Navigation Links
Silence Therapeutics Receives Notice of Allowance for New U.S. Patent Covering Novel Small Interfering RNA (siRNA) Delivery Technology
Date:8/3/2011

LONDON, August 3, 2011 /PRNewswire/ --

Silence Therapeutics plc (AIM: SLN) ("Silence" or the "Company"), a leading global RNA interference (RNAi) therapeutics company, announces that the United States Patent and Trademark Office has issued the Company a notice of allowance on a patent application directed to the fundamental technology involved in AtuPLEX™, one of Silence's proprietary small interfering RNA (siRNA) delivery systems. The allowable subject matter is directed to AtuFect, the specific proprietary lipid that serves as the basis for the AtuPLEX delivery system, and provides proprietary protection for one of the RNAi industry's most clinically advanced and promising delivery technologies. These claims will cover the delivery system incorporated in Silence's lead clinical compound, Atu027, as well as a number of the Company's other RNAi therapeutic candidates.

"This is a highly valuable patent. Not only does it provide direct protection for AtuPLEX, one of the most advanced and exciting solutions addressing the challenge of delivering siRNAs, but also adds key layers of protection for our pipeline of RNAi therapeutics, including our lead RNAi therapeutic candidate, Atu027," said Max Herrmann, Chief Financial Officer of Silence Therapeutics."This notice of allowance follows the recent presentation of data from our ongoing clinical study of Atu027 at the 2011 American Society of Clinical Oncology conference which showed that the treatment, and therefore the AtuPLEX delivery technology, is safe and well-tolerated in all patients."

At the 2011 American Society of Clinical Oncology annual meeting, Silence presented interim Phase I clinical study results that showed promising antitumor activity associated with Atu027, as well as demonstrating that the treatment is well tolerated with no observed dose-limiting toxicities or evidence of cytokine activation. Favorable pharmacokinetic
'/>"/>

