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Shire Continues to Deliver Excellent Growth From Core Products
Date:10/30/2009

.9 million and $26.0 million have been reclassified from Research and development to Selling, general and administrative costs for the three and nine months to September 30, 2008 respectively. Unaudited US GAAP results for the three months and nine months to September 30, 2009 Consolidated Statements of Operations (continued) 3 months to 3 months to 9 months to 9 months to September September September September 30, 2009 30, 2008 30, 2009 30, 2008 Earnings/(loss) per ordinary share - basic Earnings/(loss) from continuing operations 11.0c (6.3c) 61.1c 2.9c Loss from discontinued operations - (0.2c) (2.3c) (0.2c) Earnings/(loss) per ordinary share - basic 11.0c (6.5c) 58.8c 2.7c Earnings/(loss) per ADS - basic 33.0c (19.5c) 176.4c 8.1c Earnings/(loss) per ordinary share - diluted Earnings/(loss) from continuing operations 10.9c (6.3c) 60.3c 2.9c Loss from discontinued operations - (0.2c) (2.3c) (0.2c) Earnings/(loss) per ordinary share - diluted 10.9c (6.5c) 58.0c 2.7c Earnings/(loss) per ADS - diluted 32.7c (19.5c) 174.0c 8.1c Weighted average number of shares (millions): Basic 540.6 540.3 540.0 542.6 Diluted 548.3 540.3 547.1 545.3 Unaudited US GAAP results for the three months and nine months to September 30, 2009 Consolidated Statements of Cash Flows 3 months 3 months 9 months 9 months
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4. Shires Investigational Nonstimulant ADHD Treatment INTUNIV(TM) (Guanfacine Extended Release) Demonstrated Significant Efficacy in Reducing ADHD Symptoms at All Measured Time Points Up to 24 Hours Postdose
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10. Shire has Filed a Treatment Protocol for Velaglucerase Alfa for Gaucher Disease
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