Navigation Links
Silence Therapeutics and InteRNA Technologies Sign Collaboration to Develop Novel microRNA Therapeutics
Date:9/11/2011

a>)

InteRNA Technologies is a Dutch early-stage drug discovery and development company that develops pathway targeted cancer therapies based on the unique functions of its proprietary microRNAs ("miRNAs").

InteRNA takes an holistic approach in R&D to unravel the biological role of its proprietary miRNAs focusing on the demonstration of their function in a number of cancer indications through functional screens, using its proprietary lentiviral-based miRNA expression library, currently the largest available. This approach results in the identification of novel, "drugable" targets, providing a steady basis for further validation and drug development.

InteRNA Technologies was incorporated in December 2006 by Aglaia Oncology Fund and has established close relationships with the research groups of its founders Edwin Cuppen, PhD, and Eugene Berezikov, PhD, of the Hubrecht Institute (Utrecht, the Netherlands), leading scientific groups in the field of miRNA research. The company further has a series of R&D partnerships with Dutch- and US-based academic hospitals and research institutes.

About MicroRNAs (miRNAs)

MicroRNA (miRNA) are naturally occurring, non-coding strands of RNA that trigger the RNA interference pathway. They result from an extensive processing route in which a long RNA transcript, folded in a hairpin structure, is cleaved into short strands of approximately 22 nucleotides - the miRNA molecules.

MiRNAs regulate gene expression by controlling the efficiency of messenger RNA (mRNA) translation - the process of translating genetic information into proteins. The miRNA binds to its target sequence in mRNA transcripts, leading to translational repression or mRNA degradation. As a result, the production of the protein encoded by that particular mRNA sequence is inhibited.

So far, approximately 940 human miRNA sequences have been documented. For many of these it is not clear what genes they target. How
'/>"/>

