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Sanofi-aventis and Sunnybrook Health Sciences Centre Agree to Develop Treatment for Diabetic Foot Ulcers
Date:2/15/2011

n patients with diabetes mellitus. Neuropathic diabetic foot ulcers are a type of diabetic foot ulcer associated with diabetic peripheral sensorimotor neuropathy. The lack of sensation in the foot in combination with other factors, such as foot deformities and unperceived trauma (e.g., inappropriate footwear) leads to skin breakdown. Neuroischemic diabetic foot ulcers are ulcers occurring in patients with diabetic neuropathy and decreased blood flow to the foot due to peripheral arterial disease, commonly seen in diabetic patients. Neuroischemic ulcers are associated with significant morbidity and mortality as well as high costs of medical care (related to hospital costs, revascularization and wound-related procedures, and management of infection).  If untreated over time or infected beyond repair, neuroischemic foot ulcers may damage one's foot to such an extent that amputation is unavoidable.  

About sanofi-aventisSanofi-aventis, a leading global pharmaceutical company, discovers, develops and distributes therapeutic solutions to improve the lives of everyone. Sanofi-aventis is listed in Paris (EURONEXT: SAN) and in New York (NYSE: SNY).  For more information, please visit www.sanofi-aventis.com

About Sunnybrook Health Sciences Centre Sunnybrook Health Sciences Centre is inventing the future of health care for the one million patients the hospital cares for each year through the dedication of its more than 10,000 staff and volunteers. An internationally recognized leader in research and education and a full affiliation with the University of Toronto distinguishes Sunnybrook as one of Canada's premier academic health sciences centres. Sunnybrook specializes in caring for Canada's war veterans, high-risk pregnancies, critically ill newborns, adults and the elderly, and treating and preventing cancer, cardiovascular disease, neurological and psychiatric disorders, orthopedic disorders and
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