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Shire Second Quarter Product Sales Up 16%
Date:8/1/2012

s Millions Millions Basic 557.0 552.3 555.2 551.1 Diluted 594.9 595.1 594.8 594.8

Unaudited US GAAP results for the three months and six months to June 30, 2012
Consolidated Statements of Cash Flows

3 months to June 30, 6 months to June 30, 2012 2011 2012 2011 $M $M $M $M CASH FLOWS FROM OPERATING ACTIVITIES: Net income 237.8 205.5 476.2 416.8 Adjustments to reconcile net income to net cash provided by operating activities: Depreciation and amortization 79.4 68.8 152.4 132.3 Share based compensation 21.5 19.2 43.4 34.9 Impairment of intangible assets 27.0 - 27.0 - Other (0.9) 3.3 (6.5) (2.2) Movement in deferred taxes (3.3) (24.5) (24.1) 17.7 Equity in losses/(earnings) of equity method investees 0.6 (1.2) (0.3) (2.4) Changes in operating assets and liabilities: Decrease/(increase) in accounts receivable 87.6 18.6 22.4 (56.2) (Decrease)/increase in sales deduction accrual (26.9) 34.9 27.6 66.1 Increase in inventory (42.0) (17.9) (67.0) (30.6) Decrease/(increase) in prepayments and other assets 15.0 (18.8) 32.1 (13.8) Increase/(decrease) in accounts payable and other liabilities 65.1 (4.3) 34.7 (77.1) Returns on investment from joint venture 4.9 - 4.9 - Net cash provided by operating activities(A) 465.8 283.6 722.8 485.5 CASH FLOWS FROM INVESTING ACTIVITIES: Movements in restricted cash 0.5 8.9 6.2 4.8 Purchases of subsidiary undertakings and businesses, net of cash acquired (97.0) (719.7) (97.0) (719.7) Purchases of non-current investments (0.6) (2.0) (4.7) (4.5) Purchases of PP&E (32.7) (48.5) (64.4) (95.0) Purchases of intangible assets (21.5) - (43.5) - Proceeds from disposal of non-current investments and PP&E 0.8 - 4.6 - Proceeds from capital expenditure grants - - 8.4 - Proceeds received on sale of product rights 4.8 6.8 10.4 6.9 Returns of equity investments and proceeds from short term investments - 0.5 0.1 1.6 Net cash used in investing activities(B) (145.7) (754.0) (179.9) (805.9)

Unaudited U
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SOURCE Shire plc
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