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Seven Presentations by Two Independent Research Groups Highlight Advantages of Pressure Cycling Technology (PCT) at Scientific Symposia in Philadelphia, Boston, and New York City
Date:5/21/2008

the use of PCT and PCT-dependent reagents (ProteoSolve-LRS Kit) for the efficient recovery of proteins from lipid-rich adipose (fat) tissue. Adipose tissue plays a key role in several biomedical processes that are linked to obesity, insulin resistance, inflammation, and other physiological complications. Dr. Ivanov indicated that efficient and good quality analysis of adipose tissue is highly valuable in studies of these diseases. Adipose tissue is comprised of up to 80-90% lipid, which makes conventional detergent-based protein extraction methods inefficient and difficult. Dr. Ivanov found that the combination of PCT and ProteoSolve-LRS resulted in a much faster, less expensive, and higher quality extraction process, as compared to current methods.

ACS MID-ATLANTIC REGIONAL MEETING (MARM 2008 - New York, NY). Dr. Pevsner gave an oral presentation on Tuesday May 20th. In addition, he and his colleagues from the NYU School of Medicine and the Brooklyn Hospital Center also gave four poster presentations at this meeting. Dr. Pevsner's talk centered on the importance of sample preparation, and how the quality of sample preparation directly affects the quality of downstream results. Dr. Pevsner shared data illustrating the efficiency and quality of PCT results as compared to conventional methods in use today, and concluded that sample preparation using PCT resulted in a better quality extraction of proteins from tissue samples. On the same day, Dr. Pevsner and his colleagues delivered four poster presentations, which described the use of PCT in the extraction of proteins from breast and colon cancer tissue samples, as well as from the nutrient media used with in-vitro fertilization study procedures. The poster presentations reported that PCT increased protein yield and helped to identify proteins not previously seen in such samples. These presentations concluded that such enhanced extraction of proteins by PCT may result in new therapeutic strategies, diagnostic
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