SOURCE Silence Therapeutics Plc
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Silence Therapeutics Phase I Atu027 Data Accepted for Presentation at the American Society of Clinical Oncology 2011 Annual Meeting
2. Silence Therapeutics Issued New U.S. Patent Covering Fundamental RNA Interference Technology Currently in Several Clinical Trials
3. Silence Therapeutics Provides Year-end Update
4. Silence Therapeutics Issued New Patents Covering siRNA Sequences for RNA Interference Therapeutics
5. Silence Therapeutics and AstraZeneca Extend siRNA Development Collaboration
6. Silence Therapeutics to Merge with Intradigm Corp to Create Leading RNAi Therapeutics Company
7. Silence Therapeutics to Receive $1.9m Milestone Payment as Pfizer and Quark Commence Phase II Trial
8. Silence Therapeutics Announces Board Changes
9. Recent siRNA Research Publications Support Silence Therapeutics Combined Development Approach
10. Video: Actress and New Mom Keri Russell Joins PKIDs to Launch Silence the Sounds of Pertussis Campaign
11. Actress and New Mom Keri Russell Joins PKIDs to launch Silence the Sounds of Pertussis Campaign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)...  Pete Rose, baseball,s all-time hits leader, is the new spokesperson ... Ducere Pharma has announced. "Pete,s a Hall of ... him on board with Myoflex," said Ducere Pharma Chief Executive ... who is known across all generations. The passion and intensity ...
(Date:1/23/2015)... VEGAS , Jan. 23, 2015 Cord Blood America, ... ) ("CBAI" or the "Company")  filed a Preliminary Proxy Statement, ... www.sec.gov ) today, and provides an update for shareholders detailing ... shares is requested. Dear Shareholders, As ...
(Date:1/23/2015)... BOSTON , January 23, 2015 ... company, is delighted to announce that the Malcolm Campbell ... Miles Congreve (Vice President of Chemistry), Fiona Marshall ... (Chief Executive Officer and co-founder) for the seminal contributions ...
Breaking Medicine Technology:Pete Rose bets on Myoflex to relieve aches and pains 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 2Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 3Heptares Scientists to Receive the Malcolm Campbell Memorial Prize for 2015 in Recognition of Their Outstanding Contribution to GPCR Drug Discovery 4
... Feb. 16, 2012  OnSiteRx®, Inc. ( http://www.onsiterx.com ), parent ... Covenant Health Network, announces today that they have successfully ... in a long-term care facility in the state of ... can increase patient safety and lower medication cost," states ...
... 16, 2012  Idenix Pharmaceuticals, Inc. (NASDAQ: IDIX ) ... the fourth quarter and year end 2011 on Thursday, February ... Idenix management will host a conference call at 4:30 p.m. ... financial results for the fourth quarter and year end 2011 ...
Cached Medicine Technology:OnSiteRx® Launches First for Arizona: Automated Drug Dispensing in Nursing Home 2
(Date:1/23/2015)... 2015 Hastings and Hastings, a law firm ... record number of legal representation client review requests for slip ... a steady rise in the number of slip and fall ... throughout the Valley. With that said, a large number of ... an experienced law firm. Hastings and Hastings is a personal ...
(Date:1/22/2015)... January 22, 2015 Liberty University has received ... program from the Council for Accreditation of Counseling ... of Liberty’s Center for Counseling & Family Studies , ... of the university’s new School of Behavioral Sciences. Prior to ...
(Date:1/22/2015)... 2015 Woodloch Pines, an all-inclusive family ... by TripAdvisor as the number one best large hotel for ... the world for their annual Travelers’ Choice Awards. , ... The website is home to millions of unbiased and honest ...
(Date:1/22/2015)... VogueQueen is a seasoned and trusted leader who consistently ... thrilled to have it lead the wedding dress industry into ... prom dresses for the global market. , “The CEO of ... he focuses on continuing the goal of operational excellence and ...
(Date:1/22/2015)... Minn. (PRWEB) January 22, 2015 Blue Cross ... those Minnesotans who exemplify what it means to “Live Fearless.” ... chance for people to share their stories about how they ... or simply inspired others by living in the moment. By ...
Breaking Medicine News(10 mins):Health News:Hastings and Hastings Reports a Record Number of Client Review Requests for Slip and Fall Accidents in 2014 2Health News:Liberty University's Resident Master’s Counseling Program Receives CACREP Accreditation 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:VogueQueen Unveils New Designs of Prom Dresses for 2015 2Health News:Blue Cross and Blue Shield of Minnesota to Showcase “Faces of Fearless” 2
... health degree careers and the alternative medicine ... as holistic health fields demonstrate continued growth. ... career site and school directory, recently launched ... reflexology career resource centers to help prospective ...
... Spectrum - a leading FDA software development company - provides medical ... their latest free technical report, available now. , ... ... leading FDA software development company Full Spectrum informs ...
... Therapeutics, Inc.,(Nasdaq and MTA: CTIC) announced today that the ... were,presented at the American Society of Hematology (ASH) 50th ... In one presentation, the Italian Cooperative ... of single dose Zevalin as sole initial treatment in,15 ...
... BEDFORD, Ohio, Dec. 8 Ben Venue Laboratories, ... 2008 Governor,s Award for Outstanding,Achievement in Environmental Stewardship ... Ohio Environmental Protection Agency on December 3, 2008.,The ... and safety,management system that strives to promote a ...
... for people living with HIV/AIDS. , ... Dakar, Senegal ... AIDS Day , global health activists gathered for the International Conference ... 6,000 people from 163 countries signed a petition demanding insecticide-treated nets ...
... NEW YORK, Dec. 8 Duane Reade Holdings, Inc. today ... Vice President of Pharmacy Operations effective December 1, 2008. ... Executive Officer. His appointment adds value and expertise to ... the appointments of several other senior executives. , ...
Cached Medicine News:Health News:Natural Healers Researches Natural Health Careers to Make the Prospective Holistic Health Students' Job Easier 2Health News:Natural Healers Researches Natural Health Careers to Make the Prospective Holistic Health Students' Job Easier 3Health News:Aimed at Medical Device Makers, FDA Software Development Company Full Spectrum Releases Free Technical Report on Software Protection Technology 2Health News:Three Italian Multicenter Studies Report High (>70%) Rates of Complete Remission (CR) Utilizing Zevalin Radio-Immunotherapy (RIT) in Treatment of Newly Diagnosed or Relapsed or Refractory Non-Hodgkin's Lymphoma 2Health News:Three Italian Multicenter Studies Report High (>70%) Rates of Complete Remission (CR) Utilizing Zevalin Radio-Immunotherapy (RIT) in Treatment of Newly Diagnosed or Relapsed or Refractory Non-Hodgkin's Lymphoma 3Health News:Three Italian Multicenter Studies Report High (>70%) Rates of Complete Remission (CR) Utilizing Zevalin Radio-Immunotherapy (RIT) in Treatment of Newly Diagnosed or Relapsed or Refractory Non-Hodgkin's Lymphoma 4Health News:Three Italian Multicenter Studies Report High (>70%) Rates of Complete Remission (CR) Utilizing Zevalin Radio-Immunotherapy (RIT) in Treatment of Newly Diagnosed or Relapsed or Refractory Non-Hodgkin's Lymphoma 5Health News:Ben Venue Laboratories, Inc. Named Recipient of the Governor's Award for Outstanding Achievement in Environmental Stewardship 2Health News:Ben Venue Laboratories, Inc. Named Recipient of the Governor's Award for Outstanding Achievement in Environmental Stewardship 3Health News:Ben Venue Laboratories, Inc. Named Recipient of the Governor's Award for Outstanding Achievement in Environmental Stewardship 4Health News:Thousands Sign Petition for Action on HIV/AIDS and Malaria 2Health News:Thousands Sign Petition for Action on HIV/AIDS and Malaria 3Health News:Thousands Sign Petition for Action on HIV/AIDS and Malaria 4Health News:Duane Reade Holdings, Inc. Further Strengthens Management Team With Addition of Frank Scorpiniti, SVP, Pharmacy Operations 2Health News:Duane Reade Holdings, Inc. Further Strengthens Management Team With Addition of Frank Scorpiniti, SVP, Pharmacy Operations 3
All welded construction for strength and durability. Choice of stainless steel or chrome plated models....
All welded construction for strength and durability. Choice of stainless steel or chrome plated models....
All welded construction for strength and durability. Choice of stainless steel or chrome plated models....
Ideal for surgical procedures, these portable stands fit into tight areas for easy instrument access. Easy placement over patient....
Medicine Products: