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Shionogi Inc. Announces FDA Approval of CUVPOSA™ for the Treatment of Chronic Severe Drooling in Pediatric Patients With Neurologic Conditions
Date:7/29/2010

e dosage forms of digoxin.
  • Amantadine:  Effects of glycopyrrolate may be increased with concomitant administration of amantadine.  Healthcare providers should consider decreasing the dose of glycopyrrolate during concomitant use.
  • Atenolol or metformin:  Glycopyrrolate may increase serum levels of atenolol or metformin.  Healthcare providers should consider dose reduction when used with glycopyrrolate.
  • Haloperidol or levodopa:  Glycopyrrolate may decrease serum levels of haloperidol or levodopa.  Healthcare providers should consider a dose increase when used with glycopyrrolate.
  • Use in Specific Populations
    • Pediatric use:  The safety and effectiveness of glycopyrrolate has not been established in patients under 3 years of age.
    • Renal impairment:  Use CUVPOSA™ with caution in patients with renal impairment.

  • About Shionogi Inc.

    Shionogi Inc. is a US-based company of Shionogi & Co., Ltd. Headquartered in Osaka, Japan, Shionogi & Co., Ltd. is a major research-driven pharmaceutical company dedicated to placing the highest value on patients. Shionogi's Research and Development currently targets three therapeutic areas: Infectious Diseases, Pain, and Metabolic Syndrome. The Company has provided such innovative medicines as Crestor and Doripenem, which have been successfully delivered to millions of patients. In addition, Shionogi is engaged in new research areas such as allergy and cancer. Contributing to the health of patients around the world through development in these therapeutic areas is Shionogi's primary goal. For more details, please visit

    SOURCE Shionogi Inc.
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