Navigation Links
Seahorse Bioscience Announces the XF96 Extracellular Flux Analyzer for Cellular Bioenergetics
Date:10/6/2008

Novel technology opens the door to the understanding of and possible

treatments for obesity, diabetes, ageing and cancer

BILLERICA, Mass., Oct. 6 /PRNewswire/ -- Seahorse Bioscience today announced the release of the first ever analytical instrument for the kinetic measurement of mitochondrial oxygen consumption and cytoplasmic glycolysis in cells in a 96 well microplate. For the past 75 years tools for measuring cellular bioenergetics have been relatively unchanged since Warburg designed the Warburg Apparatus in 1932 and Leland Clark invented the Clark oxygen electrode in 1959.

"Without oxygen consumption measurements, the study of cellular bioenergetics would be in the dark ages," said David Nicholls, a leading bioenergetic researcher from Lund University, Sweden and the Buck Institute, Novato, CA. "Respiratory measurements allow us to quantify subtle changes in ATP turnover, mitochondrial uncoupling or respiratory chain inhibition that can immediately identify an interaction of a compound with the cell's energy generation pathways. Prior to the Seahorse, such studies were restricted to laborious single oxygen consumption measurements using the Clark electrode, invented in 1959, that required large amounts of material and was unsuitable for attached cells. The Seahorse requires just 2% of the material previously needed and has 100-fold the throughput! The ability to analyze cell (and therefore mitochondrial) respiration in a 96 well format and at the same time measure glycolytic flux will result in an immediate surge of scientific discoveries and new drugs. In particular it can lead to an early warning if a potential drug interacts with the cell's bioenergetic pathways."

Martin Brand, a leading mitochondrial researcher from the Buck Institute, Novato, CA and the MRC Dunn Human Nutrition Unit, Cambridge, UK comments, "I have been performing individual measurements of oxygen consumption and lactate production using cell susp
'/>"/>

SOURCE Seahorse Bioscience, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. ImmuneRegen BioSciences Reports Material Transfer Agreement with VaxGen, Inc.
2. ImmuneRegen BioSciences, Inc. Demonstrates Radilex(TM) Increases Disease-Fighting White Blood Cells
3. Upstream Biosciences Acquires Innovative Platform Technology and Drug Candidates for Tropical Parasitic Diseases
4. Ardea Biosciences, Inc. Announces Completion of Phase 1 Clinical Trials of Novel Investigational HIV Drug RDEA806
5. Ardea Biosciences, Inc. Presents Results of Phase 1 Studies of RDEA806, a Novel NNRTI for HIV, at 47th ICAAC
6. Ardea Biosciences Lead MEK Inhibitor, RDEA119, to Enter Human Clinical Trials in Advanced Cancer Patients
7. Alacrity Biosciences Announces Positive Results from a Phase 2 Study of Its Dry Eye Treatment ALTY-0501
8. Sangamo BioSciences and Sigma-Aldrich Announce Nature Biotechnology Study Demonstrating Zinc Finger Technology for Modification of Human Stem Cells
9. Regado Biosciences Initiates Phase IIa Clinical Study of REG1 Anticoagulation System
10. Regado Biosciences Presents Positive Data From REG1 Anticoagulation System Phase Ic Study at American Heart Association 2007 Scientific Sessions
11. Regado Biosciences Presents Early Stage Clinical Data for REG1 Anticoagulation System at American Heart Association 2007 Scientific Sessions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... FRANKLIN, Ohio , Jan. 15, 2014  A novel wearable ... it easy and painless for patients to self-inject prescription drugs ... of disorders, including cancer, blood diseases, autoimmune deficiencies, and genetic ... expected to grow to $220B by 2018, according to analysts.   ...
(Date:1/14/2014)... 2014  Luminex Corporation (Nasdaq: LMNX ) today announced ... of 2013 on Monday, February 3, 2014. A press release ... of trading. (Logo: http://photos.prnewswire.com/prnh/20100104/LUMINEXLOGO ) ... operating highlights and financial results for the fourth quarter and ...
(Date:1/14/2014)... , Jan. 14, 2014 The Brandeis Medical Center, led ... a premier and affordable laser tattoo removal experience with ... Brandeis, focus is in providing high quality cosmetic services with cutting ... " Southern California has seen a ...
Breaking Medicine Technology:Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 2Luminex Corporation Fourth Quarter Earnings Release Scheduled for February 3, 2014 3Beverly Hills Physician Features Tattoo Removal with the Astanza Duality Laser, Offers $99 Special 2
... 29, 2011 ViewRay™, Inc., a privately held ... MRI-guided radiotherapy at the annual meeting of the ... – 4 in Miami Beach, Florida, with software ... radiation therapy system is being developed to feature ...
... 29, 2011 Medical Alarm Concepts Holding, Inc. (OTCQB: ... for capital that will be used to accelerate corporate ... first fully-monitored medical alarm system that allows users to ... third of this private investment group funding has already ...
Cached Medicine Technology:ViewRay Demonstrates Potential Therapy Applications for MRI-Guided Radiation at ASTRO 2011 2Medical Alarm Concepts Receives Growth Capital Injection and Commitment for Future Funding 2Medical Alarm Concepts Receives Growth Capital Injection and Commitment for Future Funding 3
(Date:4/23/2014)... Physical Activity on Mobility Limitation in Old Age , ... of mobility limitation in old age, whereas leisure-time physical ... study which followed up 5,200 public sector employees for ... Research Center in Finland and the Finnish Institute of ... wears the body and lasts for several hours a ...
(Date:4/23/2014)... Previous studies have shown that proliferation of endogenous ... damage to neurons and axons. From the perspective ... from Sun Yat-sen University in China observed the ... neural precursor cell proliferation and expression of basic ... the rat brain on the infarct side. The ...
(Date:4/22/2014)... industry leaders visited the New Jersey Institute of ... S. Bloom for the launch of the New ... provides a new model for business innovation through ... assets and investment. U.S. Senator Cory Booker, Panasonic ... Taylor, New Jersey Lieutenant Governor Kim Guadagno, New ...
(Date:4/22/2014)... that can provide primary care for low-income patients ... and insurance companies while improving patient health, researchers ... suggests that health clinics that avoid costs associated ... by lowering hospital admission rates and emergency room ... Penn State Altoona. , The researchers estimated ...
(Date:4/22/2014)... risk of pregnancy among women using a newer method ... 10 times greater over a 10-year period than using ... researchers at Yale University and UC Davis has found. ... Contraception , the study found the higher risk ... the brand name Essure. , "This study provides ...
Breaking Medicine News(10 mins):Health News:Midlife occupational and leisure-time physical activity limits mobility in old age 2Health News:Government and industry leaders herald launch of NJIT's New Jersey Innovation Institute 2Health News:Clinics not bogged down by red tape can ease health cost burdens 2Health News:Risk of pregnancy greater with newer method of female sterilization 2Health News:Risk of pregnancy greater with newer method of female sterilization 3
... Laparoscopic cholecystectomy (LC) has rapidly substituted traditional cholecystectomy, ... of cholelithiasis. ,Bile duct injury (BDI) remains the ... recent survey, published in the October issue of ... BDI has become more frequent with LC. ...
... one of the most neurotoxic plants in western Mediterranean ... are known to be neurotoxic.// This shrub produces a ... the berries. ,Ingestion of few fruits similar ... seizures, coma and apnea. ,A recent paper ...
... issue of the Academy of General Dentistry's monthly newsmagazine, ... and is the most important factor in the prevention ... of the population. ,"Flossing every 24 hours to ... said Gordon Isbell, DMD, MAGD, spokesperson for the Academy ...
... colleagues from Toyama University, Japan have found that supplementation ... children’s behavior. //Researchers have found that Docosahexaenoic acid (DHA), ... an important component of cell membranes of the retina ... boys who have lower concentrations of DHA in blood. ...
... beer and alcohol increases the risk of colorectal tumours, ... to a study. // ,The study, conducted by ... University, Stony Brook, New York, was meant to examine ... of significant colorectal neoplasia in a screening population., ...
... products that would help women protect themselves from sexually ... any form that is convenient to use such as ... microbicides will enable women to negotiate condom use or ... would also help avoid unwanted pregnancies, according to experts.,With ...
Cached Medicine News:Health News:Higher incidence of bile duct injury during laparoscopic cholecystectomy 2Health News:Poisoning by fruits similar to blackberries 2Health News:Alcohol Drinking Affects Risk Of Colorectal Tumours 2
... components that comprise the SmartPill GI ... comprise the SmartPill GI Monitoring System: ... Receiver software and SmartPill MotiliGI software. ... indispensable parts of the SmartPill GI ...
... for POLYGRAM NET™ (PNET) works with ... record and analyze pressure, swallow, and ... procedures. The PNET software and Polygraf ... water-perfused manometry catheters and the RespSponse™ ...
... Advanced pH Analysis for POLYGRAM NET™ ... Testing Application. Like the standard application, Advanced ... by either the Digitrapper™ Catheter-Based pH Recorder ... ,Designed primarily for use by clinical ...
Capillaries available in glass and "non-PVC" plastic. Match different analyzer requirements. Variety of sizes match sample-volume requirements of individual analyzers....
Medicine Products: