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Shire Delivers Record Quarterly Revenues and Non GAAP Diluted Earnings per ADS up 42%
Date:7/18/2014

revenues (Q2 2013: 96%).

Year on year growth Non GAAP Product sales(1) Sales $M Sales CER(2) VYVANSE(3) 359.5 +20% +20% ELAPRASE(R) 152.1 +2% +2% LIALDA(R)/MEZAVANT(R) 143.6 +4% +5% REPLAGAL 130.5 +14% +14% CINRYZE 129.9 n/a n/a INTUNIV(R) 100.0 +11% +11% ADDERALL XR(R) 99.8 -11% -11% VPRIV(R) 89.7 +9% +8% FIRAZYR 89.0 +80% +79% PENTASA(R) 63.2 -14% -14% OTHER 112.3 +14% +10% Total 1,469.6 +22% +21%

  1. Product sales from continuing operations, including ViroPharma Inc. acquired January 24, 2014, and excluding DERMAGRAFT which has been treated as discontinued operations following divestment on January 17, 2014.
  2. On a Constant Exchange Rate ("CER") basis, which is a Non GAAP measure.
  3. Lisdexamfetamine dimesylate ("LDX") currently marketed as VYVANSE in the US & Canada, VENVANSE® in Latin America and ELVANSE® in certain territories in the EU for the treatment of ADHD.

VYVANSE - ADHD 

VYVANSE product sales grew strongly in Q2 2014 (up 20% compared to Q2 2013) due to price increases taken since Q2 2013 and to a lesser extent higher prescription demand and good growth in international sales.

ELAPRASE - Hunter syndrome 

ELAPRASE product sales in Q2 2014 were up 2% compared to Q2 2013 driven by continued growth in the number of treated patients, especially in emerging markets. Growth in Q2 2014 was held back due to the timing of shipments to certain markets which order less frequently, which benefited sales in Q2 2013.

LIALDA/MEZAVANT - Ulcerative Colitis 

Product sales for LIALDA/MEZAVANT in Q2 2014 were up 4%, primarily due to higher US prescription demand (estimated to be up 27%), as LIALDA reached a US exit market share of approximately 31% at Q2 2014. Product sales grew at a lower rate than the strong US prescription demand as a result of higher sales deductions as a percentage of product sales and destocking in Q2
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SOURCE Shire plc
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3. Shire Extends Tender Offer for ViroPharma
4. Shire Reports Top-Line Results on OPUS-2, a Phase 3 Study Investigating the Use of Lifitegrast (5.0% Ophthalmic Solution) in Adults With Dry Eye Disease
5. MinuteClinic Opens First Clinic Locations in New Hampshire
6. Block & Leviton LLP Investigates ViroPharma Inc. for Possible Breaches of Fiduciary Duty in Connection with Its Acquisition by Shire PLC.
7. Shire to Present at the Bank of America Merrill Lynch Global Health Care Conference
8. Shire to Present at the Morgan Stanley Global Healthcare Conference
9. Shire Reports 7% Product Sales Growth: Anticipating Double Digit Non GAAP Earnings Growth in 2013
10. Shire Announces Award Recipients for 2013 US ADHD Scholarship Program
11. Shire to Present Scientific Data Across a Range of Psychiatric Disorders at American Psychiatric Association Annual Meeting
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