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Significant Rise in Survival Rates for Elderly Lung Cancer Patients Treated Using Radiosurgery in Netherlands Detailed at World Conference for Lung Cancer
Date:7/6/2011

who added that it has enabled his clinic to treat large targets with less risk to surrounding healthy tissue.

In a related paper,(3) Dr. Max Dahele from VU suggests that during the typical time taken to deliver lung SBRT with high dose rates, "near-rigid fixation" is not necessary and using a Novalis™ Tx linear accelerator the hospital's standard approach is now to treat without external immobilization.  "A simpler and more comfortable approach to patient set-up and positioning achieves comparable stability to that reported with near-rigid immobilization devices, without the associated cost and complexity," said Dr. Dahele.

Another VU presentation(4) discussed chest wall toxicity in the risk-adapted SBRT fractionation scheme that VU university medical center employs and concluded -- based on a review of 530 tumors -- that severe chest wall pain is uncommon after risk-adapted fixed-beam SBRT, particularly in tumors located 5mm or more from the chest wall. They pointed out that this contrasts with published chronic chest wall toxicity observed in up to 30% of patients undergoing surgery.

In a paper(5) on 177 potentially operable early-stage non-small cell lung cancer patients who elected to undergo SBRT instead of surgery, the VU team concluded that such patients receiving SBRT had a median overall survival rate of more than five years and a local control rate of 93%, an impressive statistic. The three-year overall survival rate was nearly 85%, which compares favorably with results reported in earlier studies.  "These findings are comparable to results found in surgery and support ongoing randomized clinical trials that compare surgery and SBRT in such operable patients," the paper concludes. "Short-term outcomes were superior to surgery and long-term outcomes were equivalent to surgery."

Varian Symposium

The World Conference on Lung Cancer also included a symposium entitled "Expanding Options for High-Risk O
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SOURCE Varian Medical Systems
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