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Scripps Research Institute's Richard A. Lerner Wins Prince of Asturias Award for Scientific and Technical Research
Date:5/31/2012

ards will be presented in the autumn in Oviedo at a grand ceremony chaired by H.R.H. the Prince of Asturias. For more information on the awards, see the foundation website at http://www.fpa.es/en/ .

Richard A. Lerner
Richard Alan Lerner (Chicago, USA, 1938) studied medicine at Northwestern University and Stanford, earning his MD at the latter in 1964. Following internship at the Palo Alto Stanford Hospital in 1965, he began his career in research and teaching in the Department of Experimental Pathology at The Scripps Research Institute in La Jolla (California), an institution that he led from 1986 to 2012. He is currently the Lita Annenberg Hazen Professor of Immunochemistry in the Department of Molecular Biology and a member of the Skaggs Institute for Chemical Biology at Scripps Research.

Lerner was the architect of the most important advance since the discovery of monoclonal antibodies a quarter century ago: the conception, design and creation of combinatorial antibody libraries, currently the most widely used of all libraries in the field of biochemistry and which enabled a broadening of the scope of action of the immune system. Lerner set the stage in an article published in Science in 1989 and all the advances produced in the change in combinatorial libraries derived directly or indirectly from this article. Furthermore, in 1991, Lerner identified the essence of the production of antibodies without immunization and his method has remained the most efficient way to produce fully human antibodies. Moreover, Lerner has been a pioneer in the development of what are known as catalytic antibodies, a strategy to accelerate and catalyse chemical reactions for which traditional methods are not efficient.

Author of more than 400 scientific papers, Lerner holds honorary degrees from seven universities in Europe and America. Among other awards, he has received the Wolf Prize in Chemistry (Israel,
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