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Seres Health Completes Enrollment in a Clinical Study for SER-109 in Recurrent Clostridium difficile Infection and Announces Positive Preliminary Data
Date:7/16/2014

h Drug Status from the FDA.  Final complete data and details on the study will be presented at an international conference in the fall of this year.

"The positive results of this trial are very encouraging and support the advancement of SER-109 into late-stage clinical studies for treating recurrent C. difficile, which is currently a real and increasing clinical challenge," said Elizabeth Hohmann, MD, Associate Professor of Medicine, Massachusetts General Hospital, one of the study investigators. "Of particular importance to patients and physicians, the oral capsules are a simple, efficacious alternative to other more invasive procedures."

"There is a critical need to identify an effective, orally delivered community of microbes, as a true drug, to treat this debilitating infection," said Dr. Roger J. Pomerantz, President, CEO and Chairman of Seres Health. "The clinical profile of SER-109 demonstrates the power of Seres' Microbiome TherapeuticsTM discovery platform and gives us high expectations for the advancement of Ecobiotic® candidates in our pipeline for first-line CDI and other serious infections, as well as metabolic disorders and inflammatory conditions."

About SER-109

SER-109 is the lead Seres Health Ecobiotic® microbial therapeutic in clinical testing for the treatment of recurrent Clostridium difficile infection (CDI), an orphan indication. SER-109 was developed utilizing the Seres Health Microbiome Therapeutics™ platform that provides deep insight into the ecologies of disease and then identifies microbial compositions that can catalyze a shift to health. CDI is a rapidly growing problem associated with antibiotic use. Approximately 100,000 - 150,000 of CDI patients in the U.S. have more than one recurrence. Multiple recurrent CDI has recently been designated as an Orphan Drug Indication by the FDA.

About Se
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