Navigation Links
Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
Date:4/25/2012

PRINCETON, N.J., April 25, 2012 /PRNewswire/ -- Soligenix, Inc. (OTCBB: SNGX) (Soligenix or the Company), a development stage biopharmaceutical company, announced today further progress in the development of ThermoVax™, its proprietary vaccine thermostabilization technology.  Progress has been based on additional characterization of the stability of prototype vaccines that have been kept at elevated temperatures in excess of three months. These studies are being conducted as part of a continuing program to evaluate the effectiveness of vaccines designed to withstand extremes of temperature and other environmental stress conditions.  The research and development of ThermoVax™ is being supported by a $9.4 million National Institute of Allergy and Infectious Disease (NIAID) grant to Soligenix for biodefense indications against ricin toxin and anthrax exposure.

Prior results have indicated that the Company's aluminum-adjuvanted ricin toxin vaccine, known as RiVax™, retained effectiveness and potency while stored at 40 degrees Celsius for one month when combined with the ThermoVax™ technology.  Confirmatory results have now extended these initial observations to more than three months when the vaccine is kept at 40 degrees Celsius.  In contrast, liquid RiVax™ vaccine when stored at 40 degrees Celsius rapidly degraded and no longer maintained its effectiveness. This is due to the fact that the ricin A chain is normally extremely labile and sensitive to temperature, and rapidly loses its ability to induce neutralizing antibodies when exposed to temperatures higher than 8 degrees Celsius.  ThermoVax™ is able to produce stable and potent vaccine formulations by combining precise lyophilzation technology with conventional aluminum adjuvants, secondary adjuvants (for rapid onset of immunity), and protein subunits.  

The removal of water from pharmaceutical preparations by lyophilization is
'/>"/>

SOURCE Soligenix, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Soligenix Announces Publication of Positive Stability Results with RiVax(TM), its Vaccine Against Ricin Toxin
2. Soligenix Announces Publication of Positive Pre-Clinical Results with RiVax(TM), Its Vaccine Against Ricin Toxin
3. Soligenix Announces Initiation of a Phase 1/2 Clinical Trial of SGX201 for the Prevention of Acute Radiation Enteritis
4. Soligenix Forms Consortium to Develop Thermostable Technology to Advance RiVax(TM) and Other Rapidly Acting Vaccines
5. Soligenix Announces Issuance of Hong Kong Patent for its LPM(TM) Oral Drug Delivery Technology
6. Soligenix Announces Publication of Positive Data Describing Protection from Mucosal and Systemic Ricin Intoxication by Intradermal RiVax™ Administration
7. Soligenix to Present at the OneMedForum Conference on Wednesday, June 30 at 2PM EDT
8. Soligenix Announces Award of $1.2 Million FDA Orphan Products Development Grant
9. Soligenix to Present at the Rodman & Renshaw Healthcare Conference on September 15, 2010 at 10AM EDT
10. Soligenix Announces Preliminary Results of its Phase 2 Clinical Trial of orBec® in the Prevention of Acute GVHD
11. Soligenix Announces Positive Preliminary Results of SGX202 in Radiation Injury
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... 2014  Lockton Dunning Benefits, the ... the addition of Vice President Kim Foerster ... Pharmacy Consulting team, Excelsior Solutions. ... to the position.  Most recently, she worked as ... Specialty Pharmacy, where she has held various managerial ...
(Date:12/24/2014)... N.C. , Dec. 23, 2014  Endo Pharmaceuticals ... ENDP ) (TSX: ENL), and BioDelivery Sciences International, ... they have submitted a New Drug Application (NDA) for ... Drug Administration (FDA).  Buprenorphine HCl Buccal Film is under ... require daily, around-the-clock, long-term opioid treatment and for which ...
(Date:12/22/2014)... Dec. 22, 2014 Apnea Sciences ( www.apneasciences.com ... in Aliso Viejo , California.  ... the tremendous growth and worldwide expansion, a new facility ... SnoreRx, the anti snore cure have exceeded our expectations ... "We are now in 23 countries and will be ...
Breaking Medicine Technology:Kim Foerster Joins Lockton Companies 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 2Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 3Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 4Endo Pharmaceuticals and BioDelivery Sciences Announce NDA Submission for Buprenorphine HCl Buccal Film for the Management of Moderate to Severe Chronic Pain 5
... Custom Spine, a company dedicated to offering advanced spinal ... North American Spine Society,s (NASS) annual meeting being held ... a unique articulating vertebral interbody device, which consists of ... the disc space. The interbody is inserted in ...
... CardioGenics Holdings Inc. (OTC Bulletin Board: CGNH), a developer ... the IVD testing market, was featured in Medical ... article by Amanda Petersen, titled "CardioGenics aims to offer ... Yahia Gawad, MD regarding the company,s point-of-care (POC) cardiac ...
Cached Medicine Technology:Custom Spine Launches Pathway AVID and Regent ACP at NASS 2CardioGenics Holdings Inc. Featured in Medical Device Daily 2CardioGenics Holdings Inc. Featured in Medical Device Daily 3
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... Molecules from cone snail venom and African plants are being ... oral drug to treat chronic pain. , Professor David ... Bioscience have received $218,275 from the National Health and Medical ... a product available for Australians to use. , Studies ...
... severe symptom reported by middle-aged women when their periods change ... study in the April issue of the UK-based Journal of ... of Nursing, USA, spoke to 110 women entering the menopause ... at longer or shorter intervals. Their average age was 49 ...
... RuiTai International Holdings Co., Ltd. (OTC Bulletin Board: ... and distributor,of cellulose ether products in the People,s ... for the fiscal year ended December,31, 2007., ... increased 36.7% to $38.4 million -- Gross ...
... Executive brings extensive experience in both healthcare and human ... ... 16 Precyse Solutions, the leader in,driving peak performance within Health ... Corporate,Vice President of Human Resources. She joins Precyse from Pegasus,Communications where ...
... next President to focus more on improving their,standard ... of jobs overseas than making it easier for ... to the latest "America At Work" national,opinion survey ... The workplace-issues poll, based on a sampling of ...
... It may produce chemicals that protect the brain, ... -- Regular physical exercise may help protect against ... study. , People with mild cognitive impairment can ... details of conversations, events and upcoming appointments. Most, ...
Cached Medicine News:Health News:Cone snails and plants used to develop oral drug for pain 2Health News:Getting a good night's sleep is the biggest problem for women entering the menopause 2Health News:Getting a good night's sleep is the biggest problem for women entering the menopause 3Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 2Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 3Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 4Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 5Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 6Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 7Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 8Health News:China RuiTai Reports Fiscal Year 2007 Financial Results 9Health News:Precyse Solutions Appoints Karen Heisler as New Corporate Vice President, Human Resources 2Health News:Americans Want Next President to Focus More on Saving U.S. Jobs and Healthcare; Less on Immigration Reform 2Health News:Americans Want Next President to Focus More on Saving U.S. Jobs and Healthcare; Less on Immigration Reform 3Health News:Exercise Could Cut Risk of Mild Cognitive Impairment 2
The Vitatron Excellence S+ lead series are endocardial leads providing excellent reliability and optimal pacing characteristics....
The family of Passive Plus DX passive-fixation leads features a 5 mm tip, designed to increase current density and pacing impedance, and a tine fixation, offering versatility and security in lead pla...
... The IsoFlex S lead's small ... ease implantation and lower the ... smaller, more tortuous vessels. Atrial ... and fixation options combine to ...
Unipolar Atrial "J" Lead...
Medicine Products: