Navigation Links
Shield Therapeutics Completes Recruitment to Pivotal Phase 3 Programme for Treatment of Iron Deficiency
Date:6/23/2013

LONDON, June 24, 2013 /PRNewswire/ --

Shield Therapeutics, the independent specialty mineral medicines pharmaceutical company, today announces that it has completed recruitment of patients into its pivotal Phase 3 programme of ST10 for the treatment of iron-deficient anaemia.  ST10 is a novel form of ferric iron taken orally.

Patients with inflammatory bowel disease and anaemia have been recruited and randomised when oral ferrous products have been ineffective due to intolerance and/or inadequate therapeutic benefit.  The primary endpoint of this pivotal international, multi-centre programme is haemoglobin change after 12 weeks' treatment with ST10 compared to placebo.  Subjects have been included from expert centres in Austria, Germany, Hungary and the UK and either randomised to receive 30mg of ST10 twice a day, or a matched placebo capsule.  Following the randomised treatment period there is an open-label phase that allows all patients to be treated with ST10 for an additional year.  Other iron therapies have not been permitted during the study.  

Shield Therapeutics expects to report top-line results from the study at the end of Q4 2013 and anticipates these results will provide confirmatory pivotal clinical data that may form the basis of an MAA submission to the European regulatory authorities in 2014.  The data is also expected to form part of a subsequent NDA submission in the USA.

Commenting on the study, Professor Gasche, Professor of Medicine, Medical University of Vienna, Austria said:

"Inflammatory bowel disease is one of the most prevalent diseases managed by gastroenterologists.  Approximately half of all IBD patients develop iron deficiency and that can readily progress to more severe anaemia, which is the lead
'/>"/>

SOURCE Shield Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. ASSA ABLOY Door Group Announces RF Shielding Openings
2. Blue Cross Blue Shield Texas Launches "Be Covered Texas" Campaign to Raise Awareness of Individual Health Insurance Enrollment Options
3. Radiation Detection, Monitoring & Safety Market (Geiger Counter, Ionization Chamber, Scintillator, Terahertz detector, Dosimeter, Environment Monitor, Shield, Lead Apron, Eyewear & Glove) - Competitive Analysis & Global Forecasts to 2017
4. Healthcare Fraud Shield Now Offers SIU Services
5. FDA Grants Soligenix Fast Track Designation for OrbeShield(TM) for the Reduction of Mortality Associated with Gastrointestinal Acute Radiation Syndrome (GI ARS)
6. BI-LO Offers Health Giveaways With Flu Vaccinations, Encourages Community To Shield Their Health This Flu Season
7. Shield HealthCare Announces 12th Annual Caregiver Story Contest
8. Wellness Center USA, Inc. Completes Psoria-Shield Inc. Acquisition
9. Healthcare Expense Management Leader Patientco Receives $3.75M in funding led by BlueCross BlueShield Venture Partners and Sandbox Industries
10. Wellness Center USA Inc. Signs Agreement to Acquire Psoria-Shield Inc.
11. Blue Cross Blue Shield of Michigan and Blue Care Network support the Drug Enforcement Administrations Nationwide Prescription "Drug Take-Back Day"
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2014)... YORK , Aug. 28, 2014 ... is available in its catalogue: Germany ... 2020 http://www.reportlinker.com/p02343442/Germany-Aesthetic-Lasers-and-Energy-Devices-Market-Outlook-to-2020.html ... Outlook to 2020 Summary GlobalData,s new ... Outlook to 2020", provides key market data on ...
(Date:8/28/2014)... /PRNewswire-iReach/ -- EDGE Orthopaedics, a new entry in ... announce they have received their second FDA 510(k) ... Fracture Plating System. The VIEW Plating ... indications within the mid-foot. The system includes titanium ... (CC), Talonavicular (TN) and Evans plates along with ...
(Date:8/28/2014)... CITY , Aug. 28, 2014 /PRNewswire-iReach/ -- Academy ... by service academy graduates, has published a case ... three-day Leadership Excellence Course . In September and ... Excellence Course to Albuquerque , Indianapolis ... . Photo - http://photos.prnewswire.com/prnh/20140828/140814 ...
Breaking Medicine Technology:Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 2Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 3Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 4Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 5Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 6Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 7Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 8Germany Aesthetic Lasers and Energy Devices Market Outlook to 2020 9EDGE Orthopaedics Receives Second FDA Clearance 2Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 2Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 3Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 4Academy Leaders Publishes Case Study on Work with Global Pharmaceutical Company 5
... Cancer Journal , AUSTIN, Texas--(BUSINESS WIRE)--May 30, 2007--Introgen,Therapeutics, ... the dramatic clinical benefit of its lead product,Advexin ... of cancer known as,Li-Fraumeni Syndrome (LFS), a genetic ... suppressor gene. This is the,first reported treatment of ...
... CITY, Calif.--(BUSINESS WIRE)--May 29, 2007 - Gilead,Sciences, ... III,AIR-CF1 (CP-AI-007) study of aztreonam lysine for ... fibrosis (CF) who have,pulmonary Pseudomonas aeruginosa (P. ... at Day 28 from baseline in respiratory,symptoms, ...
Cached Medicine Technology:Introgen's Advexin Demonstrates Clinical Benefit in Inherited,Cancer 2Introgen's Advexin Demonstrates Clinical Benefit in Inherited,Cancer 3Introgen's Advexin Demonstrates Clinical Benefit in Inherited,Cancer 4Gilead Announces Achievement of Primary Efficacy Endpoint in Second,Phase III Study of Aztreonam Lysine for Inhalation in Patients With,Cystic Fibrosis 2Gilead Announces Achievement of Primary Efficacy Endpoint in Second,Phase III Study of Aztreonam Lysine for Inhalation in Patients With,Cystic Fibrosis 3Gilead Announces Achievement of Primary Efficacy Endpoint in Second,Phase III Study of Aztreonam Lysine for Inhalation in Patients With,Cystic Fibrosis 4Gilead Announces Achievement of Primary Efficacy Endpoint in Second,Phase III Study of Aztreonam Lysine for Inhalation in Patients With,Cystic Fibrosis 5
(Date:8/29/2014)... neuroregenerative effect, stimulating neurite extension in the ... and enhancing nerve regeneration following nerve crush ... FK506 to stimulate nerve regeneration is limited ... and hypertension, and its considerable cost. With ... other drugs reportedly cause life-threatening infections. Like ...
(Date:8/29/2014)... August 29, 2014 The Fresh Diet, ... introduce its new Fresh Vegetarian meal plan. Originating from ... meals, the new menu is designed to satisfy customers ... lifestyle. , Responding to the growing demand ... a multi-billion dollar market (Forbes) with 14% of Americans ...
(Date:8/29/2014)... 2014 Glendale Botox experts at ... Botox throughout the month of September. This special offer features ... syringes of Juvederm. Patients can take advantage of this special ... Glendale Botox experts will work with patients to determine if ... What is Botox? , Botox is a treatment made ...
(Date:8/29/2014)... FRIDAY, Aug. 29, 2014 (HealthDay News) -- Researchers have ... in their brains. Dyslexia -- the most commonly ... problems with reading and writing. Previous research showed ... but most of those studies focused only on a ... used functional MRI to analyze how multiple brain regions ...
(Date:8/29/2014)... VA (PRWEB) August 29, 2014 For ... Research Foundation (Meso Foundation) will be observing September 26th ... on Rockefeller Plaza, in New York. , Members ... encouraged to RSVP . The Foundation will be providing ... the past years, mesothelioma community members have received attention ...
Breaking Medicine News(10 mins):Health News:The Fresh Diet America's #1 At-Home Meal Delivery Company, Debuts Fresh Vegetarian Meal Plan Offering All-Natural Ingredients 2Health News:The Fresh Diet America's #1 At-Home Meal Delivery Company, Debuts Fresh Vegetarian Meal Plan Offering All-Natural Ingredients 3Health News:Glenoaks Laser Center is Now Offering a Special Promotion on Botox for the Month of September 2Health News:Scientists Find Differences in Brains of Those With Dyslexia 2Health News:Organization to Raise Awareness of Mesothelioma on the Today Show 2
... A night of food and festivities for a great ... ActionAIDS has shown their appreciation for people who through ... a very real difference in the lives of men, ... recognizes those individuals with their highest honor: The ...
... structuring physician payment incentives around existing empirical evidence ... reduce the cost of healthcare, says a commentary ... Circulation: Cardiovascular Quality and Outcomes . ... suffering from mild chest pain due to coronary ...
... 20 Young Innovations, Inc. (Nasdaq: YDNT ) today ... a live and on-demand web cast conference call on Tuesday, April ... broadcast of the call will be available through InterCall at ... live audio broadcast will also be available through the Company,s website, ...
... Eli Lilly and Company (NYSE: LLY ) today ... $0.49 a share on outstanding common stock. This is ... and maintains the annual indicated dividend rate for 2009 of ... shareholders of record at the close of business on May ...
... (Nasdaq: AMGN ) today announced that it plans ... 23, 2009 after the close of the financial markets. The ... investment community at 2 p.m. Pacific Time. Participating in ... chief executive officer, and other members of Amgen,s senior management ...
... 8-ounce glass enhances absorption of rapamycin 3 to 4 times ... boosts the anti-cancer effects of the drug rapamycin, according to ... tumors, for which there is no effective treatment. , ... as a liquid, once a week. After the first week ...
Cached Medicine News:Health News:Subaru of America CMO Tim Mahoney and Restaurateur Stephen Starr to receive ActionAIDS' Friend for Life Award April 30 2Health News:Subaru of America CMO Tim Mahoney and Restaurateur Stephen Starr to receive ActionAIDS' Friend for Life Award April 30 3Health News:Subaru of America CMO Tim Mahoney and Restaurateur Stephen Starr to receive ActionAIDS' Friend for Life Award April 30 4Health News:Health-care reform should start with paying evidence-based financial incentives to doctors 2Health News:Young Innovations, Inc. Provides First Quarter Conference Call Details 2Health News:Amgen Announces Webcast of 2009 First Quarter Financial Results 2Health News:Grapefruit Juice Boosts Anti-Cancer Drug's Effects 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: