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Signal Genetics and DiagnoCure Announce a US$13.3M Collaboration for the Commercialization of Previstage™ GCC Colorectal Cancer Staging Test
Date:6/29/2011

ence, to determine which patients might benefit most from adjuvant chemotherapy and which could be safely managed without chemotherapy.

To date, results of published studies totaling over 1,000 patients have shown that the GCC biomarker is a better predictor, than traditionally-used factors, of disease recurrence in early-stage colorectal cancer patients.

In particular, in a recent study (Annals of Surgical Oncology, May 2011), in a sub-set of 181 stage II colon cancer patients, the Previstage™ GCC test classified one-third of patients as having a high risk of recurrence following surgery and two-thirds of patients at low risk of recurrence. The high risk group had a six times greater likelihood of recurrence than the low risk group (27% versus 4%).

About Signal Genetics

Signal Genetics, the parent company of Myeloma Health LLC, Respira Health LLC and CC Health LLC, is a privately held predictive genetic testing company focused on improving the treatment of cancer patients. The goal of Signal Genetics is to provide cancer patients and their physicians with novel and innovative insights into their disease, including predictive outcome of disease stage, odds of relapse, and the optimal treatment regimen based on their specific genetic expression profile. The Company launched its first molecular diagnostic test in December, 2010, Myeloma Prognostic Risk Signature (MyPRS™) via its CLIA laboratory in Little Rock, Arkansas. Signal Genetics has marketing partnerships with two large, national laboratories, including Caris Life Sciences and NeoGenomics Laboratories.  Additional information is available at www.signalgenetics.com.

About DiagnoCure

DiagnoCure (TSX: CUR) is a life sciences company that develops and commercializes high-value cancer diagnostic tests that increase clinician and patient confidence in making critical treatment decisions. In 2008, th
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