Navigation Links
Scientists Discover Why Teeth Form in a Single Row
Date:2/26/2009

Same Study Uncovers How Each Tooth Signals the Next to Start Growing

ROCHESTER, N.Y., Feb. 26 /PRNewswire-USNewswire/ -- A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published today in the journal Science. When completely understood, the genetic program described in the study may help guide efforts to re-grow missing teeth and prevent cleft palate, one of the most common birth defects.

Gene expression is the process by which information stored in genes is converted into proteins that make up the body's structures and carry its messages. As the baby's face takes shape in the womb, the development of teeth and palate are tightly controlled in space and time by gene expression. Related abnormalities result in the development of teeth outside of the normal row, missing teeth and cleft palate, and the new insights suggest ways to combat these malformations.

The current study adds an important detail to the understanding of the interplay between biochemicals that induce teeth formation, and others that restrict it, to result in the correct pattern. Specifically, researchers discovered that turning off a single gene in mice resulted in development of extra teeth, next to and inside of their first molars. While the study was in mice, past studies have shown that the involved biochemical players are active in humans as well.

"This finding was exciting because extra teeth developed from tissue that normally does not give rise to teeth," said Rulang Jiang, Ph.D., associate professor of Biomedical Genetics in the Center for Oral Biology at the University of Rochester Medical Center, and corresponding author on the Science paper. "It takes the concerted actions of hundreds of genes to build a tooth, so it was amazing to find that deleting one gene caused the activation of a complete tooth development
'/>"/>

SOURCE University of Rochester Medical Center
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Scientists Unmask Genetic Markers Associated With Psoriasis
2. 42 Top U.S. Scientists and Specialists Explore Cutting-Edge Innovations to Defend America From Dangerous Zoonotic Diseases
3. Gene Found Activated in 70% of Prostate Cancer Cases, George Washington University Medical Center Scientists Report
4. Battelle Scientists Named on Patent for Making Oxygen From Light and Water
5. Scientists Reveal Roadmap to Brain Health That Can Be Passed Down to Future Generations: Exercise, Omega-3, Folic Acid, Vitamin B6, and Vitamin B12
6. Tengion Scientists Publish Key Preclinical Findings Demonstrating the Benefits of Organ Regeneration Vs. Repair
7. Brain Stem Cells Can Be Awakened, Say Schepens Scientists
8. Infant Vaccines Produce Autism Symptoms in New Primate Study by University of Pittsburgh Scientists
9. ImQuest Scientists Present Important HIV Microbicide Development Results at Microbicides 2008 in Delhi, India
10. Neuroscientists Offer Hope for Breast Cancer Patients Suffering From Chemobrain
11. Researchers Discover Metabolite Linked to Aggressive Prostate Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 11, 2014 According to a ... Devices Market (Endoscopes, Endoscopic Operative Devices, and Visualization Systems) ... Forecast, 2013-2019" the global endoscopy devices market was valued ... to grow at a CAGR of 6.8% from 2013 ... 36.9 billion in 2019. Browse the full ...
(Date:7/11/2014)... 2014 Neurelis, Inc. ("Neurelis") today announced an ... option held by Biotie to purchase Neurelis, clearing the ... (intranasal diazepam) for pediatric and adult epilepsy patients who ... year, Biotie has advanced the development program for NRL-1 ... clinical work required for NDA submission to the FDA.  ...
(Date:7/10/2014)... 2014  Breg, Inc., a premier provider of ... FreeRunner™ knee brace with new innovations to help ... return to active lifestyles.  FreeRunner,s patent-pending design acts ... support when patients need it most, and the ... Patellofemoral issues are the most common cause ...
Breaking Medicine Technology:Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 2Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 3Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 4Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 5Global Endoscopy Devices Market is Expected to Reach USD 36.9 Billion by 2019: Transparency Market Research 6Neurelis Regains Rights to Intranasal Diazepam Program 2Neurelis Regains Rights to Intranasal Diazepam Program 3Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2
(Date:7/11/2014)... -- People with the lowest incomes may have a higher ... a new study suggests. People with PAD have narrowing ... often the legs. The condition causes leg pain and is ... body. People with PAD have a higher risk for heart ... people with PAD who took part in the U.S. National ...
(Date:7/11/2014)... The report, “Specialty Synthetic Fibers & Glass ... 2018,” defines and segments the specialty synthetic fibers ... forecast of the volumes and values of types ... aramids, UHMW Polyethylene, carbon fiber, partially oxidized polyacrylonitrile ... PBO fiber, and liquid crystal polymer fiber and ...
(Date:7/11/2014)... News) -- In people with sex addiction, pornography affects ... seen in drug addicts as they consume drugs, a ... brain activity between patients who have compulsive sexual behavior ... addicts," study author Dr. Valerie Voon, of the University ... release. Voon,s research involved 19 men with sex ...
(Date:7/11/2014)... Alliance for Cancer Gene Therapy, Inc. ... to cell and gene therapies for cancer – ... organization as Senior Development Officer. , Corday is ... gifts and addressing influential donors. Prior to joining ... NewYork Presbyterian Hospital/Columbia University Medical Center, where he ...
(Date:7/11/2014)... 2014 As reported by the ... 7/11/14), a significant number of severe adverse events such ... and even death from the highly-promoted and costly immune-system ... Times report , a regulatory filing revealed that ... patients was almost 14% of prescriptions, up from 9.1% ...
Breaking Medicine News(10 mins):Health News:Poor More Prone to Leg Circulation Trouble 2Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 2Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 3Health News:Specialty Synthetic Fibers & Glass Fiber Market Poised to Reach $20.1 Billion at a CAGR of 5.2% by 2018 – Report by MarketsandMarkets 4Health News:Brains of Sex Addicts May Be Wired Like Those of Drug Addicts, Study Finds 2Health News:Alliance for Cancer Gene Therapy (ACGT) Welcomes Joshua Corday as Senior Development Officer 2Health News:Alliance for Cancer Gene Therapy (ACGT) Welcomes Joshua Corday as Senior Development Officer 3Health News:Acthar’s Deadly Adverse Events Revealed 2Health News:Acthar’s Deadly Adverse Events Revealed 3
... many human beings. A new Mayo Clinic study reveals the ... definition of contact dermatitis is that it is a skin ... direct contact with an allergen. ,The ten allergens ... ,? Nickel (nickel sulfate hexahydrate ,? Gold (gold sodium ...
... data on men's health over the last two decades. The ... a semi annual survey.// Judging by the response, the Harvard ... on how men can maintain a satisfying sex life, as ... most prevalent illness in elderly men followed by chronic illnesses ...
... Mumbai were crippled as the striking doctors were determined to ... All the government hospitals in Mumbai suffered due to absence ... 15 government-managed hospitals in this bustling city of over 15 ... demanding better security while on the job after relatives of ...
... Cyriac Joseph has expressed the need for quality medical ... not leave any stone unturned to weed out black ... this is a matter of grave concern to the ... The educationists, professionals, governments and all the stakeholders in ...
... from Duke university Medical Center have established that ... influenced by a complex interplay between genetic and ... crucial role in determining the psychological and biological ... results of four such studies that examined the ...
... that the much dreaded bird flu virus may be carried across ... the potential of posing a serious health hazard, specifically in the ... bird flu viral strain. ,The exact mechanism of how ... if bird flu virus is found in birds in U.K, it ...
Cached Medicine News:Health News:Health Services Came To A Halt As Mumbai Doctors Strike Continues 2Health News:Genes And Environmental Factors Determine Stress Response 2
Curved shafts with 2.0 mm wide serrated tips and 0.4 mm pin in upper jaw. Serrated cross action handle with dull finish....
Angled insertion forcep used for the Hydroview lens. Manufactured in titanium....
Biconvex jaw design. 40 degree angled shafts. Tip to angle length: 7.5 mm. Locking handle. Manufacturing in titanium....
Titanium. Designed to easily fold the hydroview lens. Will also fold many styles of soft intraocular lenses. Unique cross-action design facilitates folding of the lens....
Medicine Products: