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Shire Second Quarter Product Sales Up 16%
Date:8/1/2012

other expense, net (10.8) - - - - - (10.8) Income before income taxes and equity in losses of equity method investees 291.4 78.0 7.1 (3.6) 35.9 - 408.8 Income taxes (53.0) (14.5) (2.4) - (13.0) - (82.9) Equity in losses of equity method investees, net of tax (0.6) - - - - - (0.6) Net income 237.8 63.5 4.7 (3.6) 22.9 - 325.3 Impact of convertible debt, net of tax 7.8 - - - - - 7.8 Numerator for diluted EPS 245.6 63.5 4.7 (3.6) 22.9 - 333.1 Weighted average number of shares (millions) - diluted 594.9 - - - - - 594.9 Diluted earnings per ADS 123.9c 32.1c 2.4c (1.8c) 11.4c - 168.0c

The following items are included in Adjustments:

(a) Amortization and asset impairments: Impairment of certain IPR&D intangible assets
    ($27.0 million), amortization of intangible assets relating to intellectual property
    rights acquired ($51.0 million), and tax effect of adjustments;

(b) Acquisition and integration activities: Costs associated with the acquisition of
    FerroKin and the integration of ABH ($5.0 million), charges related to the change in
    fair value of deferred contingent consideration ($2.1 million), and tax effect of
    adjustments;

(c) Divestments, reorganizations and discontinued operations: Re-measurement of DAYTRANA
    contingent consideration to fair value ($3.6 million);

(d) Legal and litigation costs: Costs related to the settlement of litigation and
    external legal costs ($35.9 million), and tax effect of adjustments; and

(e) Depreciation reclassification: Depreciation of $27.9 million included in Cost of
    product sales, R&D costs and SG&A costs for US GAAP separately disclosed for the
    presentation of Non GAAP earnings.


Unaudited results for the
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SOURCE Shire plc
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