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Schering-Plough Initiates Phase III Studies with Vicriviroc in Treatment- Experienced HIV Patients
Date:9/17/2007

ase inhibitor boosted by ritonavir and at least two drugs that are active, based on susceptibility testing. The optimized background therapy will be chosen by the investigator based on results of drug susceptibility tests performed at screening, patient history of prior antiretroviral drug use and drug toxicity.

The VICTOR-E3 and VICTOR-E4 studies will also evaluate the safety and tolerability of vicriviroc compared to placebo, each given in combination with an optimized background therapy. An independent, external Data Safety Monitoring Board (DSMB) will review study data on a regular basis to assure continued safety of the participants.

For more information about the VICTOR-E3 and VICTOR-E4 clinical studies, please visit http://www.clinicaltrials.gov, search term: vicriviroc.

About Schering-Plough

Schering-Plough is a global science-based health care company with leading prescription, consumer and animal health products. Through internal research and collaborations with partners, Schering-Plough discovers, develops, manufactures and markets advanced drug therapies to meet important medical needs. Schering-Plough's vision is to earn the trust of the physicians, patients and customers served by its approximately 33,500 people around the world. The company is based in Kenilworth, N.J., and its Web site is http://www.schering-plough.com.

SCHERING-PLOUGH DISCLOSURE NOTICE: The information in this press release includes certain "forward-looking statements" within the meaning of the Private Securities Litigation Reform Act of 1995, including statements relating to the timing of clinical trials, the company's plans and the potential for vicriviroc. Forward-looking statements relate to expectations or forecasts of future events. Schering-Plough does not assume the obligation to update any forward-looking statement. Many factors
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