Navigation Links
Significant potential of late- and mid-stage Novartis hematology portfolio to be showcased at upcoming ASH meeting
Date:12/2/2009

ution or improvement of the bullous reaction.

Clinical cases of hypothyroidism have been reported in thyroidectomy patients undergoing levothyroxine replacement during treatment with Gleevec. TSH levels should be closely monitored in such patients.

Consider potential toxicities--specifically liver, kidney, and cardiac toxicity, and immunosuppression from long-term use.

Fetal harm can occur when administered to a pregnant woman; therefore, women of childbearing potential should be advised to not become pregnant while taking Gleevec tablets and to avoid breast-feeding while taking Gleevec tablets because of the potential for serious adverse reactions in nursing infants. Sexually active female patients taking Gleevec should use adequate contraception. If the patient does become pregnant while taking Gleevec, the patient should be advised of the potential hazard to the fetus.

Gleevec is metabolized by the CYP3A4 isoenzyme and is an inhibitor of CYP3A4, CYP2D6, and CYP2C9. Dosage of Gleevec should increase by at least 50%, and clinical response should be carefully monitored, in patients receiving Gleevec with a potent CYP3A4 inducer such as rifampin or phenytoin. Examples of commonly used drugs that may significantly interact with Gleevec include ketoconazole, acetaminophen, warfarin, erythromycin, and phenytoin. (Please see full Prescribing Information for other potential drug interactions.)

For daily dosing of 800 mg and above, dosing should be accomplished using the 400-mg tablet to reduce exposure to iron.

Common side effects of Gleevec tablets

The majority of adult patients with Ph+ CML who received Gleevec in clinical studies experienced adverse reactions at some time, but most were mild to moderate in severity. The most frequently reported adverse reactions (all Grades) were superficial edema (60%-74%), nausea (50%-73%), diarrhea (43%-57%), musculoskeletal pain (38%-49%), rash an
'/>"/>

SOURCE Novartis
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25

Related medicine technology :

1. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
2. DEFLUX(R) Significantly Reduces Urinary Tract Infections in Children With Vesicoureteral Reflux
3. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
4. Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)
5. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
6. Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent
7. Phase III Clinical Trial in Newly Diagnosed Multiple Myeloma Stopped Early Due to Highly Significant Efficacy Advantage of VELCADE(R) (Bortezomib) for Injection Based Therapy Across All Endpoints
8. Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
9. DOV 21,947 Demonstrates Significant Body Weight and BMI Reductions in Drug- Compliant Subjects in Phase Ib Clinical Study
10. FASgen Announces Significant Milestone in Its Cancer Drug Development Program
11. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... 2014 Kewaunee Scientific Corporation (Nasdaq: ... its quarterly cash dividend by 9% to twelve cents ... beginning with the dividend payable on September 22, 2014 ... on September 8, 2014. About Kewaunee ... Scientific Corporation is a recognized global leader in the ...
(Date:8/27/2014)... NINGBO, China , Aug. 27, 2014 /PRNewswire/ ... Co., Ltd, ("Menovo") today announced they had entered into ... primarily targeting the United States ... Menovo will jointly develop products for Amerigen to commercialize ... will be responsible for manufacturing API and finished product ...
(Date:8/27/2014)... 27, 2014 Ambit Biosciences (Nasdaq: AMBI ), ... targeting unmet needs in oncology, autoimmune and inflammatory disease, today ... Conference to be held at The New York Palace Hotel ... 3-4, 2014. Alan Fuhrman , Ambit,s CFO, ... drug candidate, quizartinib, at 1:10 p.m. ET on Wednesday, September ...
Breaking Medicine Technology:Amerigen Pharmaceuticals Limited and the Ningbo Menovo Pharmaceutical Co., Ltd, today announced they had entered into a collaboration agreement regarding the development of generic pharmaceuticals, primarily targeting the United States market 2Ambit Announces Participation At Baird 2014 Health Care Conference 2
(Date:8/28/2014)... New York (PRWEB) August 28, 2014 An ... back and neck issues, Cloud 9 Spine offers their resources ... spine problems can quickly become a brick wall of discouragement ... for a professional opinion, Cloud 9 Spine offers ... proprietary technology merged with human interaction that sets Cloud 9 ...
(Date:8/28/2014)... Alpine, NJ resident Othon Mourkakos is proud to ... Tiaras, to benefit the Immune Deficiency Foundation (IDF) Walk ... in Foley Square, New York. IDF is the ... (PI) are a group of more than 200 rare, ... immune system is missing or functions improperly. In ...
(Date:8/28/2014)... The revenue cycle process touches on ... time a patient books an appointment with a physician’s ... payments for services rendered to the healthcare provider. ... has the RCM process down to a science. Over ... common place in nearly every healthcare facility around the ...
(Date:8/27/2014)... Asheville, NC (PRWEB) August 28, 2014 ... for companies to acquire as part of a ... business. Aeroflow is positioned for taking ownership of ... foundation to increase economies of scale. , Last ... an agreement with Hometown Respiratory to increase service ...
(Date:8/27/2014)... Spine Guide has built a reputation for itself ... health. Now, the e-health site will offer new surgical ... pain symptoms. Spine Guide specializes in three types of ... surgery. , Some of the most common back pain ... radiating down the leg, inability to stand up straight, ...
Breaking Medicine News(10 mins):Health News:Making Waves on the East Coast, Cloud 9 Spine is Helping Patients Find Appointments With Local Spine Doctors 2Health News:Tips on Automating the Revenue Cycle Process with Medical Billing 2Health News:Tips on Automating the Revenue Cycle Process with Medical Billing 3Health News:Aeroflow Healthcare Seeks Strategic Acquisition Opportunities 2Health News:Spine Guide Offering New Overview of Surgical Options For Back Pain 2
... Switzerland and Brussels, Belgium, 9 April 2008: The European ... European CanCer Organisation have united forces to host a ... best and most updated scientific data for everyone working ... providing all cancer patients with equal access to high-quality ...
... 2008 Ever wonder if,your doctor personally follows the ... to the recent "Life ... supplemented" Healthcare,Professionals (HCP) Impact ... behaviors, with three of the top shared healthy behaviors,being: ... regularly (73,percent) and taking vitamins and other supplements (72 ...
... Research, Programs for #1 Cause of,Fatal and Nonfatal Injuries ... A broad-based,coalition of nonprofit organizations dedicated to improving the ... of S. 845, the Safety,of Seniors (SOS) Act, clearing ... point: each year, one in three older Americans (65 ...
... counterintuitive to exercise when suffering with joint pain, but ... most people suffering from arthritis. A recent study ... regular exercise, specifically the Arthritis Foundation Exercise Program, is ... pain. This is good news for the aging ...
... April 8, 2008 The Procter &,Gamble Company (NYSE: ... in the quarterly dividend from thirty-five cents ($0.35) to forty,cents ... Series A and Series,B ESOP Convertible Class A Preferred Stock ... shareholders of record at the close of business on,April 18, ...
... Chinese studies show cancer treatment extended survival time in ... combination of the active ingredients in reishi mushrooms and ... survival time of mice with sarcomas, two Chinese studies ... fat, muscle, blood vessels, or other connective or supportive ...
Cached Medicine News:Health News:European Society for Medical Oncology and European CanCer Organization join forces 2Health News:Doctors' and Nurses' Wellness Checklist: Healthy Diet, Exercise, Dietary Supplements 2Health News:Doctors' and Nurses' Wellness Checklist: Healthy Diet, Exercise, Dietary Supplements 3Health News:Elder Falls Bill Passes Congress, Heads to President 2Health News:Elder Falls Bill Passes Congress, Heads to President 3Health News:Physical activity is natural pain reliever for arthritis 2Health News:Green Tea, Mushroom Extract Combo Slows Sarcomas 2
The High Pure Viral RNA Kit is intended for general laboratory use and is designed to purify viral RNA from serum or plasma. Viral RNA is used for RT-PCR analysis directly after elution in nuclease-f...
... This revolutionary product will provide you ... type of electroretinogram, visual evoked potential, ... ganzfeld will allow you to perform ... on-off, double flash, photopic negative response, ...
The PersonalLAB junior is an automated microplate analyzer capable of fully automating immunoenzymatic techniques using a microplate format, per the reagent manufacturer's instruction for use and spe...
... is designed for high throughput microplate processing. ... S60 Stacker that handles up to 60 ... base model is equipped with a dual ... units may be interfaced to increase flexibility ...
Medicine Products: