prescription devices approved by the U.S. Food ... people with migraine headaches who don,t tolerate migraine medications ... -- the Cefaly -- is designed to prevent migraines, ... meant to be used when migraines first start, according ... looking for alternative migraine treatments. Because these devices aren,t ...
Breaking Medicine News(10 mins):Health News:Think the system for paying US doctors is rigged to favor surgeons? Study may surprise you 2Health News:Think the system for paying US doctors is rigged to favor surgeons? Study may surprise you 3Health News:Think the system for paying US doctors is rigged to favor surgeons? Study may surprise you 4Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 2Health News:Many Parents Use Online Ratings to Pick a Pediatrician, Study Finds 3Health News:Higher risk of heart disease for South Asians in Canada 2Health News:Noninvasive Devices May Help Migraines, FDA Says 2
... Feb. 16 (HealthDay News) -- Many American parents of children ... medicines to their kids despite U.S. Food and Drug Administration ... to research linking over-the-counter (or OTC) cough and cold medicines ... years and younger, the FDA said in 2008 that the ...
... A University of Minnesota research team was recently ... from the National Science Foundation,s Cyber-Enabled Discovery and ... vision algorithms that will assist with the early ... such as autism, attention deficit disorder (ADD) and ...
... TORONTO, Ont., February 16, 2011 One in five homeless ... according to a study led by St. Michael,s Hospital,s Dr. ... decade despite recommendations calling for greater improvements in prevention and ... inquest into the death of Joseph Teigesser, a homeless man ...
... Researchers from Indiana University-Purdue University Indianapolis (U.S.A) and Umea ... February 15, 2011, issue of PLoS Biology ... their DNA, known as Break-induced Replication (BIR), is up ... than normal cell repair. Accurate transmission of genetic ...
... Spanish provinces in terms of early prevention of breast cancer, ... rates, although the trend is towards the figures levelling out ... carried out by Spanish researchers, which analyses the number of ... Islands, Balearic Islands, some parts of Catalonia, Valencia and Murcia, ...
... radiation treatments for head and neck cancer fare significantly ... to a study in the February issue of the ... journal of the American Society for Radiation Oncology (ASTRO). ... and head and neck cancers has long been established, ...
Cached Medicine News:Health News:Parents Still Giving Cough, Cold Meds to Kids Under 2: Poll 2Health News:University of Minnesota researchers study the use of computer vision to diagnose mental disorders 2Health News:Death rate from tuberculosis in homeless alarmingly high: Study 2Health News:Method of DNA repair linked to higher likelihood of genetic mutation 2Health News:Study looks into evolution of breast cancer in Spain 2Health News:Smoking during radiation treatments reduces chance of overall survival 2
... Preserve your data for future generations. Most gels ... solid backing plate of our gel dryer, covering ... frame over them to hold the cellophane flat. ... frame with an open area somewhat larger than ...
... for future generations. Most gels can be dried ... of our gel dryer, covering them with wet ... to hold the cellophane flat. Tut's Tombs also ... open area somewhat larger than the gel to ...
... Slim Slab Gel Dryer accommodates large sequencing gels or ... TEFLON coated platen for long lasting durability and corrosion ... , Quick Drying Rate - large ... , Digital display of temperature and time ...
... gel dryer and oil-free vacuum pump into one ... setup. The extremely versatile gel drying system can ... and multiple mini-gels as well as drying large ... Completely Integrated Gel Drying System eliminates setup ...
Medicine Products: