Navigation Links
Soligenix Announces Preliminary Results of its Phase 2 Clinical Trial of orBec® in the Prevention of Acute GVHD
Date:10/25/2010

py tailored to treat the GI manifestation of acute GVHD, the organ system where GVHD is most frequently encountered and highly problematic.  orBec® is intended to reduce the need for systemic immunosuppressive drugs to treat GI GVHD.  orBec® is formulated for oral administration in GVHD patients as a single product consisting of two tablets; one tablet is intended to release BDP in the proximal portions of the GI tract, and the other tablet is intended to release BDP in the distal portions of the GI tract.  Oral BDP may also have application in treating other GI disorders characterized by severe inflammation.  

In addition to issued patents and pending worldwide patent applications, orBec® benefits from orphan drug designations in the US and in Europe for the treatment of GI GVHD, as well as an orphan drug designation in the US for the prevention of acute GVHD and the treatment of chronic GI GVHD.  Orphan drug designations provide for 7 and 10 years of market exclusivity upon approval in the US and Europe, respectively.  orBec® has also received Fast Track designation from the FDA for the treatment of GI GVHD.

About GVHD

GVHD is a debilitating and painful disease.  It is a common disorder among immunocompromised cancer patients after receiving allogeneic stem cell or bone marrow transplants.  Unlike organ transplants where the patient's body may reject the organ, in GVHD it is the donor cells that begin to attack the patient's body – most frequently the gut, liver and skin.  Patients with mild-to-moderate GI GVHD typically develop symptoms of anorexia, nausea, vomiting and diarrhea.  If left untreated, GI GVHD can progress to ulcerations in the lining of the GI tract, and in its most severe form, can be fatal.

Systemic immunosuppressive agents such as prednisone, which are the current standard treatments for GVHD, are associated with high mortality rates
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8

Related medicine technology :

1. Soligenix Announces Publication of Positive Stability Results with RiVax(TM), its Vaccine Against Ricin Toxin
2. Soligenix Announces Publication of Positive Pre-Clinical Results with RiVax(TM), Its Vaccine Against Ricin Toxin
3. Soligenix Announces Initiation of a Phase 1/2 Clinical Trial of SGX201 for the Prevention of Acute Radiation Enteritis
4. Soligenix Forms Consortium to Develop Thermostable Technology to Advance RiVax(TM) and Other Rapidly Acting Vaccines
5. Soligenix Announces Issuance of Hong Kong Patent for its LPM(TM) Oral Drug Delivery Technology
6. Soligenix Announces Publication of Positive Data Describing Protection from Mucosal and Systemic Ricin Intoxication by Intradermal RiVax™ Administration
7. Soligenix to Present at the OneMedForum Conference on Wednesday, June 30 at 2PM EDT
8. Soligenix Announces Award of $1.2 Million FDA Orphan Products Development Grant
9. Soligenix to Present at the Rodman & Renshaw Healthcare Conference on September 15, 2010 at 10AM EDT
10. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
11. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... PUNE, India , August 28, 2015 ... "Cancer Biomarker Market by Tumor (Breast, Lung, Prostate) Type ... Immunoassay) Application (Diagnostic, Drug Discovery, Prognostic) & Geography - ... Biomarkers Market is expected to reach around 17,689.0 Million ... the forecast period of 2015 to 2020. ...
(Date:8/28/2015)... , Aug. 28, 2015  Today, in final ... (CDC) Contact Lens Health Week, 1-800 Contacts is sharing ... found that contact lens wearers who do not properly ... risk for eye infections. Most contact ... lenses, but a clean lens case is sometimes overlooked.  ...
(Date:8/28/2015)... -- Research and Markets ( http://www.researchandmarkets.com/research/sqh7xc/investigation ... Report on China,s Ranibizumab Market, 2012-2019" report to ... approved by CFDA to treat wet age- related macular ... of Novartis, is available in the Chinese market. However, ... for the treatment of wet AMD in ...
Breaking Medicine Technology:Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 2Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 3Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 4Cancer Biomarkers Market Worth 17,689.0 Million USD by 2020 51-800 Contacts Shares Tips on How to Clean Lens Cases 2Investigation Report on China's Ranibizumab Market, 2012-2019 2
... Oct. 12, 2011 Endo Pharmaceuticals (Nasdaq: ENDP ... October 27, 2011 and will host a conference call and ... results.   David P. Holveck, president and CEO ... executive vice president of R&D, Alan Levin, executive vice president ...
... the results of a recent statewide survey, more than half ... their (parents,) prescription (Rx) medications, and one in seven parents ... not prescribed for their child. The survey was ... during a briefing at the Massachusetts State House hosted by ...
Cached Medicine Technology:Endo Pharmaceuticals to Announce Third Quarter 2011 Financial Results on October 27, 2011 2More Than Half of Massachusetts Parents Say Their Kids Have Access to Abusable Prescription Drugs in Their Homes 2More Than Half of Massachusetts Parents Say Their Kids Have Access to Abusable Prescription Drugs in Their Homes 3More Than Half of Massachusetts Parents Say Their Kids Have Access to Abusable Prescription Drugs in Their Homes 4
(Date:8/30/2015)... ... August 30, 2015 , ... InHealth Media ( http://www.inhealthmedia.com ) ... Communications Director for InHealth Media. Mr. Spector comes with a wide array ... doing on-air television, producing shows, on air-radio and media relations. , Brian ...
(Date:8/30/2015)... Boca Raton, Fl (PRWEB) , ... August 30, ... ... today that Kathleen Kall has been promoted from Administrative assistant to Executive Assistant ... communication, you’ll interact with a proven professional, focused on your goals. Kathleen ...
(Date:8/29/2015)... ... August 30, 2015 , ... ... — 1:30 p.m. – 3:00 p.m. EDT, http://www.fdanews.com/electronicinformedconsent , The simple ... digital handwritten signature. , Clinical trial sites can now use audio, ...
(Date:8/29/2015)... ... August 29, 2015 , ... Targeted therapies, made ... the lives of patients, according to a newly published report. Surviving Mesothelioma has ... full article. , The authors of the new paper focus on several ...
(Date:8/29/2015)... ... 29, 2015 , ... ProDrop Particles includes over 40 particle backdrops designed for ... unique footage that users can shrink and stretch in the Final Cut Pro X ... customize color, brightness, scale, speed, range, and flare attributes with intuitive controls found in ...
Breaking Medicine News(10 mins):Health News:InHealth Media Appoints New Global Communications Director 2Health News:NPI Appoints New Executive Assistant To CEO 2Health News:FDAnews Announces — Electronic Informed Consent for Clinical Trials: Best Practices Webinar, Sept. 15, 2015 2Health News:FDAnews Announces — Electronic Informed Consent for Clinical Trials: Best Practices Webinar, Sept. 15, 2015 3Health News:FDAnews Announces — Electronic Informed Consent for Clinical Trials: Best Practices Webinar, Sept. 15, 2015 4Health News:Top Mesothelioma Researchers Highlight Targeted Therapies in New Report, According to Surviving Mesothelioma 2Health News:FCPX Effects Developer, Pixel Film Studios, Releases ProDrop Particles. 2
... By Amanda Gardner HealthDay Reporter , THURSDAY, ... the American Southwest, experts are worried not just about ... risks both to nearby residents and to those living ... are anecdotal, people on the front lines of health ...
... use, encouraging infants and young children in preschool and ... play, and requiring child care providers to promote healthy ... curb high rates of obesity among America,s youngest children, ... The report recommends steps that should ...
... (HealthDay News) -- Strategies to encourage physical activity, healthy eating ... of obesity among infants, toddlers and preschoolers in the United ... Limiting children,s TV time is a key recommendation. ... 2 to 5 have doubled since the 1980s. About 10 ...
... 2011 A new automated sample preparation system ... platform has been developed for proteomic biomarker discovery ... Research Institute (TGen) and the Biodesign Institute at ... integrated, high-throughput system is a key tool in ...
... , THURSDAY, June 23 (HealthDay News) -- Minimally invasive ... the deep veins compared with traditional surgery, University of ... called venous thromboembolism (VTE), occur in about a quarter ... The benefits of less invasive laparoscopic surgery also include ...
... investigating how to help deaf people, who have received ... Music professor David Nicholls and Dr Rachel van ... Research (ISVR) have secured a 109,000 grant from the ... from the South of England Cochlear Implant Centre, based ...
Cached Medicine News:Health News:Smoke From Wildfires in Southwest May Be Health Hazard 2Health News:Smoke From Wildfires in Southwest May Be Health Hazard 3Health News:Policies that promote healthy eating, activity and sleep are needed to curb obesity in infants, toddlers and preschoolers 2Health News:Policies that promote healthy eating, activity and sleep are needed to curb obesity in infants, toddlers and preschoolers 3Health News:Policies that promote healthy eating, activity and sleep are needed to curb obesity in infants, toddlers and preschoolers 4Health News:Ways to Curb Childhood Obesity Outlined in U.S. Report 2Health News:Less Invasive Colon Surgery Results in Fewer Blood Clots: Study 2Health News:Helping deaf people to enjoy music again 2
The 7700 Reciprocating Saw completes the large power system with our simple twist-lock blade hub and selection of saw blades....
... 7600 Oscillating Saw offers unparalleled ... thanks to its 14.4V NiMH ... head may be rotated into ... any plane and will accept ...
... of a pistol-grip handpiece available in Pneumatic, ... range of couplers that can be used ... ,MicroAire SmartDriver. Modular Pistol-Grip instrument used ... module for drilling, pinning, cutting, and debridement. ...
... The SmartDriver System consists of a ... Battery Power, with a wide range of ... variety of orthopedic surgical applications., ,The ... and speed compared to the original Battery ...
Medicine Products: