Navigation Links
Seahorse XF Technology Helps P&G Research the Science of Skin
Date:9/9/2013

BILLERICA, Mass., Sept. 9, 2013 /PRNewswire/ -- As reported in this week's The Scientist Magazine, Seahorse Bioscience XF Extracellular Flux technology is being utilized by Procter & Gamble (P&G) skin care scientists to pioneer applications in cellular bioenergetics, to discover the right ingredient combinations that could positively impact skin's natural bioenergy production and re-energize aged skin cells.

P&G scientists are the first in the beauty industry to employ the Seahorse XF Analyzer, which simultaneously measures mitochondrial respiration and glycolysis in real-time, to research cellular energetics and measure and evaluate the effect of ingredients on cell metabolism.

"The overall aging that we experience, a lot of it is driven by cellular energetics," stated John Oblong, Ph.D., a principal scientist at P&G. Mary Johnson, M.S., also a principal scientist at P&G added, "Seahorse's analyzer has replaced tedious experiments in which researchers had to isolate individual mitochondria or use special electrodes to measure oxygen consumption. The ease of the Seahorse system has ignited an explosion of studies into cellular bioenergetics in the past decade."

The XF Analyzer measures the two major energy pathways of the cell - mitochondrial respiration and glycolysis - in real-time. By profiling the metabolic activity of skin cells, scientists can
now track and measure cellular energy metrics, such as ATP turnover and NADPH levels, to study the impact of free radical stress mimicking UV exposure in young cells compared to old cells.

"It's exciting to see XF technology being used for this type of novel research," stated David Ferrick, Ph.D., Seahorse Bioscience CSO. "Using the XF Analyzer P&G scientists were able to test and determine which compounds promoted respiration and glycolysis, potentially causing the cells to increase their metabolism and possibly making the skin cells healthier and more attractive."

P&G scientists demonstrated that in vitro skin cells under oxidative stress conditions experience a significant decrease in ATP, which leads to reduced cellular activity. Older cells, in particular, showed a heightened sensitivity to oxidative stress response, suggesting that aging and environmental factors negatively impact cells' ability to produce and consume energy.

About Seahorse Bioscience

Providing industry-leading analytical instruments and assay kits for research and drug discovery. Scientists worldwide are advancing their research in understanding the role of mitochondrial function in cancer, neuroscience, immunology, obesity, diabetes, ageing, cardiovascular function, and safety toxicity. Learn more: www.seahorsebio.com

CONTACT: Naomi Goumillout, 978-671-1619, ngoumillout@seahorsebio.com


'/>"/>
SOURCE Seahorse Bioscience
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Seahorse Bioscience Announces Asia Mito 2012 Travel Award Winners Advancing Cell Metabolism Research
2. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
3. Fujitsu to Showcase Radiation-Hardened RFID Using FRAM Technology at Interphex 2012 in New York City, Booth #2430
4. SolutionStart Corp. Announces John Karagiannis as Vice President of Technology
5. Ultra Clean to Present at the Jefferies 2012 Global Technology, Media & Telcom Conference
6. Amarantus BioSciences to Present at the New York Biotechnology Association (NYBA) 21st Annual Meeting on May 2nd, 2012
7. Johnson & Johnson (China) Investment Ltd. Acquires Guangzhou Bioseal Biotechnology Co., Ltd.
8. DURECT Announces Issuance of U.S. Patents Covering ORADUR® Technology
9. Remedy Informatics Named "Cool Vendor" in Life Sciences by Leading Technology Analyst Firm
10. Pharmaceutics International, Inc. (Pii) Supports University Pharmaceutical Technology Education and Research
11. Physician-Patient Alliance for Health & Safety: Monitoring Technology for PCA Pumps Can Prevent Adverse Events: So Why Are Hospitals Not Using It?
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/25/2016)... and GERMANTOWN, Maryland , May ... QGEN ; Frankfurt Prime Standard: QIA) today announced that ... with Therawis Diagnostics GmbH to develop and commercialize predictive assays ... market PITX2 as a marker to predict effectiveness of anthracycline ... "We are pleased to partner with Therawis, which ...
(Date:5/25/2016)... As illustrated by the Spring ... the numbers and momentum of cannabis in the US ... billions, more research and development push the sector forward. ... Legal Marijuana Markets Report  from from ArcView Market Research ... the increase in sector is attributed to adult use ...
(Date:5/25/2016)... , May 25, 2016 ... the precision of circulating tumour DNA (ctDNA) analysis ... the appointment of Professor Clive Morris ... leadership across the clinical development programme, scientific collaborations, ... help deliver significant improvements in clinical outcomes for ...
Breaking Medicine Technology:
(Date:5/29/2016)... ... May 29, 2016 , ... Whole Health Supply is happy ... that has been available via Amazon.com. This new style of nail clipper has a ... jaw opening is approximately 4mm and the actual handle is 2.5mm thick to accommodate ...
(Date:5/29/2016)... ... 2016 , ... "With 30 unique self-animating web themed intros and complete control ... project," said Christina Austin - CEO of Pixel Film Studios. , ProIntro Web ... in Final Cut Pro X. Pixel Film Studios’ minimalistic titles allow users to add ...
(Date:5/28/2016)... ... May 28, 2016 , ... "Color Grading media can ... drop a preset onto their media," said Christina Austin - CEO of Pixel Film ... can quickly and easily add stylish color grades to their footage. A LUT is ...
(Date:5/28/2016)... ... ... year and a half of planning the Multiple Pathways of Recovery Conference , CCAR ... Conference was held May 2 -4, 2016 at the Mystic Marriott Hotel & Spa ... the many pathways individuals use to get into and sustain their recovery. Pathways of ...
(Date:5/27/2016)... ... May 27, 2016 , ... More than a third of ... not surprising that bariatric surgery has received increased attention in recent years, as an ... when it comes to weight loss, most people are familiar with the basic requirements ...
Breaking Medicine News(10 mins):