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Seahorse Bioscience Announces the XF96 Extracellular Flux Analyzer for Cellular Bioenergetics
Date:10/6/2008

ensions for the greater part of my career and I trust Seahorse's XF technology, which allows us to make multiple simultaneous measurements of oxygen consumption and acid production using cells growing on culture plates," he said. "The XF format allows us to analyze the bioenergetics of cells under normal growth conditions with high throughput, greatly expanding our ability to investigate cellular bioenergetics."

"Seahorse provides a physiologically relevant assay for detecting the effect of RNAi knockdown of mitochondrial genes on cellular bioenergetics," added Vamsi Mootha, from the Broad Institute, MIT and Harvard's Massachusetts General Hospital. "This technology may accelerate the discovery of drugs for mitochondrial diseases."

The XF96 extracellular flux analyzer was developed to provide higher throughput analysis for customers desiring to study mitochondrial function and dysfunction, obesity, diabetes, cancer, ageing disorders, cardiac disease and drug toxicity.

"The first published Seahorse data was reported in a 2006 Nature article. We have been impressed with the breadth and number of new discoveries by the early users of our technology. In only two years, since the introduction of the first XF24 instrument, XF technology has become the new standard for measuring oxygen consumption and glycolysis by cells, replacing the 50 year old Clark Electrode," notes Jay Teich, CEO, Seahorse Bioscience. "And we are confident the XF96 will have a greater impact."

The new XF96 measures the two primary metabolic pathways in cells in minutes, using a label-free, non-destructive method. The easy to use instrument takes little lab space, does not disrupt stand cell culture procedures and provides measurement c.v.'s under 5%, approximately four times better than has been achievable using older technologies.

About Seahorse Bioscience, Inc. Seahorse XF instruments have become the new standard in cellular bioenergetic measurements. Over 200 plu
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SOURCE Seahorse Bioscience, Inc.
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