The researchers found significant improvements in attention deficits, daytime sleepiness, behaviors such as anxiety and shyness, and quality of life. Both the parents and children reported on quality of life using standardized questionnaires that asked about feelings, daily activities, getting along with other children, and keeping up with schoolwork.
"We found that improvements occurred even when children were only using PAP as little as three hours a night," said Dr. Marcus, who noted that higher compliance would be expected to yield greater benefits. She added that getting children to fully adhere to treatments requires a commitment by parents and family members to a behavioral plan that supports the treatments.
Dr. Marcus said that further pediatric sleep research is warranted, such as blinded studies to compare treatment to a placebo group and further investigations of neurobehavioral outcomes. "This study was the first comprehensive study of PAP use in children, so more research should be performed, but our results have encouraging implications for using this treatment in children with sleep apnea," she concluded.
Financial support for this study came from Philips Respironics, as well as from the National Institutes of Health. Co-authors with Marcus were Jerilynn Radcliffe, Ph.D., Sofia Konstantinopoulou, M.D., Suzanne E. Beck, M.D., Mary Anne Cornaglia, Joel Traylor, RPsgT, Natalie DiFeo, CRNP, Laurie R. Karamessinis, RPFT, and Paul R. Gallagher, M.A., all of The Children's Hospital of Philadelphia; and, Lisa J. Meltzer, Ph.D., previously from CHOP, now at Denver National Health, Denver, Colo.
"Effects of Positive Airway Pressure Therapy on Neurobehavioral Outcomes in Children with Obstructive Sleep Apnea," the American Journal of Respiratory and Clinical Care Medicine, published online ahead of print Feb. 10, 201
|SOURCE The Children's Hospital of Philadelphia|
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