Navigation Links
Schering-Plough Reports Long-Term Vicriviroc Data From Phase II Open-Label Extension Study in Treatment-Experienced HIV-Infected Patients
Date:9/14/2009

SAN FRANCISCO, Sept. 14 /PRNewswire-FirstCall/ -- Schering-Plough Corporation (NYSE: SGP) today reported long-term data with vicriviroc, its investigational CCR5 receptor antagonist, from an ongoing, open-label extension of the Phase II VICTOR-E1 study in treatment-experienced HIV-infected patients. The results showed that vicriviroc plus optimized background therapy achieved durable virologic suppression and increased CD4 cell counts, and was generally well tolerated over two years of therapy. These 96-week results were presented at the 49th Annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC).(1)

The study involved 85 treatment-experienced HIV-infected patients who received 48 weeks of open-label vicriviroc (30 mg once daily) plus an optimized antiretroviral regimen containing a ritonavir-boosted protease inhibitor after completion of 48 weeks of treatment in the double-blind phase of the VICTOR-E1 study (total of 96 weeks). More than half of these patients began open-label treatment with undetectable virus, i.e. an HIV-1 RNA level of less than 50 copies/mL, and about two-thirds had less than 400 copies/mL. Seventy patients remained on therapy at the time of the 96-week analysis. The virologic effect seen during the double-blind phase of the study was sustained in these patients during open-label vicriviroc treatment, with the percentage of patients achieving undetectable virus increasing over the course of therapy. Importantly, further improvements in CD4 counts were observed with longer vicriviroc therapy, with a mean increase of 50 cells/mm3 from week 48 of the double-blind study to the end of the 96-week period.

The data also showed that vicriviroc was generally well tolerated in this highly treatment-experienced population.
'/>"/>

SOURCE Schering-Plough Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Schering-Plough Announces U.S. Filing of Mometasone Furoate/Formoterol Fumarate Combination for the Maintenance Treatment of Asthma
2. Schering-Plough Expands Vicriviroc Phase II Study in Treatment-Naive Patients With HIV
3. Schering-Plough Highlights Hepatitis C Clinical Data Presentations at the European Association for the Study of the Liver (EASL) Annual Meeting
4. Schering-Plough Announces Results of the Early ACS Trial
5. Schering-Ploughs Investigational Oral Thrombin Receptor Antagonist Meets Primary Endpoint in a Newly Published Study
6. Schering-Plough Highlights R&D Pipeline Progress, Innovation and Breadth of Research Projects
7. Schering-Plough Provides Update on Boceprevir Clinical Development and Introduces Potent Next-Generation Oral HCV Protease Inhibitor for Treating Patients With Chronic Hepatitis C
8. Schering-Plough Unveils Top-Line Study Results for SAPHRIS(TM) (asenapine) Demonstrating Efficacy in Long-Term Schizophrenia Relapse Prevention
9. Schering-Plough Reports Preladenant Meets Primary Endpoint in Phase II Dose-Finding Trial for Parkinsons Disease
10. Schering-Plough Announces European Launch of BRIDION(R) (Sugammadex)
11. Schering-Plough Announces Phase III Data for Sustained Follicle Stimulant
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Sept. 30, 2014  Hologic, Inc. (NASDAQ: ... Hologic,s President and Chief Executive Officer, will preside over ... 1, the first day of Breast Cancer Awareness Month. ... campaign focused on the important benefits of Hologic,s 3D ... FDA as clinically superior to traditional mammography. ...
(Date:9/30/2014)... 2014  Tasly Pharmaceuticals, Inc., the world,s leader ... today the launch of Deepure. Deepure ... men and women concerned with supporting their overall ... age while helping keep their health care cost ... herb-based formulas, namely, ProHeart PLUS, ImmunoPower PLUS, and ...
(Date:9/30/2014)... 30, 2014 STUDY OBJECTIVES The ... to provide an overview of the current and ... drugs/therapeutics. The key objective is to present a ... as an important tool in the treatment of ... future strategies within the protein therapeutics market, which ...
Breaking Medicine Technology:Hologic to Kick Off National Breast Cancer Awareness Month at the October 1 NASDAQ Stock Market Opening Bell Ceremony 2Hologic to Kick Off National Breast Cancer Awareness Month at the October 1 NASDAQ Stock Market Opening Bell Ceremony 3Global Markets and Manufacturing Technologies for Protein Drugs -- Focus on Cytokines and Monoclonal Antibodies 2Global Markets and Manufacturing Technologies for Protein Drugs -- Focus on Cytokines and Monoclonal Antibodies 3Global Markets and Manufacturing Technologies for Protein Drugs -- Focus on Cytokines and Monoclonal Antibodies 4
... 13 Dynatronics Corporation (Nasdaq: DYNT ) today announced ... , Net income for the fiscal first quarter was $68,625 ... ($.01 per share) for the comparable prior year period. Sales ... $7,996,149 for the first quarter of the prior fiscal year. ...
... Eli Lilly and Company (NYSE: LLY ) announced ... science and technology, and president, Lilly Research Laboratories, will ... also announced that Jan M. Lundberg, Ph.D., executive vice ... to become his successor. Paul is committed to working ...
Cached Medicine Technology:Dynatronics Announces Positive Financial Results for Quarter 2Dynatronics Announces Positive Financial Results for Quarter 3Dynatronics Announces Positive Financial Results for Quarter 4Dr. Steven M. Paul to Retire from Lilly as Executive Vice President, Science and Technology, President, Lilly Research Laboratories; Dr. Jan M. Lundberg, Executive Vice President, Head of Global Discovery Research, AstraZeneca, Named his Successor 2Dr. Steven M. Paul to Retire from Lilly as Executive Vice President, Science and Technology, President, Lilly Research Laboratories; Dr. Jan M. Lundberg, Executive Vice President, Head of Global Discovery Research, AstraZeneca, Named his Successor 3
(Date:10/1/2014)... (PRWEB) October 01, 2014 Phoseon Technology, ... , continues to expand the business worldwide. This rapid ... with additional capacity for manufacturing efforts. The company has ... last five years and expects this growth to continue ... curing technology gains worldwide adoption. , “We are ...
(Date:10/1/2014)... 01, 2014 Beverly Hills licensed Clinical ... is celebrating 20 years of private practice in her ... people to achieve greater joy and fulfillment in their ... warning signs and suggestions for anyone who suspects they ... “Believe it or not, it’s not always easy ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Anti Aging ... and skin rejuvenating destination of choice, is announcing a ... October through to December. , “We’re doing this because ... possible to our top skin clinic in Toronto,” says ... do so much at Anti Aging Clinic, including laser ...
(Date:10/1/2014)... October is national Breast Cancer Awareness Month—an annual ... raising money for breast cancer research. Pelican Water is ... in the effort to find a cure. , ... having access to clean, healthy water. Research has shown ... forms of cancer. , The Problem of Chlorine ...
(Date:10/1/2014)... Washington, DC (PRWEB) October 01, 2014 ... of all retail generics increasing in price in the ... Information Services, Inc.’s (AIS) Drug Benefit News (DBN) interviewed ... this trend means for pharmacies and health plans. ... pace with rising generic acquisition costs, these cost increases ...
Breaking Medicine News(10 mins):Health News:Phoseon Technology Continues to Drive Growth Worldwide 2Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 2Health News:Prominent Beverly Hills Psychologist Dr. Kathleen Mojas Celebrating 20 Years in Private Practice Identifies Common Warning Signs That You May Be In a Toxic Relationship. 3Health News:Anti Aging Clinic, the GTA’s Premier Provider of Anti Aging Treatments, Announces Deal on Units of Botox 2Health News:Pelican Water Supports Breast Cancer Awareness Month with Order Donations 2Health News:Rising Generic Drug Prices Affect Pharmacies, Insurers Alike, Reports AIS Newsletter 2Health News:Rising Generic Drug Prices Affect Pharmacies, Insurers Alike, Reports AIS Newsletter 3
... the U.S. and Canada have been selected to participate ... initiative in immunotherapy funded by the National Cancer Institute ... will establish a network of top academic immunologists to ... patients, own immune systems to fight their cancer. , ...
... , WEDNESDAY, April 6 (HealthDay News) -- Poor ... have the condition diagnosed, but this disparity has decreased in ... data on children in California and found that the average ... born in 1992 to 3.8 years for those born in ...
... the April 5 White House Press Briefing, President Barack Obama ... in Congress from both political parties in order to avoid ... he has matched the initial House of Representatives, proposal to ... only in areas of priority. He expressed that neither side ...
... neonatal horse can be a challenging patient. Its immune system is ... like most infants it wants to stay close to mom. ... Pamela Wilkins , a professor of equine internal medicine and ... a new paper on equine neonatal intensive care. The ...
... to find such high levels of PCBs, highly toxic compounds ... a region such as the western coast of Africa", Ailette ... (UPV/EHU-Spain) and co-author of a study published in the journal ... which some studies have shown to be carcinogenic compounds, were ...
... over, newts and salamanders. The mouse may join you as ... Researchers are reporting that a simple chemical cocktail can coax ... in the first stages of a regenerating limb. Their study, ... the biological raw material for a new limb, appears in ...
Cached Medicine News:Health News:Fred Hutchinson Cancer Research Center to lead Immunotherapy Clinical Trials Network 2Health News:Fred Hutchinson Cancer Research Center to lead Immunotherapy Clinical Trials Network 3Health News:Fred Hutchinson Cancer Research Center to lead Immunotherapy Clinical Trials Network 4Health News:Autism Diagnoses Still More Likely in Richer Neighborhoods 2Health News:AADR applauds President Obama's support for maintaining biomedical research in FY11 2Health News:Treating newborn horses: A unique form of pediatrics 2Health News:Treating newborn horses: A unique form of pediatrics 3Health News:High levels of toxic compounds found on coasts of West Africa 2
... AFP IRMA,is an immunoradiometric assay ... (AFP) in serum. It is,intended ... in either of,two contexts:, (a) ... the,management of patients with,nonseminomatous testicular ...
Coat-A-Count PAP IRMA,is an immunoradiometric assay designed,for the quantitative measurement of,prostatic acid phosphatase (PAP) in,serum. It is intended strictly for in vitro,diagnostic u...
The MOSAIC PET scanner is designed to meet the exacting requirements of animal research imaging. Supported by proven Philips technology, MOSAIC provides a leading edge PET solution for reliable in-vi...
... EEG recording is assured even in the ... has high performance, high sensitivity amplifiers, high ... filter, shielded electrodes and a high performance ... is a complete and ready to ...
Medicine Products: