Navigation Links
Schering-Plough Announces Results of the Early ACS Trial
Date:3/30/2009

Early Use of INTEGRILIN(R) Investigational Dosing is Not Superior to Delayed Provisional Use in Patients with High-Risk Acute Coronary Syndrome, Study Finds

KENILWORTH, N.J., March 30 /PRNewswire-FirstCall/ -- In a study presented today at the 58th annual Scientific Sessions of the American College of Cardiology and simultaneously published by The New England Journal of Medicine, researchers reported that a strategy using an upstream, investigational dose of INTEGRILIN(R) (eptifibatide) routinely in patients with Acute Coronary Syndrome (ACS), at least 12 hours prior to angiography, failed to achieve either the primary or secondary endpoints of the trial. Significantly higher rates of bleeding and transfusions also were reported.

"These results do not support the upstream use of double-bolus plus infusion eptifibatide as a routine course of treatment in ACS," said Enrico Veltri, M.D., group vice president of global clinical research, cardiovascular and metabolic disease, Schering-Plough Research Institute. "However, the results do not change what other studies have previously reported: that eptifibatide remains an integral component of therapy for appropriate patients undergoing PCI."

L. Kristin Newby, MD, associate professor of medicine at Duke Clinical Research Institute, presented the results of the nearly 9,500-patient Early Glycoprotein IIb-IIIa Inhibition in Non-ST-Segment Elevation Acute Coronary Syndrome (EARLY ACS) study, which was designed to determine whether routine early use of eptifibatide would result in improved cardiovascular outcomes for patients with ACS compared to delayed provisional use. The primary efficacy endpoint was a composite of death, (re)infarction (MI), recurrent ischemia requiring urgent revascularization, or thrombotic bailout through 96 hours. The secondary endpoint was death or (re)MI at 30 days. Safety endpoints included bleeding and transfusions through 120 hours.

<
'/>"/>
SOURCE Schering-Plough
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Schering-Ploughs Investigational Oral Thrombin Receptor Antagonist Meets Primary Endpoint in a Newly Published Study
2. Schering-Plough Highlights R&D Pipeline Progress, Innovation and Breadth of Research Projects
3. Schering-Plough Provides Update on Boceprevir Clinical Development and Introduces Potent Next-Generation Oral HCV Protease Inhibitor for Treating Patients With Chronic Hepatitis C
4. Schering-Plough Unveils Top-Line Study Results for SAPHRIS(TM) (asenapine) Demonstrating Efficacy in Long-Term Schizophrenia Relapse Prevention
5. Schering-Plough Reports Preladenant Meets Primary Endpoint in Phase II Dose-Finding Trial for Parkinsons Disease
6. Schering-Plough Announces European Launch of BRIDION(R) (Sugammadex)
7. Schering-Plough Announces Phase III Data for Sustained Follicle Stimulant
8. About 60 Clinical Studies Regarding Schering-Ploughs Oncology Compounds Will be Presented at ASCO
9. Schering-Plough To Initiate Phase III Studies With HCV Protease Inhibitor Boceprevir in Previously Untreated Hepatitis C Patients and Those Who Failed Prior Treatment
10. Schering-Plough Highlights PEGINTRON(TM) and Boceprevir Hepatitis C Data Presentations at Digestive Disease Week (DDW) Annual Meeting
11. Schering-Plough Highlights PEGINTRON(TM) and Boceprevir Data Presentations at European Association for the Study of the Liver (EASL) Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... CORAL SPRINGS, Florida , April 21, 2015 /PRNewswire/ ... in the U.S. are expected to grow at a ... for companies & vendors that provide technology services for ... Companies in focus today are: Surna Inc. (OTC: SRNA), ... (OTC: MJNA), Breathe, E-Cigs Corp. (OTC: BVAP), 22 nd ...
(Date:4/21/2015)... , April 21, 2015  Decision Diagnostics ... administrator and the exclusive worldwide sales, service and ... the FDA-cleared Green Alternative Strip, specifically designed to ... LifeScan OneTouch Ultra family of glucose testing meters, ... announced today that Johnson & Johnson/Lifescan has requested ...
(Date:4/21/2015)... , April 21, 2015  Navitas has launched ... a wide range of offerings for life sciences clients. ... an integrated platform enabling seamless flow of data across ... the Aviator launch, Navitas worked closely with Oracle to ... and Oracle,s CTMS in the Cloud. ...
Breaking Medicine Technology:New Technology, Innovative Products & State-of-the-Art Equipment in the Legal Cannabidiol Industries Continue to Provide Growing Revenue Opportunities 2New Technology, Innovative Products & State-of-the-Art Equipment in the Legal Cannabidiol Industries Continue to Provide Growing Revenue Opportunities 3New Technology, Innovative Products & State-of-the-Art Equipment in the Legal Cannabidiol Industries Continue to Provide Growing Revenue Opportunities 4New Technology, Innovative Products & State-of-the-Art Equipment in the Legal Cannabidiol Industries Continue to Provide Growing Revenue Opportunities 5New Technology, Innovative Products & State-of-the-Art Equipment in the Legal Cannabidiol Industries Continue to Provide Growing Revenue Opportunities 6New Technology, Innovative Products & State-of-the-Art Equipment in the Legal Cannabidiol Industries Continue to Provide Growing Revenue Opportunities 7Decision Diagnostics Shrugs Off New Attack As Johnson & Johnson Panics In Patent Case 2Decision Diagnostics Shrugs Off New Attack As Johnson & Johnson Panics In Patent Case 3Navitas Launches Aviator - Cloud Based Platforms for Oracle Solutions 2Navitas Launches Aviator - Cloud Based Platforms for Oracle Solutions 3Navitas Launches Aviator - Cloud Based Platforms for Oracle Solutions 4
... Md., Dec. 15, 2011  GP Strategies Corporation (NYSE: ... merger of GP Strategies Corporation with and ... current holding company structure. General Physics, which is the ... surviving legal corporation and will be renamed GP Strategies ...
... the industry leader in innovative shape memory orthopedic devices, today ... United States Copyright and Patent Office for its innovative shape ... was granted December 6, 2011 for a "Method and Apparatus ... memory polymers are advanced materials that can "remember" more than ...
Cached Medicine Technology:GP Strategies Shareholders Approve Elimination of Holding Company Structure and Renaming of General Physics Corporation 2GP Strategies Shareholders Approve Elimination of Holding Company Structure and Renaming of General Physics Corporation 3MedShape, Inc. Awarded U.S. Patent for Deploying Shape Memory Polymer Devices in Medical Applications 2
(Date:4/21/2015)... Los Angeles, CA (PRWEB) April 21, 2015 ... Instead, it opened its doors today in the leafy, ... with a refreshed look and a new theme of “Disconnect ... the new owner of the award-winning day spa, announces ... in time for special Mother’s Day offerings that help celebrate ...
(Date:4/21/2015)... Utah (PRWEB) April 21, 2015 Zane ... businesses, announced today its CEO Rick Lindquist has been ... for 2015. , According to Rick Lindquist, “There is ... industry, and Zane Benefits’ small business solutions are at ... recognition provided by Employee Benefit Adviser’s Rising Stars.” , ...
(Date:4/21/2015)... has released a new blog post explaining the importance of ... on a uto insurance prices . , Drivers ... for advantageous auto insurance discounts. Clients can now review multiple ... will also help them get the best rates in their ... cost coverage is no longer difficult as there are multiple ...
(Date:4/21/2015)... Optimity Advisors ( Optimity), ... that helps clients in complex industries navigate rapid ... Association of Community Affiliated Plans (ACAP) ... 58 local, not-for-profit, community-affiliated Safety Net Health Plans ... primarily enrolled in public or state-sponsored coverage programs, ...
(Date:4/21/2015)... Quark Software Inc. has introduced ... solution that enables large enterprises to streamline the ... With Quark Procedure Management, corporate writers and subject ... to save, search and update, which is critical ... issues. Examples of policies and procedures include employee ...
Breaking Medicine News(10 mins):Health News:Larchmont Sanctuary Spa Revealed as New Name For Neighborhood Spa; New Owner, New Eco Offerings & New Theme: “Disconnect to Reconnect” 2Health News:Larchmont Sanctuary Spa Revealed as New Name For Neighborhood Spa; New Owner, New Eco Offerings & New Theme: “Disconnect to Reconnect” 3Health News:Zane Benefits’ CEO Named Top 20 Rising Stars 2Health News:Auto Insurance Quotes Offer Excellent Security for A Car 2Health News:Optimity Advisors Named Preferred Vendor by the Association of Community Affiliated Plans (ACAP) 2Health News:Quark Software Inc. Introduces Procedure Management Solution for Global 2000 2Health News:Quark Software Inc. Introduces Procedure Management Solution for Global 2000 3
... By Jenifer Goodwin HealthDay Reporter , THURSDAY, ... falling behind on your mortgage payments hurts more than just ... with the struggle can also harm your physical and psychological ... on nearly 2,500 Americans who took part in the Health ...
... News) -- Most Americans consume too much sodium, and new ... of dietary salt, according to a new study by federal ... with increased risk of high blood pressure, which can lead ... people aged 2 years and older should limit daily sodium ...
... University of Houston (UH) are recommending a new strategy for ... diseases. In an invited review published in the ... at the Center for Nuclear Receptors and Cell Signaling (CNRCS) ... the team,s 1996 discovery of the estrogen receptor beta (ERβ). ...
... 20 (HealthDay News) -- There,s a suicide every 15 minutes in ... her own life there are many more who think about, plan ... The analysis of 2008-09 data from the National Survey on Drug ... range from about 1 in 50 adults in Georgia (2.1 percent) ...
... HOUSTON -- (Oct. 20, 2011) -- Bioengineers from Rice University ... a new "law of biology" can predict when a critically ... treatment is likely to prevent it. "We want to ... the principal investigator on a new $1.5 million grant from ...
... announce findings published in the October 20 issue of ... the inhibition of both microRNA-33a and microRNA-33b (miR-33a/b) with ... cause a sustained increase in high density lipoprotein cholesterol ... in the last decade has opened new insights for ...
Cached Medicine News:Health News:Foreclosure Crisis Threatening Americans' Health: Study 2Health News:Foreclosure Crisis Threatening Americans' Health: Study 3Health News:U.S. Diet Still Has Too Much Salt, CDC Warns 2Health News:New drug strategies for Alzheimer's, multiple sclerosis examined at UH 2Health News:Suicide Rates Vary by Region: CDC 2Health News:Cloudy with a chance of sudden death 2Health News:Cloudy with a chance of sudden death 3Health News:Novel therapeutic target identified to decrease triglycerides and increase 'good' cholesterol 2
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medtronic Ophthalmics offers a comprehensive selection of corneal trephine,blades and handles. Handcrafted, sharp, uniform blade edges promote a,symetrical and vertical cut of all corneal layers....
Medicine Products: