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Signalife Completes Testing of Modules for Holter and Intra-Cardiac Monitor
Date:10/1/2007

LOS ANGELES, Oct. 1 /PRNewswire-FirstCall/ -- Signalife, Inc. (Amex: SGN - News) has announced that is has completed in-house testing and technological evaluation of various new modules for its holter and intra- cardiac monitors - items that have previously been an important part of the Company's business plans and are now ready for submission to FDA for clearance. Applications for FDA approval will now be made imminently in the fourth quarter.

Both of these developments are ahead of schedule, and are of importance because they are both revenue producing as well as scientifically significant to the reduction of the $400 billion in cardiovascular expenses as well as to patient health and welfare. Having them completed ahead of schedule will likely bring these products to the forefront several quarters earlier than anticipated - both from a revenue standpoint as well as a scientific venturing standpoint.

About Signalife

Signalife, Inc. is a life sciences company focused on the monitoring and detection of disease through continuous biomedical signal monitoring. Signalife uses its patented signal technology to design and develop medical devices that simplify and reduce the costs of diagnostic testing and patient monitoring in an ambulatory setting.

Signalife is publicly traded on the American Stock Exchange under the symbol SGN. The website for the company is http://www.Signalife.com. Clear Data. Trusted Results.

Caution Regarding Forward-Looking Statements

Statements in this release that are not strictly historical are "forward- looking" statements. Forward-looking statements involve known and unknown risks, which may cause Signalife's actual results in the future to differ materially from expected results. Factors which could cause or contribute to such differences include, but are not limited to, failure to complete the development and introduction of heart monitoring and other biomedical devices incorporating Signalife's technology, failure to obtain federal or state regulatory approvals governing heart monitoring and other biomedical devices incorporating Signalife's technology, inability to obtain physician, patient or insurance acceptance of for heart monitoring and other biomedical incorporating Signalife's technology, and the unavailability of financing to complete management's plans and objectives, including the development of heart monitoring and other biomedical incorporating Signalife's technology. These risks are qualified in their entirety by cautionary language and risk factors set forth and to be further described in Signalife's filings with the Securities and Exchange Commission.


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