SOURCE Silence Therapeutics Plc
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Silence Therapeutics Receives Notice of Allowance for New U.S. Patent Covering Novel Small Interfering RNA (siRNA) Delivery Technology
2. Silence Therapeutics Phase I Atu027 Data Accepted for Presentation at the American Society of Clinical Oncology 2011 Annual Meeting
3. Silence Therapeutics Issued New U.S. Patent Covering Fundamental RNA Interference Technology Currently in Several Clinical Trials
4. Silence Therapeutics Provides Year-end Update
5. Silence Therapeutics Issued New Patents Covering siRNA Sequences for RNA Interference Therapeutics
6. Silence Therapeutics and AstraZeneca Extend siRNA Development Collaboration
7. Silence Therapeutics to Merge with Intradigm Corp to Create Leading RNAi Therapeutics Company
8. Silence Therapeutics to Receive $1.9m Milestone Payment as Pfizer and Quark Commence Phase II Trial
9. Silence Therapeutics Announces Board Changes
10. Recent siRNA Research Publications Support Silence Therapeutics Combined Development Approach
11. Video: Actress and New Mom Keri Russell Joins PKIDs to Launch Silence the Sounds of Pertussis Campaign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... LOS ANGELES , Sept. 30, 2014   ... apnea shopping destination , today announced that it now ... ResMed . AirSense CPAPs are the first sleep apnea ... makes it simple and easy to track and share ... the overall effectiveness of their CPAP therapy.  In addition, ...
(Date:9/30/2014)... BRUNSWICK, N.J., Sept. 30, 2014 The ... Kessler Foundation and New Jersey Health Foundation (NJHF) ... and patient care programs has been announced by ... officer of Kessler Foundation and James M. ... "The experience of New Jersey Health ...
(Date:9/30/2014)... -- The Eastern European medical device industry is in ... as new medical-device manufacturers are constantly trying to penetrate ... to reduce the cost incurred for placing their products ... effective means to achieve this target. This research service ... and provides profiles of key distributors in ...
Breaking Medicine Technology:Easy Breathe Now Offers World's First "Smart" CPAP Device to Treat Sleep Apnea 2Easy Breathe Now Offers World's First "Smart" CPAP Device to Treat Sleep Apnea 3Easy Breathe Now Offers World's First "Smart" CPAP Device to Treat Sleep Apnea 4Kessler Foundation Partners with New Jersey Health Foundation To Start Innovative Companies To Change the Lives of People with Disabilities 2Medical Technologies Distributor Profiles in Eastern Europe 2Medical Technologies Distributor Profiles in Eastern Europe 3
... DIEGO, Aug. 28 Vical Incorporated,(Nasdaq: VICL ... subject in its,Phase 1 trial of the company,s ... placebo-controlled trial will,evaluate safety, tolerability and immune responses ... 45 at two U.S. clinical sites. "We ...
... such ... infectious-disease outbreaks, SEATTLE, Aug. 28 In ... Fred,Hutchinson Cancer Research Center confirm that the avian influenza A ... within a family in,Indonesia. The findings, by biostatistician Ira M. ...
Cached Medicine Technology:Vical Begins Phase 1 Trial of DNA Vaccine Against H5N1 Pandemic Influenza 2Vical Begins Phase 1 Trial of DNA Vaccine Against H5N1 Pandemic Influenza 3Vical Begins Phase 1 Trial of DNA Vaccine Against H5N1 Pandemic Influenza 4Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006 2Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006 3Study Confirms Limited Human-To-Human Spread of Avian-Flu Virus in Indonesia in 2006 4
(Date:9/30/2014)... Las Vegas, NV (PRWEB) September 30, 2014 ... Marshall as a free introduction to SurvivalLife.com along with a ... has caught the attention of Shane Michaels, prompting an investigative ... the most well-known people in the survival and preparation niche, ... with all of the great classes and survival products that ...
(Date:9/30/2014)... Vegas, NV (PRWEB) September 30, 2014 ... is helping people perform better in and out of the ... and memory has caught the attention of Shane Michaels, prompting ... day-to-day grind, fatigue is the reason most people simply just ... whether that means staying focused at work, getting the motivation ...
(Date:9/30/2014)... 30, 2014 VisitandCare.com reports ... has gone up more than 79 percent in 2014, ... company also reported total revenue tripled for its entirety ... company’s professional strategy has allowed them to partner with ... for patient comfort and privacy — with state-of-the-art surgical ...
(Date:9/30/2014)... September 30, 2014 Hospice & ... annual “In Celebration” gala, honoring three outstanding individuals ... of striving to provide extraordinary and dignified comfort, ... a serious or life-limiting illness. , The event ... Rye, NY and recognized William (Bill) J. McGuinness, ...
(Date:9/30/2014)... Regenerative Medicine Solutions (RMS) is set to open ... RMS welcomes the launch of an entirely new facility, ... new treatment center for the Lung Institute. , ... Nashville, the hope is to bring awareness to those ... undiagnosed. With Nashville being a hub for medical technology, ...
Breaking Medicine News(10 mins):Health News:EverStryke: Review Exposes Joe Marshall’s Permanent Match Survival Product 2Health News:Elevate: Review Exposes Blue Star Nutraceutical’s Latest Supplement for Ultimate Brain Function, Focus, and Energy 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 2Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 3Health News:VisitandCare.com Announces Record Demand for Plastic Surgery in Turkey 4Health News:Hospice & Palliative Care of Westchester Honors Outstanding Individuals at Annual ‘In Celebration’ Gala 2Health News:Regenerative Medicine Solutions Expanding 2
... have covered one-third of the country's children in a ... than 11 million children in 1,301 counties of central ... hepatitis B, said Jiang Zuojun, the Vice-Minister for Health. ... their pace to reach the remaining two-thirds by the ...
... incidence of breast cancer at Brisbane's ABC headquarters at Toowong ... ,ABC managing director Mark Scott said that Dr Joanne Aitken ... by Dr Bruce Armstrong. ,Mr Scott added that ... alongside the panel. ,The review panel was established ...
... The British government's drug watchdog has warned yesterday that the doctors ... bipolar disorder in spite of it being one of the most ... are waiting on an average for eight years to be accurately ... almost 20 years of ill health, of which they might not ...
... poll that was conducted by the nursing union of the ... and harassment a continuing problem in// healthcare. ,Stating ... have suffered abuse from fellow staff and managers over the ... those bullied had wanted changes in their work so as ...
... Industry (ABPI) and the BioIndustry Association (BIA) recommended new ... with extreme care and caution while testing pioneering drugs. ... March left six volunteers in the state of coma. ... The new drug was tested at the Parexel trial ...
... studies shows that alternative and complementary therapies may have ... menopause.// The review article is published in the July ... the JAMA/Archives journals. ,Twenty-five million women will ... of them will experience hot flashes, night sweats, vaginal ...
Cached Medicine News:Health News:Breast Cancer Review Panel Adds Two Experts 2Health News:Bipolar Disorder Not Being Accurately Diagnosed By Doctors In UK 2Health News:Alternative Therapies May Not Ease Menopause Symptoms 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: