Navigation Links
Scotland Continues to Forge Ahead in Stem Cell Research

BOSTON, June 12, 2013 /PRNewswire/ -- Scotland's standing as Europe's largest and most highly regarded stem cell research community has been reaffirmed recently by announcements of funding from the UK Medical Research Council (MRC) and the British Heart Foundation to the MRC Centre for Regenerative Medicine (CRM) based at the Edinburgh BioQuarter. As part of a major $25m boost for UK regenerative medicine, the Edinburgh center will play a key role in the development of new therapies.

This and other recent news exemplify Scotland's strength and depth of expertise in this field. Developments at an academic level describing increased understanding of the mechanism of cellular reprogramming were recently reported by Dr. Keisuke Kaje from the MRC-CRM in Nature, whilst Scottish company Roslin Cells and the MRC-CRM have been actively collaborating on iPS cell line production ensuring a more quality-oriented perspective and generating more commercial opportunities.

Elsewhere, exciting research at Heriot-Watt University has seen the use of 3D printing techniques to produce clusters of viable stem cells that could speed up progress towards creating artificial organs. In the immediate future, Professor Will Shu and his team hope the technique can be used to generate biopsy-like tissue samples for drug testing.

At a clinical level also, Scotland has seen some major developments. ReNeuron has announced the successful conclusion of its Phase 1 stem cell clinical trial (PISCES) using its ReN001 therapy for treatment of stroke. This trial has been conducted at the Southern General Hospital, Greater Glasgow & Clyde, by Professor Keith Muir. The company is currently seeking final regulatory and ethical approvals for a Phase II study—scheduled to begin this summer. In a separate announcement ReNeuron has selected Dundee as the location of choice for another Phase 1 stem cell-based clinical trial, this time focused on critical limb ischemia.

Also underway is a 20-patient Phase 1 clinical trial using limbal cells to repair corneal blindness. This is being led by Professor Bal Dhillon in Edinburgh and is funded jointly by the UK Stem Cell Foundation and Scottish Enterprise in partnership with Scotland's Chief Scientist's Office.

Finally, a significant boost to Scotland's capabilities for supporting clinical trials was received with news that the new GMP Manufacturing Facility within the MRC-CRM, and managed by Roslin Cells along with the Scottish National Blood Transfusion Service (SNBTS), has been awarded a license by the Medicines and Healthcare products Regulatory Authority (MHRA), which permits the manufacture and release of Advanced Therapy Medicinal Products (ATMPs) for use in clinical trials.

"Scotland is once again demonstrating its expertise in academic, translational and clinical applications in stem cells and regenerative medicine" says Dr. Ed Hutchinson, spokesperson for life sciences at Scottish Enterprise. "These advances have been made possible through a collaborative approach whereby Scotland's universities, companies and health boards all actively participate in developments in this exciting area. With a supportive supply chain in place, Scotland can be seen as the place to go to undertake stem cell clinical trials and as a base for the European market."

This week, a Scottish delegation including the MRC Center for Regenerative Medicine, Roslin Cells and Universities of Edinburgh and Glasgow, in addition to stem-cell focused companies such as Biogelx and Sistemic, will attend the International Society for Stem Cell Research (ISSCR) conference in Boston. Further information on Scotland's stem cell industry can be found at the Scottish Development International booth, number 331, at the ISSCR conference or visit

Media Contact:
Rebecca Gehman
Development Counsellors International; 212-725-0707

SOURCE Scottish Development International
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Scotland to produce lifesaving HIV technology
2. Scotland-based Innova Partnerships Ltd. Opens Boston Office
3. Canada-based Radimetrics Announces Expansion to Scotland
4. From Cloning Dolly the Sheep to Curing Blindness, Scotland is on the Forefront of Life Science Discoveries
5. BioElectronics Continues FDA Clearance Campaign to Bring Chronic Pain Sufferers Safe, Effective, Inexpensive, Drug-Free Pain Therapy
6. Record Use of At-the-Market (ATM) Offerings Continues in 2013 with $161 Million Raised by U.S. Life Sciences Companies in First Quarter, Reports Brinson Patrick
7. Harlan Laboratories Continues Global Growth with Major Expansion of North American Facilities
8. Pharmaceutical Companies On Defense As Post-ACA Implementation Continues
9. Mission Pharmacal Company Continues Its Support of March for Babies
10. Groupe Athena, Inc. Releases 3rd Quarter Financials, Continues Strong Revenue And Earnings Growth
11. Despite the Recent Availability of Xtandi, Zytiga Continues to Dominate the Second-Line Metastatic Castrate-Resistant Prostate Cancer Setting, According to Surveyed U.S. Oncologists and Urologists
Post Your Comments:
(Date:10/12/2015)... Oct. 12, 2015  Millions of smokers worldwide have ... shackles of tobacco. An April 2015 study ... London showed electronic cigarettes to be up to 95 ... than a decade after the technology was first introduced ... --> --> ...
(Date:10/12/2015)... , Oct. 12, 2015 About epilepsy ... to a spectrum of brain disorders manifested by benign ... by factors ranging from brain malformations and tumors to ... underlying cause of the disease is unidentified, as is ... as idiopathic epilepsy. An imbalance between the inhibitory and ...
(Date:10/12/2015)... , October 12, 2015 --> ... report "Spirometer Market by Product (Hand-held, Table-top, Desktop), Technology (Volume ... Application, & Geography - Global Forecast to 2020", published by ... Million by 2020, at a CAGR of 9.8% from 2015 ... 128 F igures spread th rough 187 P ...
Breaking Medicine Technology:
(Date:10/13/2015)... ... October 13, 2015 , ... ... Vereb has been named the organization’s Executive Vice President of Operations, and three ... to key leadership roles in the company. , Debbie Vereb’s appointment to Executive ...
(Date:10/13/2015)... (PRWEB) , ... October 13, 2015 , ... ... technologies and development solutions for drugs, biologics, consumer health and animal health products, ... Technology, and will lead a new, dedicated global team of drug development and ...
(Date:10/12/2015)... (PRWEB) , ... October 12, 2015 , ... According to an article published ... from adults today versus those of a similar group taken in 1988 has shown that ... a person in 2008 with the same diet as someone in 1971 would be on ...
(Date:10/12/2015)... ... October 12, 2015 , ... The American Society of Clinical ... professional education and clinical training in a health care discipline. , Many ... such as: losing weight, managing pain, or stopping smoking, etc. Frequently, extravagant statements ...
(Date:10/12/2015)... ... October 12, 2015 , ... AcousticSheep LLC, creators of the ... honor of Breast Cancer Awareness Month. During the month of October, for ... SleepPhones® Classic product to a breast cancer patient at the Cleveland Clinic. , ...
Breaking Medicine News(10 mins):