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Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting
Date:5/17/2013

ts aged 13 to 17: decreased appetite, insomnia, and decreased weight;
  • Adults: decreased appetite, insomnia, dry mouth, diarrhea, nausea, anxiety and anorexia.

  • Please click here for Full Prescribing Information  for Vyvanse, including Boxed WARNING regarding Potential for Abuse and Dependence.

    ABOUT INTUNIV (guanfacine)

    Once-daily INTUNIV is available in four doses-1 mg, 2 mg, 3 mg, and 4 mg. The active ingredient in INTUNIV is guanfacine. INTUNIV is not a central nervous system (CNS) stimulant or a controlled substance, and has no known potential for abuse or dependence. INTUNIV is a selective alpha-2A agonist. The mechanism of action of guanfacine in ADHD is not known.

    INDICATION

    • INTUNIV is indicated for the treatment of ADHD as monotherapy and as adjunctive therapy to stimulant medications in children and adolescents ages 6 to 17. The effectiveness of INTUNIV for more than 8 weeks has not been systematically evaluated. The physician electing to use INTUNIV for extended periods should periodically reevaluate its long-term usefulness for the individual patient.

    IMPORTANT SAFETY INFORMATION

    • Patients with a history of hypersensitivity to INTUNIV, its inactive ingredients, or other products containing guanfacine should not take INTUNIV.
    • Hypotension, bradycardia, and syncope were observed in clinical trials. Decreases in blood pressure and heart rate were dose-dependent and were less pronounced over time of treatment.  Heart rate and blood pressure should be measured prior to initiation of therapy, following dose increases, and periodically while on therapy. Use INTUNIV with caution in patients with a history of hypotension, heart block, bradycardia, car
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    SOURCE Shire plc
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