Navigation Links
Schering-Plough Reports Top-Line Results of the IDEAL Study
Date:1/14/2008

randomized to one of the three treatment regimens and received up to 48 weeks of combination therapy with 24 weeks of follow-up. SVR, the primary endpoint of the study, was similar for the three treatment regimens (40 vs. 38 vs. 41 percent, respectively).

Importantly, while end of treatment response was higher in the Pegasys combination therapy arm, IDEAL showed that fewer patients receiving PEGINTRON combination therapy relapsed after the end of treatment (24 vs. 20 vs. 32 percent, respectively).

Overall adverse events reported for the three treatment regimens were similar and, as seen in other studies with these treatments, a range of "flu- like symptoms" were the most commonly reported adverse events for all three treatment regimens. Discontinuation rates due to adverse events also were similar (13 vs. 10 vs. 13 percent, respectively).

"While the sustained response rates were similar in the IDEAL study, we were pleased to see that fewer patients relapsed following PEGINTRON combination therapy," said Robert J. Spiegel, M.D., chief medical officer and senior vice president, Schering-Plough Research Institute. "With these results, we now have, for the first time, a large body of well-controlled clinical data demonstrating how the similarities and differences of the two leading combination therapies for hepatitis C affect outcomes for patients. These findings provide important clinical-based evidence that will help physicians in making treatment decisions and in guiding their patients through what is a long and challenging course of therapy. We look forward to further analyses of this large data set to gain additional clinical insights into the management of this serious disease."

In IDEAL, the combination regimen of Pegasys and Copegus used the recommended doses in accordance with their approved U.S. labeling, which includes a flat dose of Pegasys (180 mcg/week) for all patients regardless of body weight, and 1,000 or 1,200 mg/day of Cop
'/>"/>

SOURCE Schering-Plough Corporation
Copyright©2008 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3 4 5 6 7 8 9

Related medicine technology :

1. Schering-Plough Announces Asenapine NDA Accepted for Filing by the U.S. FDA
2. Schering-Plough Highlights PEGINTRON(TM) Clinical Data Presentations at the American Association for the Study of Liver Diseases (AASLD) 2007 Annual Meeting
3. Pharmacopeia Earns Milestone Payment From Schering-Plough on Initiation of Phase 1 Clinical Trials of Novel Therapeutic Candidate
4. Schering-Plough Initiates Phase III Studies with Vicriviroc in Treatment- Experienced HIV Patients
5. Second Thoughts about Fluoride, Reports Scientific American
6. SuperGen Reports Initiation of Multi-arm Phase 1b Trial of Novel Tyrosine Kinase Inhibitor
7. Celator(R) Pharmaceuticals Reports CPX-351 Shows Anti-Cancer Activity in Leukemia Patients
8. Alfacell Reports Financial Results for First Quarter of Fiscal 2008
9. Epiphany Biosciences Reports Initiation of Phase 2 Study of Valomaciclovir for the Treatment of Acute Infectious Mononucleosis
10. Neptune Industries Reports Favorable Phase II Trial Results on Ento- Protein(TM)
11. Indevus Pharmaceuticals Reports Positive Results of Phase II Octreotide Implant Trial
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2013)... and DRESDEN, Germany , ... BioScience, a leading preclinical contract research provider and ... content-driven pharmacology, and Debiopharm Group™ (Debiopharm), a Swiss-based ... on the development of prescription drugs that target ... today announced that they have signed a research ...
(Date:5/22/2013)... 22, 2013  Aribex, Inc., manufacturer of the newly ... a new color option, black with gray trim, of ... veterinary markets. The popular white with light blue trim ... to be available and both models can be purchased ... (Photo: http://photos.prnewswire.com/prnh/20130522/CL19573 ) "Dental offices are ...
(Date:5/22/2013)... 22, 2013 Advanced Prenatal Therapeutics (APT), a ... will help alleviate the high blood pressure and other ... expected to be the first medical device specifically designed ... fetal death. Every year, preeclampsia affects approximately ... . It is characterized by high blood pressure ...
Breaking Medicine Technology:Cenix BioScience and Debiopharm Group Collaborate to Identify Predictive Biomarkers 2Cenix BioScience and Debiopharm Group Collaborate to Identify Predictive Biomarkers 3Cenix BioScience and Debiopharm Group Collaborate to Identify Predictive Biomarkers 4Aribex Unveils New Color of NOMAD Pro 2 2Advanced Prenatal Therapeutics - Using Targeted Apheresis to Treat Preeclampsia 2
... March 2, 2011 InspireMD ... system , has expanded its MGuard production facilities to ... behind the accelerating demand for MGuard include the recent ... protection to be considered for PCI of highly thrombotic ...
... 2011 Accumetrics, Inc., a privately-held developer and marketer ... point-of-care diagnostic system for measuring platelet reactivity to multiple ... an agreement with Portola Pharmaceuticals, Inc. to develop and ... clinical trials. The VerifyNow System is widely ...
Cached Medicine Technology:InspireMD Boosts MGuard Production Capacity 2Accumetrics Signs Development & Supply Agreement With Portola Pharmaceuticals, Inc. 2
(Date:5/23/2013)... (PRWEB) May 23, 2013 With crowded ... more popular. But according to Mike Whitfield, a bodyweight ... of equipment like the medicine ball can add a ... Whitfield runs BodyweightTorch.com, a website in which anyone can ... uses no equipment. Recently, he shared a video with ...
(Date:5/23/2013)... Studies show that kids and teens who ... less likely to be overweight, less likely to engage in ... have better relationships with their parents. , Despite ... family dinner expert and advocate Aviva Goldfarb . Over ... percent. When families do eat together, average mealtimes last a ...
(Date:5/23/2013)... May 23, 2013 Dr. Garber's ... condition specific remedies are now available at Whole Foods ... CA 92677. The line of natural biotherapy formulas continues ... Chain. , Represented by Brandstorm HBC (Los Angeles, CA), ... Markets throughout California, Nevada and Arizona, as well as ...
(Date:5/23/2013)... Brad Schmett, Broker Associate with Luxury Homes ... Palm Springs area real estate market will ... of the Annual Memorial Day Flower Drop at the ... , Culminating the festive three-day weekend, Valley residents will ... with flight exhibitions. However, the highlight of the Memorial ...
(Date:5/23/2013)... 23, 2013 To help members ... Walkingspree is pleased to announce integration of its ... devices. This new upgrade automatically transfers real-time step ... to track their company’s team standings, view progress ... fat burned. , Walkingspree also offers an integrated ...
Breaking Medicine News(10 mins):Health News:Unique Ab Exercise, the Medicine Ball Chop, Released from BodyweightTorch.com 2Health News:Family Dinner Expert and Cookbook Author Announces “Family Dinner Challenge” 2Health News:Dr. Garber's Natural Solutions Now Available at Whole Foods Market, Laguna Niguel, CA 2Health News:Annual Memorial Day Flower Drop Honors Veterans in Palm Springs California by Brad Schmett 2Health News:Walkingspree Expands Device Options with Fitbit to Increase Member Engagement in Corporate Wellness Programs 2Health News:Walkingspree Expands Device Options with Fitbit to Increase Member Engagement in Corporate Wellness Programs 3
... EAST LANSING, Mich. - With the help of a ... Michigan State University is creating a cross-discipline, mentored program ... in women,s health., MSU,s new Building Interdisciplinary Research Careers ... Department of Medicine in the College of Human Medicine, ...
... MD, MPH, an endocrinologist at Nationwide Children,s Hospital, has ... customized text messages to remind adolescent diabetes patients about ... study, Dr. Dyer found an increase in overall treatment ... Dyer began developing this pilot study after realizing the ...
... , THURSDAY, July 29 (HealthDay News) -- Although millions ... ward off osteoporosis, New Zealand researchers say the supplements have ... increase in the risk for heart attack among older people. ... suggest that people get their required calcium, if possible, from ...
... is a protein that is expressed in and on ... and antigen presenting cells. This protein is known for ... response. Additionally, Professor Shachar,s lab has previously shown that ... the immune system, and that its stimulation by its ...
... influencing both morbidity and recovery after surgery. The ... intervention, which may prevent later complications. A traditional ... to identify significant weight loss over time, significantly ... nutritional factor levels and functional measurements of muscle ...
... most common cancers worldwide, particularly in China. However, ... to treat. It is important to screen for ... possess anti-cancer properties. These dietary compounds may modify ... proliferation and apoptosis. Galangin could inhibit the methoxyresorufin ...
Cached Medicine News:Health News:MSU targets women's health research with $2.5 million grant 2Health News:Pilot study supports adolescent diabetes patients through personalized text messages 2Health News:Calcium Supplements Linked to Boost in Heart Attack Risk 2Health News:Calcium Supplements Linked to Boost in Heart Attack Risk 3Health News:Calcium Supplements Linked to Boost in Heart Attack Risk 4Health News:How to detect malnutrition in patients effectively? 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: