Navigation Links
Significant potential of late- and mid-stage Novartis hematology portfolio to be showcased at upcoming ASH meeting
Date:12/2/2009

age was 600 mg/day), and is more common in the elderly.

Severe congestive heart failure and left ventricular dysfunction have occasionally been reported. Most of the patients with reported cardiac events have had other comorbidities and risk factors, including advanced age and previous medical history of cardiac disease. Patients with cardiac disease or risk factors for cardiac failure should be monitored carefully, and any patient with signs or symptoms consistent with cardiac failure should be evaluated and treated.

Hepatotoxicity, occasionally severe, may occur. Assess liver function before initiation of treatment and monthly thereafter or as clinically indicated. Monitor liver function when combined with chemotherapy known to be associated with liver dysfunction. A 25% decrease in the recommended dose should be used for patients with severe hepatic impairment.

Patients with moderate renal impairment (CrCL = 20-39 mL/min) should receive a 50% decrease in the recommended starting dose, and future doses can be increased as tolerated. Doses greater than 600 mg/day are not recommended in patients with mild renal impairment (CrCL = 40-59 mL/min). For patients with moderate renal impairment, doses greater than 400 mg/day are not recommended. Gleevec should be used with caution in patients with severe renal impairment.

In the newly diagnosed CML trial, 2% of patients had (NCI Grades 3/4) hemorrhage.

There have also been reports, including fatalities, of cardiac tamponade, cerebral edema, acute respiratory failure, and gastrointestinal (GI) perforation.

Bullous dermatologic reactions (eg, erythema multiforme and Stevens-Johnson syndrome) have also been reported. In some cases, the reaction recurred upon rechallenge. Several postmarketing reports describe patients able to tolerate the reintroduction of Gleevec at a lower dose with or without concomitant corticosteroids or antihistamines following resol
'/>"/>

SOURCE Novartis
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

Related medicine technology :

1. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
2. DEFLUX(R) Significantly Reduces Urinary Tract Infections in Children With Vesicoureteral Reflux
3. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
4. Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)
5. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
6. Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent
7. Phase III Clinical Trial in Newly Diagnosed Multiple Myeloma Stopped Early Due to Highly Significant Efficacy Advantage of VELCADE(R) (Bortezomib) for Injection Based Therapy Across All Endpoints
8. Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
9. DOV 21,947 Demonstrates Significant Body Weight and BMI Reductions in Drug- Compliant Subjects in Phase Ib Clinical Study
10. FASgen Announces Significant Milestone in Its Cancer Drug Development Program
11. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/28/2014)... 2014  Houston dentist , Dr. ... treatment with Invisalign. With access to this increasingly ... teeth straightened without feeling self-conscious in the process. ... other types of braces, but patients who choose ... to better support for their oral health and ...
(Date:7/28/2014)... , 28 luglio 2014 ResMed (NYSE: ... prodotti per la cura dei disturbi respiratori del sonno ... avuto un,ingiunzione permanente in Germania contro il produttore Taiwanese ... la vendita di apparecchiature da indossare in testa, che ... le maschere 220. La sentenza della Corte Regionale Distrettuale ...
(Date:7/28/2014)... 2014 OmPrompt gab ... £ investiert hat, um die weltweite Nachfrage ... und Logistikbranche zu erfüllen. Albion wird Teil ... http://photos.prnewswire.com/prnh/20140728/697982 ) In ... beschleunigtes Wachstum mit Investitionen in seine Plattform, ...
Breaking Medicine Technology:Houston Cosmetic Dentist, Dr. Behzad Nazari, Now Offers Orthodontic Treatment with Invisalign 2ResMed riceve un'ingiunzione permanente contro APEX in Germania, continua a far valere i propri diritti per i brevetti in Europa 2OmPrompt erhält Finanzierung für Marktexpansion von Kundenautomatisierungsmanagement 2
(Date:7/28/2014)... Medicine (BUSM) report variants in a new gene, PLXNA4, ... (AD). The discovery of this novel genetic association may ... specifically. These findings appear in the Annals of ... dementia affecting 5.4 million Americans including 13 percent of ... percent of people age 85 and older. Genetic factors ...
(Date:7/28/2014)... WA (PRWEB) July 28, 2014 ... consulting and care management organizations, has published a ... low-cost approach to engaging patients and families in ... environments at multiple hospitals, the toolkit provides a ... huddle” with patients and their families early in ...
(Date:7/28/2014)... America Carotenoids & Antioxidants Market report defines and segments the ... forecast of revenue. This market is estimated to grow from ... at a CAGR of 7.1% from 2013 to 2018. , ... Antioxidants Market report to get an idea of the in-depth ... in the market, and is supported by various tables and ...
(Date:7/28/2014)... MONDAY, July 28, 2014 (HealthDay News) -- People with ... for obesity and diabetes, a new study suggests. ... that brown fat actually improves insulin sensitivity, blood sugar ... for overweight and obese people," Labros Sidossis, a professor ... at the University of Texas Medical Branch at Galveston, ...
(Date:7/28/2014)... 2014A two-step decision tree analysis, incorporating Donabedian,s model, ... the many available quality standards, guidelines, recommendations and ... international quality standards for radiation therapy, according to ... of Practical Radiation Oncology (PRO), the ... for Radiation Oncology (ASTRO). , Guidelines, recommendations and ...
Breaking Medicine News(10 mins):Health News:Researchers identify potential biomarker for AD 2Health News:Patient Engagement in Hospital Infection Control: Online Toolkit Provides a New Solution 2Health News:North America Carotenoids & Antioxidants (Nutraceuticals) Market is Expected to Reach $812.7 Million in 2018 - New Report by MicroMarket Monitor 2Health News:North America Carotenoids & Antioxidants (Nutraceuticals) Market is Expected to Reach $812.7 Million in 2018 - New Report by MicroMarket Monitor 3Health News:North America Carotenoids & Antioxidants (Nutraceuticals) Market is Expected to Reach $812.7 Million in 2018 - New Report by MicroMarket Monitor 4Health News:Healthy 'Brown Fat' May Cut Odds for Obesity, Diabetes 2Health News:Two-step decision tree analysis helps inform updates of RT best practices, quality standards 2Health News:Two-step decision tree analysis helps inform updates of RT best practices, quality standards 3
... Dental Service Building for Early Childhood Oral Health at ... to provide 30,000 patient visits annually, SEATTLE, Nov. ... and Children,s Hospital and Regional Medical Center,today announced they ... dental disease with the development of a new pediatric ...
... and Reject ... Ramius, Opposition Slate, MONTVALE, ... mailed the following letter to all shareholders from,Lawrence Saper, Chairman ... Company,s Annual Meeting of Shareholders scheduled for,Thursday, December 20, 2007. ...
... Wash., Nov. 16 CellCyte Genetics,Corporation (the ... Tony,Colasin as its Director of Business Development ... licensing efforts. Tony Colasin was former ... From January 2001 to January 2007, he ...
... gave up as he,battled corporate investors as they took over ... him about greed and ethics,"isn,t the kind of thing you ... education to good use, pulling together an,experienced management team this ... juice drink for school-aged children. As co-founder and CEO ...
... Neutrogena(R), a worldwide leader,in the development of highly ... Diane Lane has signed on to be,an ambassador ... captivating and inspiring actress who personifies the,Neutrogena(R) brand ... her new,role, she will be featured in national ...
... rate between 0 and 2.6% (average 0.3%) in general population. ... tolerated by patients, causing a delay in medical consultation. Together ... with diagnosis and treatment of tinea of the nails. , ... the nails was observed in the Hospital del Mar Pediatric ...
Cached Medicine News:Health News:$5 M Gift Boosts Childhood Oral Health Care Offered by UW, Children's Hospital 2Health News:Datascope Mails Letter to Shareholders 2Health News:Datascope Mails Letter to Shareholders 3Health News:Datascope Mails Letter to Shareholders 4Health News:Datascope Mails Letter to Shareholders 5Health News:Datascope Mails Letter to Shareholders 6Health News:Datascope Mails Letter to Shareholders 7Health News:Datascope Mails Letter to Shareholders 8Health News:CellCyte Genetics Corp. Appoints Tony Colasin as Director of Business Development 2Health News:CellCyte Genetics Corp. Appoints Tony Colasin as Director of Business Development 3Health News:CellCyte Genetics Corp. Appoints Tony Colasin as Director of Business Development 4Health News:Fruit 66 Creator Takes the High Road to Create a Healthy Drink for Students 2Health News:Oscar-Nominated Actress Signs on as Neutrogena(R) Brand Ambassador 2Health News:Tinea of the nails underdiagnosed in children 2
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Endoscopes are also available in fully autoclavable models in 1.8, 2.7, 4.0. 5.0 and 10.0 mm diameters. Manufactured with precise swiss lenses. Built-in temperature measuring device to exactly determ...
Kleinert-Kutz Single Skin Hook, Large...
Medicine Products: