Navigation Links
Significant potential of late- and mid-stage Novartis hematology portfolio to be showcased at upcoming ASH meeting
Date:12/2/2009

s occurred in patients with multiple comorbidities and who were in advanced stages of their hematologic disorders. There have also been reports of renal tubulopathy in patients treated with EXJADE. Give particular attention to monitoring serum creatinine in patients who: are at increased risk of complications, have pre-existing renal conditions, are elderly, have comorbid conditions, or are receiving medicinal products that depress renal function.

Assess serum creatinine in duplicate before initiating therapy to establish a reliable pretreatment baseline, due to variations in measurements. Monitor serum creatinine monthly thereafter. In patients with additional renal risk factors (those who are at increased risk of complications, have pre-existing renal conditions, are elderly, have comorbid conditions, or are receiving medicinal products that depress renal function), monitor serum creatinine weekly during the first month after initiation or modification of therapy and monthly thereafter. Nonprogressive increases in serum creatinine have been noted in 38% of EXJADE-treated patients, compared to 14% of deferoxamine-treated patients in Study 1 and 36% vs 22%, respectively in Study 3, and appear to be dose related. These increases were within the normal range in 94% of patients. EXJADE dosages were adjusted when serum creatinine elevations were detected during the study.

Consider dose reduction, interruption, or discontinuation for elevations in serum creatinine. For adult patients, reduce the daily dose of EXJADE by 10 mg/kg if a rise in serum creatinine to >33% above the average of the pretreatment measurements is seen at 2 consecutive visits, and cannot be attributed to other causes. For pediatric patients, reduce the dose by 10 mg/kg if serum creatinine levels rise above the age-appropriate upper limit of normal at 2 consecutive visits. If there is a progressive increase in serum creatinine beyond the age-appropriate upper limit of normal
'/>"/>

SOURCE Novartis
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

Related medicine technology :

1. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
2. DEFLUX(R) Significantly Reduces Urinary Tract Infections in Children With Vesicoureteral Reflux
3. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
4. Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)
5. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
6. Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent
7. Phase III Clinical Trial in Newly Diagnosed Multiple Myeloma Stopped Early Due to Highly Significant Efficacy Advantage of VELCADE(R) (Bortezomib) for Injection Based Therapy Across All Endpoints
8. Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
9. DOV 21,947 Demonstrates Significant Body Weight and BMI Reductions in Drug- Compliant Subjects in Phase Ib Clinical Study
10. FASgen Announces Significant Milestone in Its Cancer Drug Development Program
11. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... 2014 Decision Resources Group finds that, for ... ( France , Germany ... and the United Kingdom ... once-daily long-acting beta2 agonist/inhaled corticosteroid (LABA/ICS) fixed-dose combination (FDC), ... as a first-line LABA/ICS FDC in the treatment of ...
(Date:7/24/2014)... -- "North America Orthopedic Braces and Supports Market Outlook ... America Orthopedic Braces and Supports market. The report provides ... units) and average price data (in US dollars), within ... , Ankle Braces and Supports , Spinal ... Supports. Photo - http://photos.prnewswire.com/prnh/20140723/129806 ...
(Date:7/24/2014)... BOSTON , July 24, 2014 Boston ... on Tomorrow (#PedInno14), will feature an "Innovation Tank" ... innovators an opportunity to pitch their business or product ... of funding and feedback on how to accelerate the ... competition, occurring the morning of Friday, October 31, will ...
Breaking Medicine Technology:Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 2Surveyed EU5 Pulmonologists Expect that Relvar, the First Once-Daily LABA/ICS FDC, Will Experience Healthy Uptake in Asthma 3North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 2North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 3North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 4North America Orthopedic Braces and Supports Market (Knee, Ankle & Spinal Braces) to 2020 5Taking on Tomorrow to Feature "Innovation Tank" Pitch Opportunity for Aspiring Pediatric Health Care Entrepreneurs 2Taking on Tomorrow to Feature "Innovation Tank" Pitch Opportunity for Aspiring Pediatric Health Care Entrepreneurs 3
... /PRNewswire-Asia-FirstCall/ -- China Medical Technologies, Inc. (the "Company") (Nasdaq: ... diagnostic ("IVD") company, announced its unaudited financial results for ... FY2010") today. 3Q FY2010 ... 2009December 31, 2010December 31, ...
... Zimmer Holdings, Inc. (NYSE: ZMH ; SIX: ... launch of the PathFinder NXT™ System at the ... San Diego, CA.  The PathFinder NXT System builds ... PathFinder Minimally Invasive Pedicle Screw System to ...
Cached Medicine Technology:China Medical Technologies Reports Third Fiscal Quarter Financial Results 2China Medical Technologies Reports Third Fiscal Quarter Financial Results 3China Medical Technologies Reports Third Fiscal Quarter Financial Results 4China Medical Technologies Reports Third Fiscal Quarter Financial Results 5China Medical Technologies Reports Third Fiscal Quarter Financial Results 6China Medical Technologies Reports Third Fiscal Quarter Financial Results 7China Medical Technologies Reports Third Fiscal Quarter Financial Results 8China Medical Technologies Reports Third Fiscal Quarter Financial Results 9China Medical Technologies Reports Third Fiscal Quarter Financial Results 10China Medical Technologies Reports Third Fiscal Quarter Financial Results 11China Medical Technologies Reports Third Fiscal Quarter Financial Results 12China Medical Technologies Reports Third Fiscal Quarter Financial Results 13China Medical Technologies Reports Third Fiscal Quarter Financial Results 14China Medical Technologies Reports Third Fiscal Quarter Financial Results 15China Medical Technologies Reports Third Fiscal Quarter Financial Results 16China Medical Technologies Reports Third Fiscal Quarter Financial Results 17China Medical Technologies Reports Third Fiscal Quarter Financial Results 18China Medical Technologies Reports Third Fiscal Quarter Financial Results 19China Medical Technologies Reports Third Fiscal Quarter Financial Results 20China Medical Technologies Reports Third Fiscal Quarter Financial Results 21China Medical Technologies Reports Third Fiscal Quarter Financial Results 22Zimmer Launches PathFinder NXT™ Minimally Invasive Pedicle Screw System 2Zimmer Launches PathFinder NXT™ Minimally Invasive Pedicle Screw System 3
(Date:7/24/2014)... July 25, 2014 The report, ... the CDN market into various sub-segments with an ... identifies the drivers and restraints for this market ... Browse 93 market data tables and 36 figures ... “Content Delivery Networks (CDN) Market” at http://www.marketsandmarkets.com/Market-Reports/content-delivery-networks-cdn-market-657.html ...
(Date:7/24/2014)... HealthDay Reporter THURSDAY, July 24, 2014 (HealthDay ... dead wrong, according to a small study that asked boys what ... boys between the ages of 14 and 16, researchers found that ... closeness and trust. Very few boasted about sexual conquests or saw ... girl. "In our culture, we have lots of assumptions about ...
(Date:7/24/2014)... RI (PRWEB) July 24, 2014 Pools and ... But the water can be dangerous, especially for small children, ... promote water safety. , According to the Centers for Disease ... 4 are most at risk for water-related injuries and deaths. ... children safe around water, so Amica is offering the following ...
(Date:7/24/2014)... (HealthDay News) -- Drinking caffeine may worsen the hot ... women as they go through menopause, new survey data ... suggests that limiting caffeine intake may be useful for ... night sweats," said researcher Dr. Stephanie Faubion, director of ... Rochester, Minn. But caffeine -- a stimulant found ...
(Date:7/24/2014)... Horizon BCBSNJ’s second annual “Back to ... a rent-free week in a beautiful Lavallette shore house, ... miss your chance to win a week’s vacation at ... New Jersey residents, 25 or older.* Residents can enter ... . , “A family vacation at the Jersey ...
Breaking Medicine News(10 mins):Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 2Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 3Health News:CDN Market by Delivery Technologies & Solutions Expected to Reach $12.16 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Teenage Boys Want Intimacy, Not Just Sex, Survey Finds 2Health News:Teenage Boys Want Intimacy, Not Just Sex, Survey Finds 3Health News:Keep Kids Safe in the Water with 5 Tips from Amica 2Health News:Is Coffee Aggravating Your Hot Flashes? 2Health News:(Beach) Sands of Time Running out to Enter Horizon Blue Cross Blue Shield of New Jersey’s 2014 “Back to the Boardwalk” Sweepstakes 2
... in year-end KLAS survey, PITTSBURGH, Jan. 10 ... by major healthcare providers who,use automated patient flow ... The ranking was listed in the KLAS 2007 ... thousands of healthcare professionals of,health information technology vendors ...
... Clients Suffering from Smoking-Related Illnesses Fight Back against Big ... ... trial attorney, Willie,Gary, along with partners, CK Hoffler, Donald Watson and ... Watson and,Sperando, P.L. announced today that the firm will be representing ...
... climate change was a leading topic of interest for ... two stories that portrayed significantly different messages about the ... Stories in 2007 were identified by monitoring Web site ... highest total number of visits between January and December ...
... at The University of Texas Health Science Center at ... human saliva to provide an early, non-invasive diagnosis of ... Jan. 10, 2008 issue of the journal "Cancer Investigation." ... cancer produces a change in the normal type and ...
... care quality evaluator determines programs improve ... ... Health,Solutions, Inc., (NYSE: MHS ) today announced that it has ... member engagement programs that improve pharmacy care and,prescription drug safety. The ...
... discovery company builds strong financial and clinical foundation, in preparation for ... ... for diabetes, EMERYVILLE, Calif., Jan. 10 ... in its drive to,release Tethys Diabetes PreDxTM, a multi-biomarker technology that ...
Cached Medicine News:Health News:KLAS Ranks TeleTracking Bed Management Suite No. 1 2Health News:Famed Attorney Willie Gary Files $10.6 Billion in Lawsuits against Big Tobacco Companies on Behalf of Florida Smokers and their Families 2Health News:Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007 2Health News:Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007 3Health News:Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007 4Health News:Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007 5Health News:Climate change, gender differences, health among EurekAlert! 10 Most Popular Stories in 2007 6Health News:UT Health Science Center researchers decoding saliva to detect breast cancer 2Health News:UT Health Science Center researchers decoding saliva to detect breast cancer 3Health News:Medco's Specialized Pharmacists, Safety Programs Gain Therapy Management Accreditation 2Health News:Medco's Specialized Pharmacists, Safety Programs Gain Therapy Management Accreditation 3Health News:Medco's Specialized Pharmacists, Safety Programs Gain Therapy Management Accreditation 4Health News:Tethys Bioscience Hits Key Milestones With Series C Funding, Opening of CLIA Laboratory 2Health News:Tethys Bioscience Hits Key Milestones With Series C Funding, Opening of CLIA Laboratory 3
Single Use Loading Units with Titanium Staples for use with Powered MULTIFIRE ENDO GIA™ 60 (15 mm Single Use Stapler with Titanium Staples)....
Providing maximum versatility and maneuverability, the Articulator 35 is the only stapler for use in endoscopic and open procures that provides greater access to targeted structures with limited oper...
Improved Access in Open Procedures with Compact Endoscopic Linear Cutters., ,Staplers may be reloaded seven times for a total of eight firings. Different cartridges of the same size can be interchan...
... ETS45 and ETS-FLEX45 Endoscopic Linear ... and cut line. The 34cm ... suitable for many minimally invasive ... intended for transection, resection, and/or ...
Medicine Products: