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Scientists Use Live Bacteria to Fight HIV
Date:7/18/2011

roup is hoping to start human trials of MucoCept within the next several years following completion of product development and safety testing.

These studies were funded by the National Institutes of Health, under federal grants from NIAID and DMID.  The MucoCept HIV project has also been supported by CONRAD-GMP, IPM, USAID, and the Bill and Melinda Gates Foundation.

REFERENCE: Mucosal Immunology; Advanced Online Publication July 6, 2011

http://www.nature.com/mi/journal/vaop/ncurrent/full/mi201130a.html

About Osel, Inc.

Osel Inc. is a biopharmaceutical company with a proprietary technology platform to develop next-generation probiotics as pharmaceutical products. In addition to MucoCept, Osel is developing an unmodified Lactobacillus crispatus product, LACTIN-V, as a natural antimicrobial-sparing intervention to prevent several common urogenital infections in women, including recurrent urinary tract infections (RUTI) and bacterial vaginosis. LACTIN-V was recently shown to reduce the rate of recurrent urinary tract infection in women by about one-half (Stapleton et al., Clin Infect Dis. 52:1212-1217, May 2011), which compares favorably to antimicrobial prophylaxis, the current standard of care for RUTI. MIYA-BM, containing the novel probiotic bacterium, Clostridium butyricum MIYAIRI 588, is an oral product in clinical development for the prevention of antimicrobial-associated diarrhea and Clostridium difficile infection. For further information, visit www.oselinc.com.

Media Contact
Dr. Laurel Lagenaur—Telephone: 650-964-1420—e-mail: llagenaur@oselinc.com


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