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Sanofi-aventis Oncology Data to be Presented at San Antonio Breast Cancer Symposium
Date:12/9/2010

BRIDGEWATER, N.J., Dec. 9, 2010 /PRNewswire-FirstCall/ -- Sanofi-aventis (EURONEXT: SAN and NYSE: SNY) announced today that the final survival analysis (10-year follow-up) of the BCIRG001 study that included a Taxotere® (docetaxel) Injection Concentrate chemotherapy treatment regimen in the adjuvant breast cancer setting, as well as data from iniparib (BSI-201) pre-clinical and clinical breast cancer studies will be featured during the 33rd Annual San Antonio Breast Cancer Symposium (SABCS) in San Antonio, Texas from December 8 to 12, 2010.  

During SABCS, the final (10-year follow up) survival analysis of the BCIRG001 study that included sanofi-aventis' chemotherapy drug Taxotere, in combination with doxorubicin and cyclophosphamide, in women with operable node-positive breast cancer will be presented. Also being presented are data from pre-clinical and clinical studies involving the sanofi-aventis investigational compound iniparib (BSI-201), which is being studied in breast cancer.  Iniparib is a novel investigational small molecule with poly (ADP-ribose) polymerase (PARP) inhibitory activity.

Key events at SABCS include: Taxotere Data:Abstract #S4-3

Friday, Dec. 10

3:45 PM CSTAn oral presentation featuring final results from the ten-year follow-up analysis of the BCIRG 001 trial Iniparib Data:Abstract #P5-06-09

Phase 1b/2 MBC trial

Saturday, Dec. 11

5:30 - 7:30 PM CSTData from a Phase 1b study to assess the safety and tolerability of the investigational compound iniparib (BSI-201) in combination with irinotecan in patients with metastatic breast cancer (MBC)Iniparib Data:Abstract # P6-04-12

Activity in TNBC Cell lines

Sunday, Dec. 12

7:00 - 8:30 AM CSTData from a preclinical study assessing the cell cycle effects of the investigational compound iniparib (BSI-201) in combination
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