Navigation Links
Silence Therapeutics Signs Collaboration with miRagen Therapeutics to Evaluate Delivery of Novel microRNA-based Therapeutics
Date:1/9/2012

LONDON, January 9, 2012 /PRNewswire/ --

- Third collaboration to investigate the potential application of Silence's proprietary RNAi delivery technologies in the development of novel microRNA-based therapeutics

Silence Therapeutics plc (AIM: SLN) ("Silence"), a leading RNA interference (RNAi) therapeutics company, announces that it has signed an agreement with miRagen Therapeutics, Inc. ("miRagen"), to assess the delivery potential of Silence's proprietary DBTC delivery system with miRagen's novel microRNA- (miRNA-) based therapeutics. MiRagen is a pre-clinical stage biopharmaceutical company founded to develop innovative miRNA-based therapeutics for the treatment of cardiovascular and muscle disease.

Under the terms of the agreement, miRagen will provide Silence with specific miRNA sequences, which Silence will formulate with its proprietary DBTC delivery system in order to develop multiple candidate drugs. MiRagen will undertake in vitro and in vivo studies of the candidate drugs developed under the agreement and select lead candidates for further evaluation. Financial terms of the collaboration are not disclosed.

DBTC is a proprietary RNAi delivery system developed by Silence. It is a novel lipid-based formulation that functionally delivers short interfering RNA (siRNA) to liver endothelial cells, hepatocytes and other liver cell types with high efficiency.


SOURCE Silence Therapeutics Plc
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Silence Therapeutics Signs siRNA Delivery Collaboration With Top 10 Pharma Company
2. Silence Therapeutics Announces Issuance of Japanese Patent for Screening Therapeutics Against Key Pathway Associated with Cancer and Other Diseases
3. Silence Therapeutics and InteRNA Technologies Sign Collaboration to Develop Novel microRNA Therapeutics
4. Silence Therapeutics Receives Notice of Allowance for New U.S. Patent Covering Novel Small Interfering RNA (siRNA) Delivery Technology
5. Silence Therapeutics Phase I Atu027 Data Accepted for Presentation at the American Society of Clinical Oncology 2011 Annual Meeting
6. Silence Therapeutics Issued New U.S. Patent Covering Fundamental RNA Interference Technology Currently in Several Clinical Trials
7. Silence Therapeutics Provides Year-end Update
8. Silence Therapeutics Issued New Patents Covering siRNA Sequences for RNA Interference Therapeutics
9. Silence Therapeutics and AstraZeneca Extend siRNA Development Collaboration
10. Silence Therapeutics to Merge with Intradigm Corp to Create Leading RNAi Therapeutics Company
11. Silence Therapeutics to Receive $1.9m Milestone Payment as Pfizer and Quark Commence Phase II Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)... , 11. Juli 2014  Dilon ... für die molekulare Bildgebung, einschließlich molekularer ... die CE-Zulassung für sein Navigator ® ... Dilon das Produkt jetzt europaweit vertreiben. ... Großteil der europäischen Länder ausgedehnt und ...
(Date:7/10/2014)... Calif. , July 10, 2014  Breg, ... and services, has launched the FreeRunner™ knee brace ... who suffer from patella mal-tracking return to active ... differently than other braces, providing support when patients ... normally when they don,t. Patellofemoral issues ...
(Date:7/10/2014)... July 10, 2014  RESMED INC. (NYSE: RMD ... and fiscal year ended June 30, 2014 results on Thursday, ... close. A press release with ResMed,s results will be issued ... host a webcast to discuss operating results and future outlook. ... 1:30 p.m. US Pacific Time and the live webcast of ...
Breaking Medicine Technology:Dilon erhält CE-Zulassung für sein Navigator-Gamma-Sondensystem 2Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2
... BioTrends Research Group, Inc. recently published its ... is based on online survey ... radiologists and interventional nephrologists). It provides an in-depth view ... patterns related to both vascular access placement and maintenance. ...
... Aug. 24 Sunridge International (OTC Bulletin Board: ... next month to have meetings with key brokers and funds. ... to our company,s technology, and to facilitate funding for Sunridge ... "Now is a good time for this project," states G. ...
Cached Medicine Technology:Latest BioTrends Report Provides Comprehensive Market Landscape of the Dialysis Vascular Access Market 2
(Date:7/11/2014)... New York (PRWEB) July 11, 2014 ... ) , filed against Johnson & Johnson’s Ethicon ... Bernstein Liebhard LLP notes that the Texas Attorney ... the company’s marketing of surgical mesh products used ... incontinence. According to a report from kens5.com, the ...
(Date:7/11/2014)... Dennis Thompson HealthDay Reporter ... born with HIV who was thought to be cured by ... showing detectable levels of the AIDS-causing virus in her bloodstream, ... nearly 4 years old, had remained virus-free even though she ... Doctors had hoped her remission would open the door to ...
(Date:7/11/2014)... 2014 The report, “Specialty Synthetic ... & Geography - 2018,” defines and segments the ... an analysis and forecast of the volumes and ... (Para aramids, meta aramids, UHMW Polyethylene, carbon fiber, ... fiber, PBI fiber, PBO fiber, and liquid crystal ...
(Date:7/11/2014)... (PRWEB) July 11, 2014 ... least $50 billion in fuel costs now ... The current GHG standards are ... taken it upon themselves to install new ... , 1.    Idle reduction technologies , 2.    Efficient driveline ...
(Date:7/11/2014)... 2014 Ticket Down is a reliable ... . When it comes to the summer concert schedule, it ... Georgia native is one of the biggest names in country music ... is currently out on his “That’s My Kind of Night” tour ... tour will be making through the rest of the summer and ...
Breaking Medicine News(10 mins):Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 2Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 3Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 4Health News:Mississippi Girl Thought Cured of HIV Shows Signs of Infection 2Health News:Mississippi Girl Thought Cured of HIV Shows Signs of Infection 3Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 2Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 3Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 4Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 2Health News:LeaseQ Agrees the Latest Round of Greenhouse Gas Rules Could Increase the Cost of Truck Acquisition and Maintenance 3Health News:Luke Bryan Ticket Prices Slashed at Concord Pavilion 2Health News:Luke Bryan Ticket Prices Slashed at Concord Pavilion 3
... Set to Take Up Bill Which Includes Grants to,Train ... People,with Hearing Loss, VIENNA, Va., April 21 ... David Wu, D-Oregon, a,member of the House Subcommittee on ... in conference and vote to approve the,College Opportunity and ...
... suggests that teens may get addicted and relapse more ... motivated by drug-related cues. This conclusion has been reached ... a powerfully addicting stimulant were more likely ... it. That learned association endured: Even after experimenters ...
... of Funds in Ohio Sets Dangerous Precedent, ... preserve Ohio,s tobacco settlement dollars for their originally ... Franklin County Court of,Common Pleas for permission to ... funds, wisely dedicated by the State to,tobacco prevention ...
... leadership in premium and specialty paper market, ... that Boise BEWARE, its anti-copy/anti-scan paper, complies,with federal ... two tamper-resistant features. According to the federal mandate,for ... three,criteria by April 1. Medicaid prescription papers must ...
... April 21 NBTY, Inc. (NYSE:,NTY) (http://www.NBTY.com ), ... announced it will web cast a conference call,to review ... http://www.nbty.com on Friday, April 25, 2008 at 8:30 ... second quarter will be issued at 4:30 PM,(ET) on ...
... The National Council on Disability,(NCD) today ... Program,Performance Indicators,( http://www.ncd.gov/newsroom/publications/2008/Indicators_Report.html ),calling on the Federal ... federal data,describing the status of Americans with ... of a year-long effort. It describes what ...
Cached Medicine News:Health News:NCRA Urges Congressman David Wu to Approve in Conference the Higher Education Reauthorization Bill Providing Closed Captioning for 30 Million Deaf and Hard-of-Hearing Americans 2Health News:Rat study suggests why teens get hooked on cocaine more easily than adults 2Health News:Rat study suggests why teens get hooked on cocaine more easily than adults 3Health News:American Legacy Foundation Steps Forward to Fight For, Safeguard Ohio's Tobacco Settlement Dollars 2Health News:American Legacy Foundation Steps Forward to Fight For, Safeguard Ohio's Tobacco Settlement Dollars 3Health News:American Legacy Foundation Steps Forward to Fight For, Safeguard Ohio's Tobacco Settlement Dollars 4Health News:Boise(R) BEWARE(R) Meets April 1 Federal Medicaid Guidelines Requiring Tamper-Resistant Prescription Paper 2Health News:Boise(R) BEWARE(R) Meets April 1 Federal Medicaid Guidelines Requiring Tamper-Resistant Prescription Paper 3Health News:NBTY to Web Cast Fiscal Second Quarter Conference Call 2Health News:National Council on Disability Recommends Improving Federal Data Describing the Status of Americans with Disabilities 2Health News:National Council on Disability Recommends Improving Federal Data Describing the Status of Americans with Disabilities 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: